Neurology

Background: Children with developmental disorders experience chronic gastrointestinal symptoms. Aims: To examine the nature of these gastrointestinal symptoms and histologic findings in children with autism spectrum/developmental disorders and ileocolonic disease. Methods: Chart review. 143 autism spectrum/developmental disorder patients, with chronic gastrointestinal symptoms, undergoing diagnostic ileocolonoscopy. Results: Diarrhea was present...

Differences in the frequency of several somatic conditions have been tentatively reported between the diagnostic sub-groups of pervasive developmental disorder (PDD). Retrospective cross-sectional analysis of a database was used to test these preliminary findings. A sample of 1189 children diagnosed with autism (n = 267), Asperger syndrome (n = 210)...

No abstract.

Stress-related diseases have been predicted to become major contributors to the Global Disease Burden within the next 20 years. Of these, depression is one of the principal identifiable sources of concern for public mental health, and has been hypothesized to be an outcome of prolonged stress. Examination of the hyper-responsiveness...

Background and Methods: Anthroposophic treatment for anxiety disorders includes special artistic and physical therapies and special medications. We conducted a prospective cohort study of 64 consecutive adult outpatients starting anthroposophic treatment for anxiety disorders under routine conditions. Main outcomes were Anxiety Severity (physician and patient ratings 0–10), Self-rating Anxiety Scale...

Background: Bipolar disorder is a lifelong problem with imperfect available treatments. Recent research has shown potential benefit of nutritional treatment for mood symptoms. The goal of the current study was to determine whether adults with bipolar disorder reported treatment benefit from consuming a micronutrient formula. Methods: Self-report data were...

Introductory Editorial from Dr Jaswinder Kaur Ghuman, Associate Professor of Psychiatry and Pediatrics, College of Medicine, University of Arizona, Tucson, Arizona 85724 U.S.A.

Robert G Bota1, Timothy Dellenbaugh2, Andro Giorgadze3, Chadd K Eaglin4 and Cristina Davila1 1Assistant Clinical Professor of Psychiatry, University of Missouri-Kansas City. 2Associate Professor of Psychiatry, University of Missouri-Kansas City. 3Psychiatrist, Middle Flint Behavioral Health Care, Americus, GA. 4Resident Psychiatrist, University of Hawaii. Abstract Objective: To assess...

Introductory Editorial by Dr David A. Fishbain, Professor of Psychiatry and Adjunct Professor Neurological Surgery and Anesthesiology, Miller School of Medicine at the University of Miami.

R.S. Grant1,2, S.E. Coggan1 and G.A. Smythe21School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney NSW, 2052. 2Australasian Research Institute, Sydney Adventist Hospital, 185 Fox Valley Rd., Wahroonga, NSW, 2076. AbstractPicolinic Acid is an endogenous metabolite of L-tryptophan (TRP) that has been reported to possess a...

Nady Braidy1, Ross Grant1,2, Bruce J Brew3,4, Seray Adams1, Tharusha Jayasena5 and Gilles J. Guillemin1,41University of New South Wales, Faculty of Medicine, Sydney, Australia. 2Australasian Research Institute, Sydney Adventist Hospital, Sydney, Australia. 3St. Vincent’s Centre for Applied Medical Research, Sydney, Australia. 4Department of Neurology, St. Vincent’s Hospital, Sydney, Australia. 5Bioanalytical...

Kazuhiro Nakamura1 and Hiroyuki Hasegawa21Department of Pathology, Juntendo University School of Medicine, Tokyo 113-8421, Japan. 2Department of Biosciences, Teikyo University of Science and Technology, Uenohara, Yamanashi 409-0193, Japan.AbstractSerotonin (5-hydroxytryptamine [5-HT]) has been implicated in a variety of physiological and pathological functions. Multiple steps of enzyme reactions enable biosynthesis of 5-HT....

Dawn M Richard1, Michael A Dawes1, Charles W Mathias1, Ashley Acheson2, Nathalie Hill-Kapturczak1 and Donald M Dougherty11Neurobehavioral Research Laboratory and Clinic, Department of Psychiatry. 2Research Imaging Center, University of Texas Health Science Center at San Antonio, U.S.A.AbstractAn essential component of the human diet, L-tryptophan is critical in a number of...

Robert SchwarczDepartment of Psychiatry, Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Tetsuya Goto1, Takahiro Miyahara1, Kazutaka Toyoda3, Jun Okamoto2, Yukinari Kakizawa1, Jun-ichi Koyama1, Masakatsu G. Fujie2 and Kazuhiro Hongo11Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan. 2Faculty of Science and Engineering, Waseda University, Tokyo, Japan. 3Graduate School of Science and Engineering, Waseda University, Tokyo, Japan. AbstractObject: Robotic surgery can...

Takahira Yamauchi, Manabu Makinodan, Tomohisa Nagashima, Kuniaki Kiuchi, Yoshinobu Noriyama and Toshifumi KishimotoDepartment of Psychiatry, Nara Medical University Faculty of Medicine, Kashihara, Japan.AbstractA 55-year-old man with schizophrenia developed water intoxication due to primary polydipsia. His manner of antidiuretic hormone secretion was investigated by water loading and infusion of hypertonic saline...

W. Oliver Tobin1,4, Joseph G. Hentz2, Bentley J. Bobrow3 and Bart M. Demaerschalk41Department of Neurology, Adelaide and Meath Hospital, Dublin, incorporating the National Children’s Hospital, Trinity College Dublin, Republic of Ireland. 2Department of Biostatistics, Mayo Clinic Arizona, U.S.A. 3Department of Emergency Medicine, Mayo Clinic Arizona, U.S.A. 4Department of Neurology, Mayo...

Bentley J. Bobrow1, Bart M. Demaerschalk2, Joseph P. Wood1, Albert Villarin3, Lani Clark4 and Anthony Jennings51Department of Emergency Medicine Mayo Clinic, Scottsdale, Arizona. 2Department of Neurology ,Mayo Clinic, Scottsdale, Arizona. 3Albert Einstein Medical Center, Philadelphia, Pennsylvania. 4Arizona Department of Health Services, Bureau of Emergency Medical Services, Phoenix, Arizona. 5St. Joseph’s...

PK (Poh-Kooi) LohDepartment of Geriatric Medicine, Royal Perth Hospital, Wellington Street, Perth, Western Australia 6000.AbstractThe use of Telemedicine in the assessment of cognitive impairment and Alzheimer’s Disease is evolving with advances in Information and Communication Technology. This article outlines the course of evolution in Western Australia, a large state with...

In this study we used incorporation of the DNA synthesis marker 5-bromo-2’-deoxyuridine or BrdU to visualize cell proliferation in the visual system of the adult mouse as a response to monocular enucleation. We detected new BrdU-labeled cells in different subcortical retinal target regions and we established a specific time frame...

Recent studies on the anatomical and functional organization of GABAergic networks in central auditory circuits of the zebra finch have highlighted the strong impact of inhibitory mechanisms on both the central encoding and processing of acoustic information in a vocal learning species. Most of this work has focused on the...

Katherine G. Akers1 and Paul W. Frankland1-31Neurosciences and Mental Health, Hospital for Sick Children, Toronto, Canada. 2Department of Physiology, University of Toronto, Toronto, Canada. 3Institue of Medical Science, University of Toronto, Toronto, Canada.AbstractIn humans, hippocampal damage typically produces temporally graded retrograde amnesia, with relative sparing of remote memories compared to...