Research methodologies
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- Interview with Clinical Medicine Insights: Oncology editorial board member Prof. M. Wasif Saif
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- 18/Jun/2010
- Interview with Biomarkers in Cancer editorial board member Dr Xiaofeng Zhou
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- 18/Jun/2010
- Interview with Microbiology Insights editorial board member Dr Viroj Wiwanitkit
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- 18/Jun/2010
- Interview with Cell & Tissue Transplantation & Therapy editorial board member Dr Terje Forslund
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- 17/Jun/2010
- Interview with Nutrition and Metabolic Insights editorial board member Prof.Abdulaziz I.AL-Othaimeen
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- 17/Jun/2010
- Interview with Biomarker Insights editorial board member Dr Steven R. Myers
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- 16/Jun/2010
- Interview with Immunology and Immunogenetics Insights editorial board member Dr Robert Yarchoan
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- 16/Jun/2010
- Interview with International Journal of Tryptophan Research editorial board member Dr Martin Reuter
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- 15/Jun/2010
- Interview with Cancer Informatics editorial board member Dr Philip Crooke
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- 15/Jun/2010
- Interview with Environmental Health Insights editorial board member Dr Lalita Bharadwaj
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- 15/Jun/2010
- Interview with Integrative Medicine Insights editorial board member Dr Merrijoy Kelner
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- 15/Jun/2010
- Interview with Clinical Medicine Insights: Reproductive Health editorial board member Dr Lior Lowenstein
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- 15/Jun/2010
- Interview with Clinical Medicine Insights: Trauma and Intensive Medicine editorial board member Dr Michael Y. Wang
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- 09/Jun/2010
- Interview with Environmental Health Insights editorial board member Dr Lars Carlsen
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- 09/Jun/2010
- Interview with Evolutionary Bioinformatics editorial board member Dr Carsten Wiuf
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- 04/Jun/2010
- Interview with Translational Oncongenomics Editor in Chief Dr Michael Spinella
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- 04/Jun/2010
- Interview with Cancer Informatics editorial board member Dr Jimmy T. Efird
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- 04/Jun/2010
- Interview with Journal of Cell Death editorial board member Dr Hardy Kornfeld
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- 04/Jun/2010
- Interview with Journal of Cell Death editorial board member Dr Bruce S. Bochner
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- 03/Jun/2010
- Interview with Cancer Informatics editorial board member Dr Bradley J Erickson
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- 03/Jun/2010
- Biomarker Insights Editor in Chief co-author of Nature cover story
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- 06/May/2010
- Author interview with Dr Esther Uña Cidón
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- 26/Apr/2010
- Author interview with Dr Thomas Ostermann
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- 24/Mar/2010
- Author interview with Dr Yoshihito Yokoyama
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- 11/Mar/2010
Latest articles
- Muscle Functions in Polymyalgia Rheumatica and Giant-Cell Arteritis
- Empyema Thoracis
- Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes After Zinc and Anti-oxidant Therapy
- Insights into Protein Sequence and Structure-Derived Features Mediating 3D Domain Swapping Mechanism using Support Vector Machine Based Approach
- Utility of 4,5-Diphenylimidazol-2-thione in Synthesis of Fused Heterocyclic Ring Systems with Biological Interest
- Molecular Phylogeny of Edge Hill Virus Supports its Position in the Yellow Fever Virus Group and Identifies a New Genetic Variant
- Safety and Efficacy of Levonorgestrel 0.10 mg and Ethinyl Estradiol 0.02 mg Plus Ethinyl Estradiol 0.01 mg in an Extended-Cycle Oral Contraceptive Regimen
- Detection of Amide and Aromatic Proton Resonances of Human Brain Metabolites Using Localized Correlated Spectroscopy Combined with Two Different Water Suppression Schemes
- Fospropofol Disodium for Procedural Sedation: Emerging Evidence of its Value?
- Differential Human Plasma Proteomics Based on AniBal Quantification and Peptide-level Off-Gel Isoelectric Focussing
- Role of Metabolic Modulation in the Management of Chronic Ischemic Heart Disease
- Cellular Phone-Based Image Acquisition and Quantitative Ratiometric Method for Detecting Cocaine and Benzoylecgonine for Biological and Forensic Applications (Provisional PDF)
- Effectiveness and Safety of Rizatriptan Benzoate 10 mg in the Treatment of Migraine Headaches
- Editorial ISTRY Special Issue
- On the Biological Importance of the 3-hydroxyanthranilic Acid: Anthranilic Acid Ratio
- Accelerated Tryptophan Degradation Predicts Poor Survival in Trauma and Sepsis Patients
- Serum Levels of Tryptophan, 5-Hydroxytryptophan and Serotonin in Patients Affected with Different Forms of Amenorrhea
- Indoleamine 2,3-Dioxygenase in Human Hematopoietic Stem Cell Transplantation
- Proteasomal Degradation of Indoleamine 2,3-Dioxygenase in CD8+ Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3)
- Effects of Acute Tryptophan Depletion on Three Different Types of Behavioral Impulsivity
Most read articles
- Current Status of Monocyte Differentiation-Inducing (MDI) Factors Derived from Human Fetal Membrane Chorion Cells Undergoing Apoptosis after Influenza Virus Infection
- Relationship Between the Plasma Concentration of C-Reactive Protein and Severity of Peripheral Arterial Disease
- Intraspecific ITS Variability in the Kingdom Fungi as Expressed in the International Sequence Databases and Its Implications for Molecular Species Identification
- Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms
- A Simple Derivation of the Distribution of Pairwise Local Protein Sequence Alignment Scores
- DICOM Structured Reporting and Cancer Clinical Trials Results
- Mammoth and Elephant Phylogenetic Relationships: Mammut Americanum, the Missing Outgroup
- Evaluation of Two Outlier-Detection-Based Methods for Detecting Tissue-Selective Genes from Microarray Data
- Exploring the Evolutionary History of the Differentially Expressed Genes between Human Populations: Action of Recent Positive Selection
- Systems Biology-Based Identification of Crosstalk between E2F Transcription Factors and the Fanconi Anemia Pathway
- On the Adaptive Design Rules of Biochemical Networks in Evolution
- Phylogenetic diversity (PD) and biodiversity conservation: some bioinformatics challenges
- Identification and Quantitation of Asparagine and Citrulline Using High-Performance Liquid Chromatography (HPLC)
- Fast Genes and Slow Clades: Comparative Rates of Molecular Evolution in Mammals
- In Silico Promoter Analysis can Predict Genes of Functional Relevance in Cell Proliferation: Validation in a Colon Cancer Model
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Kentaro Murakami1, Satoshi Sasaki1, Yoshiko Takahashi2, Hitomi Okubo3, Naoko Hirota4, Akiko Notsu5, Mitsuru Fukui6 and Chigusa Date7 1Department of Social and Preventive Epidemiology, School of Public Health, the University of Tokyo, Tokyo, Japan. 2Department of Health and Nutrition, School of Home Economics, Wayo Women’s University, Chiba, Japan. 3Department of...
Over the recent years there has been a gradual rise in the use of pharmaceuticals during pregnancy. Knowledge on placental drug transfer and metabolism has increased during the past decades as well. Investigation of the transplacental transfer of any therapeutically useful drug is essential to the understanding of its metabolic...
Laura Kennedy1, J. Keith Vass1, D. Ross Haggart1, Steve Moore1, Michael E. Burczynski2, Dan Crowther1 and Gino Miele1 1Translational Medicine Research Collaboration Laboratory, Sir James Black Centre, University of Dundee, Dundee, DD1 5EH, U.K. 2Biomarker Laboratory, Wyeth Research, Collegeville, U.S.A. Abstract Peripheral blood as a surrogate tissue...
Environmental Health Research Involving Human Subjects: Ethical Issues (14/Jul/2008)
David B. Resnik Bioethicist National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC. Abstract This article reviews some of the ethical issues that arise in environmental health research with human subjects, such as minimizing risks to subjects, balancing benefits and risks in...
A Standards based Ontological Approach to Information Handling for use by Organizations Providing Human Tissue for Research (10/Apr/2008)
Mary E. Edgerton1, Carl Morrison2, Virginia A. LiVolsi3, Christopher A. Moskaluk4, Stephen J. Qualman5, M. Kay Washington6 and William E. Grizzle7 1Department of Pathology and Laboratory Medicine, University of Texas, M.D. Anderson Cancer Center, Houston, TX. 2Department of Pathology, The Ohio State University Hospitals, Columbus, OH. 3Department of Pathology...
Sample Preparation for in vitro Analysis of Iodine in Thyroid Tissue using X-ray Fluorescence (10/Apr/2008)
Marie Hansson1, Mats Isaksson1 and Gertrud Berg2 1Department of Radiation Physics, Göteborg University, Göteborg, Sweden. 2Department of Oncology, Sahlgrenska University Hospital, Göteborg, Sweden. Abstract Iodine is enriched and stored in the thyroid gland. Due to several factors, the size of the thyroid iodine pool varies both between individuals...
An Application of a Service-oriented System to Support ArrayAnnotation in Custom Chip Design for Epigenomic Analysis (10/Apr/2008)
Junghee Han, Dustin Potter, Tahsin Kurc, Greg Singer, Pearlly S. Yan, Sun Hao, Shannon Hastings, Stephen Langella, Scott Oster, Ramana V. Davuluri,Tim H.-M. Huang and Joel H. Saltz Department of Biomedical Informatics and Department of Molecular Virology, Immunology, and Medical Genetics The Ohio State University Columbus, OH, U.S.A....
An Application of a Service-oriented System to Support ArrayAnnotation in Custom Chip Design for Epigenomic Analysis (10/Apr/2008)
Junghee Han, Dustin Potter, Tahsin Kurc, Greg Singer, Pearlly S. Yan, Sun Hao, Shannon Hastings, Stephen Langella, Scott Oster, Ramana V. Davuluri,Tim H.-M. Huang and Joel H. Saltz Department of Biomedical Informatics and Department of Molecular Virology, Immunology, and Medical Genetics The Ohio State University Columbus, OH, U.S.A....
MCAM: A Database to Accelerate the Identification of Functional Cell Adhesion Molecules (31/Mar/2008)
Anguraj Sadanandam1, Sudipendra Nath Pal2, Joe Ziskovsky2, Prathibha Hegde2 and Rakesh K. Singh1 1Department of Pathology and Microbiology, 2Information Technology Services Learning Environment/Internet Services, University of Nebraska Medical Center, Omaha, NE, U.S.A. Abstract In the post-genomic era, computational identification of cell adhesion molecules (CAMs) becomes important in defining...
Ontologies for Bioinformatics (12/Mar/2008)
Nadine Schuurman and Agnieszka Leszczynski Department of Geography, Simon Fraser University RCB 7123, 8888 University Drive, Burnaby, British Columbia, Canada, V5A 1S6. Abstract The past twenty years have witnessed an explosion of biological data in diverse database formats governed by heterogeneous infrastructures. Not only are semantics (attribute terms)...
Feasibility of Ecological Momentary Assessment Using Cellular Telephones in Methamphetamine Dependent Subjects (10/Feb/2008)
Gantt P. Galloway, Ryne Didier, Kathleen Garrison and John Mendelson Addiction Pharmacology Research Laboratory, California Pacific Medical Center, San Francisco, CA 94110, U.S.A. Abstract Background: Predictors of relapse to methamphetamine use are poorly understood. State variables may play an important role in relapse, but they have been...
Ivy F.L. Tsui, Raj Chari, Timon P.H. Buys and Wan L. Lam Cancer Genetics and Developmental Biology, British Columbia Cancer Research Centre, and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada. Abstract The study of pathway disruption is key to...
Ivo P. Janecka Health Research International Boston, MA. Abstract Background: Colon cancer is among the leading causes of cancer mortality and its incidence is increasing worldwide. This is true in spite of broad basic research into colon cancer while, concurrently, physical activity has...
Joyce Xiuweu-Xu Gu1, Michael Yang Wei1, Pulivarthi H. Rao1, Ching C. Lau1, Sanjiv Behl2 and Tsz-Kwong Man1 1Department of Pediatrics, Baylor College of Medicine and Texas Children’s Cancer Center, Houston, Texas. 2Department of Computer Science, University of Houston, Victoria, Texas.Abstract: With the increasing application of various genomic technologies in biomedical...
Decentralized Data Sharing of Tissue Microarrays for Investigative Research in Oncology (06/Jun/2007)
Wenjin Chen1, Cristina Schmidt2, Manish Parashar2, Michael Reiss3,and David J. Foran1,31Center for Biomedical Imaging & Informatics, UMDNJ–Robert Wood Johnson Medical School. 2The Applied Systems Software Laboratory, Department of Electrical and Computer Engineering, Rutgers University. 3The Cancer Institute of New Jersey, UMDNJ–Robert Wood Johnson Medical School.Abstract: Tissue microarray technology (TMA) is...
Development of Query Strategies to Identify a Histologic Lymphoma Subtype in a Large Linked Database System (04/May/2007)
Michael Graiser1, Susan G. Moore1, Rochelle Victor1, Ashley Hilliard1, Leroy Hill1, Michael S. Keehan2 and Christopher R. Flowers11Emory University School of Medicine, Winship Cancer Institute, Oncology Informatics, 1365 Clifton Road, N.E., Atlanta, GA, U.S.A. 2NuTec Health Systems, LaGrange, TX, U.S.A.AbstractBackground: Large linked databases (LLDB) represent a novel resource for cancer...
Exploratory Visual Analysis of Statistical Results from Microarray Experiments Comparing High and Low Grade Glioma (01/Apr/2007)
David M. Reif1, Mark A. Israel2 and Jason H. Moore3 1Graduate Student, Computational Genetics Laboratory, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756. 2Professor of Pediatrics and Genetics, Director, Norris-Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756. 3Frank Lane Research Scholar in Computational Genetics, Associate Professor of Genetics, 706 Rubin Building...
Fiona Reddington1, J. Max Wilkinson1, Robin Clark1, Helen Parkinson2, Peter Kerr3and Richard Begent1 1NCRI Informatics Initiative, London, U.K. 2Formerly of the NCRI Informatics Initiative, now EBI, Hinxton, U.K. 3Formerly of the NCRI Informatics Initiative, now Almac Diagnostics, Craigavon, U.K.Abstract: The arrival of high-throughput technologies in cancer science and medicine has...
Heterogeneous Biomedical Database Integration Using a Hybrid Strategy: A p53 Cancer Research Database (20/Feb/2007)
Vadim Y. Bichutskiy1,7, Richard Colman7, Rainer K. Brachmann3,4,5,6,7 and Richard H. Lathrop1,2,71Department of Computer Science. 2Department of Biomedical Engineering. 3Department of Medicine. 4Department of Biological Chemistry. 5Department of Pathology. 6Division of Hematology/Oncology. 7Institute for Genomics and Bioinformatics, University of California, Irvine, California 92697, U.S.A.Abstract: Complex problems in life science research...
Fast Structural Search in Phylogenetic Databases (20/Feb/2007)
Jason T. L. Wang1, Huiyuan Shan2, Dennis Shasha3 and William H. Piel4 1Department of Computer Science, New Jersey Institute of Technology, University Heights, Newark, NJ, USA; 2Department of Computer Science, New Jersey Institute of Technology, University Heights, Newark, NJ, USA; 3Courant Institute of Mathematical Sciences, New York University, New York,...
Challenges in the Analysis of Mass-Throughput Data: A Technical Commentary from the Statistical Machine Learning Perspective (16/Feb/2007)
Constantin F. Aliferis1,2, Alexander Statnikov1 and Ioannis Tsamardinos11Discovery Systems Laboratory, Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA. 2Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA.Abstract: Sound data analysis is critical to the success of modern molecular medicine research that involves collection and interpretation of mass-throughput data. The...
Databases and QSAR for Cancer Research (15/Feb/2007)
Adeel Malik, Hemajit Singh, Munazah Andrabi, Syed Akhtar Husain and Shandar Ahmad Department of Biosciences, Jamia Millia Islamia University, New Delhi-110025, India.Abstract: In this review, we take a survey of bioinformatics databases and quantitative structure-activity relationship studies reported in published literature. Databases from the most general to special cancer-related ones...
PubMed QUEST: The PubMed Query Search Tool. An informatics tool to aid cancer centers and cancer investigators in searching the PubMed databases (12/Feb/2007)
David A. Hanauer1,3, Arul M. Chinnaiyan2,3 1Department of Pediatrics, 2Department of Pathology, 3Comprehensive Cancer Center Bioinformatics Core, University of Michigan Medical School, Ann Arbor, MI 48109, USAAbstract: Searching PubMed for citations related to a specific cancer center or group of authors can be labor-intensive. We have created a tool, PubMed...
Bioinformatics resources for cancer research with an emphasis on gene function and structure prediction tools (07/Feb/2007)
Daisuke Kihara1,2,3,4, Yifeng David Yang1 & Troy Hawkins11Department of Biological Sciences; 2Department of Computer Science; 3Markey Center for Structural Biology; 4The Bindley Bioscience Center, College of Science, Purdue University, West Lafayette, IN, 47907, USAAbstract: The immensely popular fields of cancer research and bioinformatics overlap in many different areas, e.g. large...


