Lipids
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Journal: Lipid Insights
Journal: Indian Journal of Clinical Medicine
Pharmacotherapy of Mixed Hyperlipidemia with Ezetimibe–Fenofibrate Combination Therapy (14/Jan/2010)
Mixed hyperlipidemia is a frequent atherogenic dyslipidemia characterized by elevated triglycerides, low HDL cholesterol levels, and excess of small, dense LDL particles, often with elevated apolipoproteinB and non-HDL cholesterol concentrations. Although statins are the drug of first choice, many high-risk patients with mixed hyperlipidemia do not achieve the recommended goals...
Rita K. Upmacis Center of Vascular Biology, Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065. Abstract Atherosclerosis, a disease characterized by plaque formation in the arterial wall that can lead to heart attack and stroke, is a principal...
C. elegans: A Model for Understanding Lipid Accumulation (13/Oct/2008)
Ida C. Elle, Louise C.B. Olsen, Mai-Britt Mosbech, Steven V. Rødkær, Dennis Pultz, Sanne G. Boelt, Julius Fredens, Pernille Sørensen and Nils Joakim Færgeman Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark. Abstract Regulation and coordination of lipid metabolism involve...
The Emerging Role of Eicosapentaenoic Acid as an Important Psychoactive Natural Product: Some Answers but a Lot more Questions (03/Oct/2008)
Brian M. Ross Division of Medical Science, Northern Ontario School of Medicine and the Departments of Biology, Chemistry and the Public Health Program, Lakehead University, Thunder Bay, Ontario, Canada. Abstract Omega-3 polyunsaturated fatty acids play important roles in both the structure and communication processes of cells. Dietary...
Sophisticated Functions for a Simple Molecule: The Role of Glucosylceramides in Fungal Cells (10/Sep/2008)
Leonardo Nimrichter1, Marcio L. Rodrigues1, Eliana Barreto-Bergter1 and Luiz R. Travassos2 1Instituto de Microbiologia Professor Paulo de Góes, Universidade Federal do Rio de Janeiro, 21941-590, Brazil. 2Unidade de Oncologia Experimental and Disciplina de Biologia Celular, Universidade Federal de São Paulo; São Paulo, SP 04023-062, Brazil. Abstract It...
Gender Differences in Musculoskeletal Lipid Metabolism as Assessed by Localized Two-Dimensional Correlation Spectroscopy (03/Sep/2008)
S. Sendhil Velan1,6, Nicholas Said1, Kartik Narasimhan1, Cyrus Papan2, Ali Bahu1, John Austin Vargo1, Raymond R. Raylman1, M. Albert Thomas3, Vazhaikkurichi M. Rajendran4, Richard G. Spencer5 and Stephen E. Alway6 1Center for Advanced Imaging and Department of Radiology, 4Departments of Medicine, Microbiology and Immunology, 6Department of Exercise Physiology, West...
Organization of Lipid Molecules within Biomembranes (02/Sep/2008)
M. Benhamou LPPPC, Physics Department, Sciences Faculty Ben M’sik P.O. 7955, Casablanca, Morocco. Abstract In this review, we report on the organization of lipid molecules forming biomembranes. More precisely, the question is how these amphiphiles phase separate under a change of a suitable parameter, like temperature, pressure...
Lipid Phases Eye View to Lipofection. Cationic Phosphatidylcholine Derivatives as Efficient DNA Carriers for Gene Delivery (28/Aug/2008)
Rumiana Koynova Northwestern University, Evanston, IL, U.S.A. Abstract Efficient delivery of genetic material to cells is needed for tasks of utmost importance in laboratory and clinic, such as gene transfection and gene silencing. Synthetic cationic lipids can be used as delivery vehicles for nucleic acids and are now...
José-Luis Pérez-Castrillón1,4, Manuel Gonzalez-Sagrado2,4, Marta Gonzalez-Rozas1, Maria Andres-Calvo1, Elena Izquierdo-Delgado1, Marcelino Mendo3, Daniel de Luis2,4 and Antonio Dueñas-Laita1 1Department of Medicine, University Hospital Rio Hortega University of Valladolid, Spain. 2Research Unit, University Hospital Rio Hortega University of Valladolid, Spain. 3Department of Radiology, University Hospital Rio Hortega University of Valladolid,...
Vesa M. Olkkonen National Public Health Institute and FIMM, Institute for Molecular Medicine Finland, Biomedicum, Helsinki, Finland. Abstract Oxysterols are naturally occurring oxidized derivatives of cholesterol, or by-products of cholesterol biosynthesis, with multiple biologic functions. These compounds display cytotoxic, pro-apoptotic, and pro-inflammatory activities and may play a...
G. Márquez-Ruiz, M.C. García-Martínez and F. Holgado Instituto del Frío (CSIC), José Antonio Novais 10, 28040 Madrid. Abstract This paper is focused on the present state-of-the art of modifications and effects of dietary oxidized lipids during their transit along the gastrointestinal tract. A survey of the literature...
Introductory Editorial (Lipid Insights) (27/Mar/2008)
Tim Levine Department of Cell Biology, UCL Institute of Ophthalmology, London, U.K.