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  • Author interview with Dr Shailesh Gupta
  • - 21/Jun/2010
  • Interview with Biomarker Insights editorial board member Dr William CS Cho
  • - 18/Jun/2010
  • Interview with Biomarkers in Cancer editorial board member Dr Xiaofeng Zhou
  • - 18/Jun/2010
  • Interview with Microbiology Insights editorial board member Dr Viroj Wiwanitkit
  • - 18/Jun/2010
  • Interview with Cell & Tissue Transplantation & Therapy editorial board member Dr Terje Forslund
  • - 17/Jun/2010
  • Interview with Nutrition and Metabolic Insights editorial board member Prof.Abdulaziz I.AL-Othaimeen
  • - 17/Jun/2010
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  • - 16/Jun/2010
  • Interview with Immunology and Immunogenetics Insights editorial board member Dr Robert Yarchoan
  • - 16/Jun/2010
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  • - 15/Jun/2010
  • Interview with Cancer Informatics editorial board member Dr Philip Crooke
  • - 15/Jun/2010
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  • - 15/Jun/2010
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  • - 26/Apr/2010
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Journal: Cell Biology Insights

Editor in Chief: Jianping Xu   |   Table of contents   |   23126 views
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Abstract
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The Evolution of Cell Communication: The Road not Taken     (09/Sep/2009)


In the post-genomic era the complex problem of evolutionary biology can be tackled from the top-down, the bottom-up, or from the middle-out. Given the emergent and contingent nature of this process, we have chosen to take the latter approach, both as a mechanistic link to developmental biology and as a...


Article: TGF-β1 -Induced Expression of the Anti-Apoptotic PAI-1 Protein Requires EGFR Signaling
Full-text PDFAbstract

TGF-β1 -Induced Expression of the Anti-Apoptotic PAI-1 Protein Requires EGFR Signaling     (11/Jun/2009)


TGF-β1 and its target gene encoding plasminogen activator inhibitor-1 (PAI-1) are major regulators of capillary outgrowth, vessel maturation and angiogenic network stability. The increasing realization of the complexity of PAI-1 action in the vascular system requires analysis of specific signaling events that impact its expression in a physiologically-relevant cell system. PAI-1 was required for tubular differentiation and maintenance of cellular survival in complex gels since targeted disruption of PAI-1 synthesis or activity with antisense constructs...


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Organization of Lipid Molecules within Biomembranes     (02/Sep/2008)


M. Benhamou LPPPC, Physics Department, Sciences Faculty Ben M’sik P.O. 7955, Casablanca, Morocco. Abstract In this review, we report on the organization of lipid molecules forming biomembranes. More precisely, the question is how these amphiphiles phase separate under a change of a suitable parameter, like temperature, pressure...


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Vesicular Trans-Cell Wall Transport in Fungi: A Mechanism for the Delivery of Virulence-Associated Macromolecules?     (25/Aug/2008)


Marcio L. Rodrigues1, Leonardo Nimrichter1, Debora L. Oliveira1, Joshua D. Nosanchuk2,3 and Arturo Casadevall2,3 1Laboratório de Estudos Integrados em Bioquímica Microbiana, Instituto de Microbiologia Professor Paulo de Góes, Universidade Federal do Rio de Janeiro, 21941590, Brazil. 2Department of Microbiology and Immunology and the 3Division of Infectious Diseases of the...


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A Salt-Threshold Required for Exacerbating Insulin Resistance in Dahl Salt-Sensitive (S) Rats     (20/Aug/2008)


The Dahl salt-sensitive (S) rat is a model of genetically determined salt-sensitivity and insulin resistance. In fact, insulin resistance is an inherited genetic trait that precedes and eventually co-exists with salt-sensitive hypertension in Dahl S, but not salt-resistant (R) Dahl rats. Owing to the critical role of salt in accelerating...


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The Toxicity of a Chemically Synthesized Peptide Derived from Non-Integrin Platelet Collagen Receptors     (13/Aug/2008)


A chemically synthesized peptide derived from platelet non-integrin collagen receptor has been shown to be an effective agent for inhibiting collagen-induced platelet aggregation and adhesion of washed radiolabeled platelets onto natural matrices and collagen coated microtiter plates. In order to be a therapeutic agent, we have used a cell culturing...


Abstract
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New Functions for Oxysterols and Their Cellular Receptors     (28/Jun/2008)


Vesa M. Olkkonen National Public Health Institute and FIMM, Institute for Molecular Medicine Finland, Biomedicum, Helsinki, Finland. Abstract Oxysterols are naturally occurring oxidized derivatives of cholesterol, or by-products of cholesterol biosynthesis, with multiple biologic functions. These compounds display cytotoxic, pro-apoptotic, and pro-inflammatory activities and may play a...


Abstract
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Introductory Editorial (Cell Biology Insights)     (04/Mar/2008)


Introductory Editorial by Dr Jianping Xu, Department of Biology, McMaster University, Hamilton, Ontario, Canada.