ETS-FUSions Networking, Triggering and Beyond
Authors: Yue Zhang
Publication Date: 04 Feb 2010
Genetics & Epigenetics 2010:3 1-4
Yue Zhang
Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Abstract
Gene fusion is a hallmark of cancer development with the mechanisms underlying their genesis emerging. The Staege and Max paper together with another recent paper have provided a comprehensive first view on current TET-ETS translocation studies. This significance, the trigering of gene fusion and beyond will be discussed in this article.
Keywords: gene fusion, TET-ETS, networking, cell signaling, target gene, triggering, cancer stem cell, epigenetics, ncRNA
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