Journal of Experimental Neuroscience
Synopsis: An open access, peer reviewed electronic journal that covers nervous system structure and function.
Indexing: Indexed by OAIster. Pubmed indexing for NIH-funded research.
Processing time: Decision in 3 weeks for 95% of papers.
Visibility: Most popular article read 400+ times.
Articles published in this journal at no charge for a limited time. Learn more and register here.
Anatomical and Functional Organization of Inhibitory Circuits in the Songbird Auditory Forebrain
Jin Kwon Jeong, Liisa A. Tremere, Michael J. Ryave, Victor C. Vuong and Raphael Pinaud
Department of Brain and Cognitive Sciences, University of Rochester, Rochester, NY, USA 14627.
Abstract
Recent studies on the anatomical and functional organization of GABAergic networks in central auditory circuits of the zebra finch have highlighted the strong impact of inhibitory mechanisms on both the central encoding and processing of acoustic information in a vocal learning species. Most of this work has focused on the caudomedial nidopallium (NCM), a forebrain area postulated to be the songbird analogue of the mammalian auditory association cortex. NCM houses neurons with selective responses to conspecific songs and is a site thought to house auditory memories required for vocal learning and, likely, individual identification. Here we review our recent work on the anatomical distribution of GABAergic cells in NCM, their engagement in response to song and the roles for inhibitory transmission in the physiology of NCM at rest and during the processing of natural communication signals. GABAergic cells are highly abundant in the songbird auditory forebrain and account for nearly half of the overall neuronal population in NCM with a large fraction of these neurons activated by song in freely-behaving animals. GABAergic synapses provide considerable local, tonic inhibition to NCM neurons at rest and, during sound processing, may contain the spread of excitation away from un-activated or quiescent parts of the network. Finally, we review our work showing that GABAA-mediated inhibition directly regulates the temporal organization of song-driven responses in awake songbirds, and appears to enhance the reliability of auditory encoding in NCM.
Readers of this also read:
- Anatomical and Functional Organization of Inhibitory Circuits in the Songbird Auditory Forebrain
- Tigecycline in the Treatment of Community-Acquired Pneumonia
- Present and Prospective Pharmacotherapies in Pulmonary Arterial Hypertension
- Collaboration to Meet a Therapeutic Need: The Development of Nelarabine
- Plasma Protein Profiles Differ Between Women Diagnosed with Cervical Intraepithelial Neoplasia (CIN) 1 and 3
- 16/Sep/2009
Immunolocalization of Dynamin I Protein in Projection Neurons of the Visual System of the Adult Cat
- 24/Jul/2009
Synaptic Mechanisms of Activity-Dependent Remodeling in Visual Cortex During Monocular Deprivation
- 08/Jul/2009
Grading Gradients: Evaluating Evidence for Time-dependent Memory Reorganization in Experimental Animals
- 28/Apr/2009
Neurosteroid Biosynthesis and Action in the Purkinje Cell
- 22/Apr/2009
Introductory Editorial (Journal of Experimental Neuroscience)
- 01/Aug/2008
Journal of Experimental Neuroscience
Raphael Pinaud, Editor in Chief
Submit a paper
 |
|
 |
YAHOO! BUZZ |
 |
DIGG |
 |
|
 |
MIXX |
 |
PERMALINK |
 |
GOOGLE BOOKMARKS |
 |
DELICIOUS |
 |
|
 |
NEWSVINE |
Interview with Cancer Informatics editorial board member Dr Grant Izmirlian - 22/Sep/2009
Call for papers for Analytical Chemistry Insights from Dr Gabor Patonay - 22/Sep/2009
Sponsor the IBM-OCI Integrative Discovery team in Ride to Conquer Cancer - 15/Sep/2009
No article processing fees for selected journals - 25/Sep/2009
Newsletter summary (week 36, 2009) - 15/Sep/2009
Interview with Healthy Aging and Clinical Care in the Elderly editorial board member Dr Davide Malatesta - 15/Sep/2009
Interview with Translational Oncogenomics author Dr David Frank - 10/Sep/2009
Interview with Retrovirology: Research and Treatment author Dr Elcio Leal - 10/Sep/2009
Interview with Microbiology Insights author Dr Tinatin Doolotkedlieva - 10/Sep/2009
Call for papers for Drug Target Insights by Dr Monica Milani - 10/Sep/2009
Call for papers for Clinical Medicine: Urology from Dr Xiangyi Lu - 10/Sep/2009
Research profile on Gene Regulation and Systems Biology author Dr Noboru Uchide - 09/Sep/2009
Interview with Biomarker Insights editorial board member Dr Lawrence Cheskin - 07/Sep/2009
Newsletter summary (week 35, 2009) - 04/Sep/2009
Research profile of Clinical Medicine: Endocrinology and Diabetes author Dr Hiro Koshiyama - 04/Sep/2009
Open access articles published in August - 03/Sep/2009
Call for papers for Clinical Medicine: Circulatory, Respiratory and Pulmonary Medicine from Dr Hussein Foda - 03/Sep/2009
Interview with Cancer Informatics editorial board member Dr Georgios S. Stamatakos - 03/Sep/2009
Announcing mobile Libertas Academica website - 02/Sep/2009
Effects of Kynurenine Pathway Metabolites on Intracellular NAD+ Synthesis and Cell Death in Human Primary Astrocytes and Neurons - 03/Apr/2009
Production and Peripheral Roles of 5-HTP, a Precursor of Serotonin - 30/Mar/2009
L -Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications - 23/Mar/2009
Dedication: Paolo Guidetti - 16/Feb/2009
Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model - 14/Jan/2009
Kynurenine Pathway Metabolites in Humans: Disease and Healthy States - 08/Dec/2008
Tryptophan Research in Panic Disorder - 14/Aug/2008
Introductory Editorial (International Journal of Tryptophan Research) - 09/Apr/2008