Evolutionary Bioinformatics
Synopsis: An open access, peer reviewed electronic journal that covers computational evolutionary biology and evolutionary bioinformatics.
Indexed by: Pubmed, Pubmed Central, CAS, DOAJ, Embase, Embiology, Science Citation Index Expanded (SciSearch®), Journal Citation Reports/Science Edition, Current Contents®/Agriculture, Biology and Environmental Sciences, Current Contents®/Life Sciences, Google Scholar, EBSCO Academic Search Complete, OAIster.
Visibility: Most popular article read 3200+ times.
Processing time: Decision in 2 weeks for 90% of papers.
Phylogenetic Analyses Reveal Monophyletic Origin of the Ergot Alkaloid Gene dmaW in Fungi
Authors: Miao Liu, Daniel G. Panaccione and Christopher L. Schardl
Publication Date: 04 Jun 2009
Evolutionary Bioinformatics 2009:5 15-30
Miao Liu1,3, Daniel G. Panaccione2 and Christopher L. Schardl1
1201 F Plant science Bldg. University of Kentucky, Lexington, KY 40546. 2Division of Plant and Soil Sciences, West Virginia University, PO Box 6108, Morgantown, WV 26506-6108. 3Biodiversity (Mycology and Botany), Eastern Cereal and Oilseed Research Centre, Agriculture and Agri-Food Canada, 960 Carling Avenue, Ottawa, Ontario K1A 0C6.
Abstract
Ergot alkaloids are indole-derived mycotoxins that are important in agriculture and medicine. Ergot alkaloids are produced by a few representatives of two distantly related fungal lineages, the Clavicipitaceae and the Trichocomaceae. Comparison of the ergot alkaloid gene clusters from these two lineages revealed differences in the relative positions and orientations of several genes. The question arose: is ergot alkaloid biosynthetic capability from a common origin? We used a molecular phylogenetic approach to gain insights into the evolution of ergot alkaloid biosynthesis. The 4-γ,γ-dimethylallyltryptophan synthase gene, dmaW, encodes the first step in the pathway. Amino acid sequences deduced from dmaW and homologs were submitted to phylogenetic analysis, and the results indicated that dmaW of Aspergillus fumigatus (mitosporic Trichocomaceae) has the same origin as corresponding genes from clavicipitaceous fungi. Relationships of authentic dmaW genes suggest that they originated from multiple gene duplications with subsequent losses of original or duplicate versions in some lineages.
Categories: Evolutionary bioinformatics
Keywords: mycotoxins, 4-γ,γ-dimethylallyltryptophan synthase gene, Clavicipitaceae, Trichocomaceae, amino acid sequence, GBlocks, gene phylogeny
Readers of this also read:
- Phylogenetic Analyses Reveal Monophyletic Origin of the Ergot Alkaloid Gene dmaW in Fungi
- A Comprehensive Analysis of Gene Expression Evolution Between Humans and Mice
- A Simple Derivation of the Distribution of Pairwise Local Protein Sequence Alignment Scores
- Phylogenetic Applications of the Minimum Contradiction Approach on Continuous Characters
- A Comprehensive Analysis of Gene Expression Evolution Between Humans and Mice
Sign up for free journal updates
Recently published in this journal 
Genome-Wide Identification and Evolutionary Analysis of the Animal Specific ETS Transcription Factor Family
- 02/Oct/2009
A Model for Protein Sequence Evolution Based on Selective Pressure for Protein Stability: Application to Hemoglobins
- 27/Aug/2009
On the Use of Bootstrapped Topologies in Coalescent-Based Bayesian MCMC Inference: A Comparison of Estimation and Computational Efficiencies
- 31/Jul/2009
PhyLIS: A Simple GNU/Linux Distribution for Phylogenetics and Phyloinformatics
- 30/Jul/2009
A Comprehensive Analysis of Gene Expression Evolution Between Humans and Mice
- 06/Jul/2009
Initial Implementation of a Comparative Data Analysis Ontology
- 03/Jul/2009
A Mixture Model and a Hidden Markov Model to Simultaneously Detect Recombination Breakpoints and Reconstruct Phylogenies
- 25/Jun/2009
Phylogenetic Applications of the Minimum Contradiction Approach on Continuous Characters
- 11/Jun/2009
Phylogenetic Analyses Reveal Monophyletic Origin of the Ergot Alkaloid Gene dmaW in Fungi
- 04/Jun/2009
Evolution and Functional Diversification of the GLI Family of Transcription Factors in Vertebrates
- 18/May/2009
REFGEN and TREENAMER: Automated Sequence Data Handling for Phylogenetic Analysis in the Genomic Era
- 06/May/2009
The Austronesian Basic Vocabulary Database: From Bioinformatics to Lexomics
- 03/Nov/2008
Evidence for a Complex Mosaic Genome Pattern in a Full-length Hepatitis C Virus Sequence
- 30/Oct/2008
Inconsistent Distances in Substitution Matrices can be Avoided by Properly Handling Hydrophobic Residues
- 09/Oct/2008
Bayesian, Maximum Parsimony and UPGMA Models for Inferring the Phylogenies of Antelopes Using Mitochondrial Markers
- 06/Oct/2008
Minimum Contradiction Matrices in Whole Genome Phylogenies
- 21/Jul/2008
Estimation of Genetic Effects and Genotype-Phenotype Maps
- 28/Jun/2008
Testing the Accuracy of Eukaryotic Phylogenetic Profiles for Prediction of Biological Function
- 18/Jun/2008
Electrostatic and Functional Analysis of the Seven-Bladed WD β-Propellers
- 13/Jun/2008
Intraspecific ITS Variability in the Kingdom Fungi as Expressed in the International Sequence Databases and Its Implications for Molecular Species Identification
- 26/May/2008
Exploring the Evolutionary History of the Differentially Expressed Genes between Human Populations: Action of Recent Positive Selection
- 15/May/2008
Maximum Gene-Support Tree
- 15/May/2008
Examining Ancient Inter-domain Horizontal Gene Transfer
- 09/May/2008
Strategies for Reliable Exploitation of Evolutionary Concepts in High Throughput Biology
- 08/May/2008
Dissection of Functional Residues in Receptor Activity-Modifying Proteins Through Phylogenetic and Statistical Analyses
- 28/Apr/2008
Assessing the Evolution of Gene Expression Using Microarray Data
- 24/Apr/2008
Identifying Coevolving Partners from Paralogous Gene Families
- 24/Apr/2008
The ABCs of MGR with DCJ
- 10/Apr/2008
Comparative Evolutionary Histories of the Fungal Chitinase Gene Family Reveal Non-Random Size Expansions and Contractions due to Adaptive Natural Selection
- 18/Mar/2008
Expected Anomalies in the Fossil Record
- 18/Mar/2008
How to Summarize Estimates of Ancestral Divergence Times
- 18/Mar/2008
A Simple Derivation of the Distribution of Pairwise Local Protein Sequence Alignment Scores
- 14/Feb/2008
Why Should We Care About Molecular Coevolution?
- 14/Feb/2008
Detecting Microsatellites in Genome Data: Variance in Definitions and Bioinformatic Approaches Cause Systematic Bias
- 09/Feb/2008
Reverse Conservation Analysis Reveals the Specificity Determining Residues of Cytochrome P450 Family 2 (CYP 2)
- 09/Feb/2008
SPR Distance Computation for Unrooted Trees
- 09/Feb/2008
Evolution of the Influenza A Virus: Some New Advances
- 30/Jan/2008
The 2006 NESCent Phyloinformatics Hackathon: A Field Report
- 14/Dec/2007
Phylogenetic Study of the Evolution of PEP-Carboxykinase
- 11/Dec/2007
Efficient Tree Searches with Available Algorithms
- 12/Nov/2007
Structural Evolution of the ABC Transporter Subfamily B
- 08/Nov/2007
An Insulin-Like Modular Basis for the Evolution of Glucose Transporters (GLUT) with Implications for Diabetes
- 15/Oct/2007
Minimizing Contradictions on Circular Order of Phylogenic Trees
- 11/Oct/2007
Selection Effects on the Positioning of Genes and Gene Structures from the Interplay of Replication and Transcription in Bacterial Genomes
- 09/Oct/2007
Phylogenomic Analysis Reveals Extensive Phylogenetic Mosaicism in the Human GPCR Superfamily
- 26/Sep/2007
Non-Molecular-Clock-Like Evolution following Viral Origins in Homo sapiens
- 26/Sep/2007
Underlying Principles of Natural Selection in Network Evolution: Systems Biology Approach
- 26/Sep/2007
Hedging Our Bets: The Expected Contribution of Species to Future Phylogenetic Diversity
- 25/Sep/2007
Genome Signatures, Self-Organizing Maps and Higher Order Phylogenies: A Parametric Analysis
- 17/Sep/2007
The GC Skew Index: A Measure of Genomic Compositional Asymmetry and the Degree of Replicational Selection
- 06/Sep/2007
Interactions Between SNP Alleles at Multiple Loci and Variation in Skin Pigmentation in 122 Caucasians
- 06/Sep/2007
Identifcation of Novel Retroid Agents in Danio rerio, Oryzias latipes, Gasterosteus aculeatus and Tetraodon nigroviridis
- 06/Sep/2007
Gathering Computational Genomics and Proteomics to Unravel Adaptive Evolution
- 06/Sep/2007
Prediction of Protein-protein Interactions on the Basis of Evolutionary Conservation of Protein Functions
- 08/Aug/2007
Characterization and Evolution of the Cell Cycle-Associated Mob Domain-Containing Proteins in Eukaryotes
- 08/Aug/2007
Environmental Quality, Developmental Plasticity and the Thrifty Phenotype: A Review of Evolutionary Models
- 19/Jun/2007
Choosing and Using Introns in Molecular Phylogenetics
- 14/Jun/2007
Fast Genes and Slow Clades: Comparative Rates of Molecular Evolution in Mammals
- 31/May/2007
A Reduction Algorithm for Computing The Hybridization Number of Two Trees
- 30/May/2007
An Improved Implementation of Codon Adaptation Index
- 17/May/2007
Mammoth and Elephant Phylogenetic Relationships: Mammut Americanum, the Missing Outgroup
- 29/Mar/2007
Mlcoalsim: Multilocus Coalescent Simulations
- 02/Mar/2007
Why Bacteriophage Encode Exotoxins and other Virulence Factors
- 28/Feb/2007
On the Adaptive Design Rules of Biochemical Networks in Evolution
- 28/Feb/2007
Improved Heuristics for Minimum-Flip Supertree Construction
- 28/Feb/2007
The identification of functional motifs in temporal gene expression analysis
- 27/Feb/2007
Outsourcing the Nucleus: Nuclear Pore Complex Genes are no Longer Encoded in Nucleomorph Genomes
- 27/Feb/2007
MySSP: Non-stationary evolutionary sequence simulation, including indels
- 26/Feb/2007
Topological Bias in Distance-Based Phylogenetic Methods: Problems with Over- and Underestimated Genetic Distances
- 26/Feb/2007
Estimation of Phylogeny Using a General Markov Model
- 25/Feb/2007
Pattern-Based Phylogenetic Distance Estimation and Tree Reconstruction
- 25/Feb/2007
Evolution of proteins and proteomes: a phylogenetics approach
- 24/Feb/2007
Multiple Property Tolerance Analysis for the Evaluation of Missense Mutations
- 24/Feb/2007
Arlequin (version 3.0): An integrated software package for population genetics data analysis
- 23/Feb/2007
ALFRED: An Allele Frequency Database for Microevolutionary Studies
- 22/Feb/2007
A Fast and Specific Alignment Method for Minisatellite Maps
- 22/Feb/2007
Phylogenetic biodiversity assessment based on systematic nomenclature
- 21/Feb/2007
Genome Halving with an Outgroup
- 21/Feb/2007
Fast Structural Search in Phylogenetic Databases
- 20/Feb/2007
Estimating the Relative Order of Speciation or Coalescence Events on a Given Phylogeny
- 20/Feb/2007
The Role of the Phylogenetic Diversity Measure, PD, in Bio-informatics: Getting the Definition Right
- 19/Feb/2007
Co-evolutionary Rates of Functionally Related Yeast Genes
- 18/Feb/2007
A Nuclear Ribosomal DNA Phylogeny of Acer Inferred with Maximum Likelihood, Splits Graphs, and Motif Analysis of 606 Sequences
- 17/Feb/2007
Phylogenetic diversity (PD) and biodiversity conservation: some bioinformatics challenges
- 17/Feb/2007
Minimum Conflict Individual Haplotyping from SNP Fragments and Related Genotype
- 16/Feb/2007
Gaussian Quadrature Formulae for Arbitrary Positive Measures
- 15/Feb/2007
Identification of Conflicting Selective Effects on Highly Expressed Genes
- 14/Feb/2007
MapToGenome: A Comparative Genomic Tool that Aligns Transcript Maps to Sequenced Genomes
- 14/Feb/2007
LASER: A Maximum Likelihood Toolkit for Detecting Temporal Shifts in Diversification Rates From Molecular Phylogenies
- 14/Feb/2007
Total Evidence, Average Consensus and Matrix Representation with Parsimony: What a Difference Distances Make
- 13/Feb/2007
Estimating Population Parameters using the Structured Serial Coalescent with Bayesian MCMC Inference when some Demes are Hidden
- 12/Feb/2007
Unravelling Selection Shifts Among Foot-and-Mouth Disease Virus (FMDV) Serotypes
- 11/Feb/2007
PIRSF Family Classification System for Protein Functional and Evolutionary Analysis
- 10/Feb/2007
Spectral Analysis of Sequence Variability in Basic-Helix-loop-helix (bHLH) Protein Domains
- 09/Feb/2007
CoMET: A Mesquite package for comparing models of continuous character evolution on phylogenies
- 07/Feb/2007
MBEToolbox 2.0: An enhanced version of a MATLAB toolbox for Molecular Biology and Evolution
- 06/Feb/2007
Modelling prokaryote gene content
- 05/Feb/2007
Assessing the Applicability of the GTR Nucleotide Substitution Model Through Simulations
- 04/Feb/2007
Using minimum bootstrap support for splits to construct confidence regions for trees
- 03/Feb/2007
A new effective method for estimating missing values in the sequence data prior to phylogenetic analysis
- 01/Feb/2007
- 02/Oct/2009
A Model for Protein Sequence Evolution Based on Selective Pressure for Protein Stability: Application to Hemoglobins
- 27/Aug/2009
On the Use of Bootstrapped Topologies in Coalescent-Based Bayesian MCMC Inference: A Comparison of Estimation and Computational Efficiencies
- 31/Jul/2009
PhyLIS: A Simple GNU/Linux Distribution for Phylogenetics and Phyloinformatics
- 30/Jul/2009
A Comprehensive Analysis of Gene Expression Evolution Between Humans and Mice
- 06/Jul/2009
Initial Implementation of a Comparative Data Analysis Ontology
- 03/Jul/2009
A Mixture Model and a Hidden Markov Model to Simultaneously Detect Recombination Breakpoints and Reconstruct Phylogenies
- 25/Jun/2009
Phylogenetic Applications of the Minimum Contradiction Approach on Continuous Characters
- 11/Jun/2009
Phylogenetic Analyses Reveal Monophyletic Origin of the Ergot Alkaloid Gene dmaW in Fungi
- 04/Jun/2009
Evolution and Functional Diversification of the GLI Family of Transcription Factors in Vertebrates
- 18/May/2009
REFGEN and TREENAMER: Automated Sequence Data Handling for Phylogenetic Analysis in the Genomic Era
- 06/May/2009
The Austronesian Basic Vocabulary Database: From Bioinformatics to Lexomics
- 03/Nov/2008
Evidence for a Complex Mosaic Genome Pattern in a Full-length Hepatitis C Virus Sequence
- 30/Oct/2008
Inconsistent Distances in Substitution Matrices can be Avoided by Properly Handling Hydrophobic Residues
- 09/Oct/2008
Bayesian, Maximum Parsimony and UPGMA Models for Inferring the Phylogenies of Antelopes Using Mitochondrial Markers
- 06/Oct/2008
Minimum Contradiction Matrices in Whole Genome Phylogenies
- 21/Jul/2008
Estimation of Genetic Effects and Genotype-Phenotype Maps
- 28/Jun/2008
Testing the Accuracy of Eukaryotic Phylogenetic Profiles for Prediction of Biological Function
- 18/Jun/2008
Electrostatic and Functional Analysis of the Seven-Bladed WD β-Propellers
- 13/Jun/2008
Intraspecific ITS Variability in the Kingdom Fungi as Expressed in the International Sequence Databases and Its Implications for Molecular Species Identification
- 26/May/2008
Exploring the Evolutionary History of the Differentially Expressed Genes between Human Populations: Action of Recent Positive Selection
- 15/May/2008
Maximum Gene-Support Tree
- 15/May/2008
Examining Ancient Inter-domain Horizontal Gene Transfer
- 09/May/2008
Strategies for Reliable Exploitation of Evolutionary Concepts in High Throughput Biology
- 08/May/2008
Dissection of Functional Residues in Receptor Activity-Modifying Proteins Through Phylogenetic and Statistical Analyses
- 28/Apr/2008
Assessing the Evolution of Gene Expression Using Microarray Data
- 24/Apr/2008
Identifying Coevolving Partners from Paralogous Gene Families
- 24/Apr/2008
The ABCs of MGR with DCJ
- 10/Apr/2008
Comparative Evolutionary Histories of the Fungal Chitinase Gene Family Reveal Non-Random Size Expansions and Contractions due to Adaptive Natural Selection
- 18/Mar/2008
Expected Anomalies in the Fossil Record
- 18/Mar/2008
How to Summarize Estimates of Ancestral Divergence Times
- 18/Mar/2008
A Simple Derivation of the Distribution of Pairwise Local Protein Sequence Alignment Scores
- 14/Feb/2008
Why Should We Care About Molecular Coevolution?
- 14/Feb/2008
Detecting Microsatellites in Genome Data: Variance in Definitions and Bioinformatic Approaches Cause Systematic Bias
- 09/Feb/2008
Reverse Conservation Analysis Reveals the Specificity Determining Residues of Cytochrome P450 Family 2 (CYP 2)
- 09/Feb/2008
SPR Distance Computation for Unrooted Trees
- 09/Feb/2008
Evolution of the Influenza A Virus: Some New Advances
- 30/Jan/2008
The 2006 NESCent Phyloinformatics Hackathon: A Field Report
- 14/Dec/2007
Phylogenetic Study of the Evolution of PEP-Carboxykinase
- 11/Dec/2007
Efficient Tree Searches with Available Algorithms
- 12/Nov/2007
Structural Evolution of the ABC Transporter Subfamily B
- 08/Nov/2007
An Insulin-Like Modular Basis for the Evolution of Glucose Transporters (GLUT) with Implications for Diabetes
- 15/Oct/2007
Minimizing Contradictions on Circular Order of Phylogenic Trees
- 11/Oct/2007
Selection Effects on the Positioning of Genes and Gene Structures from the Interplay of Replication and Transcription in Bacterial Genomes
- 09/Oct/2007
Phylogenomic Analysis Reveals Extensive Phylogenetic Mosaicism in the Human GPCR Superfamily
- 26/Sep/2007
Non-Molecular-Clock-Like Evolution following Viral Origins in Homo sapiens
- 26/Sep/2007
Underlying Principles of Natural Selection in Network Evolution: Systems Biology Approach
- 26/Sep/2007
Hedging Our Bets: The Expected Contribution of Species to Future Phylogenetic Diversity
- 25/Sep/2007
Genome Signatures, Self-Organizing Maps and Higher Order Phylogenies: A Parametric Analysis
- 17/Sep/2007
The GC Skew Index: A Measure of Genomic Compositional Asymmetry and the Degree of Replicational Selection
- 06/Sep/2007
Interactions Between SNP Alleles at Multiple Loci and Variation in Skin Pigmentation in 122 Caucasians
- 06/Sep/2007
Identifcation of Novel Retroid Agents in Danio rerio, Oryzias latipes, Gasterosteus aculeatus and Tetraodon nigroviridis
- 06/Sep/2007
Gathering Computational Genomics and Proteomics to Unravel Adaptive Evolution
- 06/Sep/2007
Prediction of Protein-protein Interactions on the Basis of Evolutionary Conservation of Protein Functions
- 08/Aug/2007
Characterization and Evolution of the Cell Cycle-Associated Mob Domain-Containing Proteins in Eukaryotes
- 08/Aug/2007
Environmental Quality, Developmental Plasticity and the Thrifty Phenotype: A Review of Evolutionary Models
- 19/Jun/2007
Choosing and Using Introns in Molecular Phylogenetics
- 14/Jun/2007
Fast Genes and Slow Clades: Comparative Rates of Molecular Evolution in Mammals
- 31/May/2007
A Reduction Algorithm for Computing The Hybridization Number of Two Trees
- 30/May/2007
An Improved Implementation of Codon Adaptation Index
- 17/May/2007
Mammoth and Elephant Phylogenetic Relationships: Mammut Americanum, the Missing Outgroup
- 29/Mar/2007
Mlcoalsim: Multilocus Coalescent Simulations
- 02/Mar/2007
Why Bacteriophage Encode Exotoxins and other Virulence Factors
- 28/Feb/2007
On the Adaptive Design Rules of Biochemical Networks in Evolution
- 28/Feb/2007
Improved Heuristics for Minimum-Flip Supertree Construction
- 28/Feb/2007
The identification of functional motifs in temporal gene expression analysis
- 27/Feb/2007
Outsourcing the Nucleus: Nuclear Pore Complex Genes are no Longer Encoded in Nucleomorph Genomes
- 27/Feb/2007
MySSP: Non-stationary evolutionary sequence simulation, including indels
- 26/Feb/2007
Topological Bias in Distance-Based Phylogenetic Methods: Problems with Over- and Underestimated Genetic Distances
- 26/Feb/2007
Estimation of Phylogeny Using a General Markov Model
- 25/Feb/2007
Pattern-Based Phylogenetic Distance Estimation and Tree Reconstruction
- 25/Feb/2007
Evolution of proteins and proteomes: a phylogenetics approach
- 24/Feb/2007
Multiple Property Tolerance Analysis for the Evaluation of Missense Mutations
- 24/Feb/2007
Arlequin (version 3.0): An integrated software package for population genetics data analysis
- 23/Feb/2007
ALFRED: An Allele Frequency Database for Microevolutionary Studies
- 22/Feb/2007
A Fast and Specific Alignment Method for Minisatellite Maps
- 22/Feb/2007
Phylogenetic biodiversity assessment based on systematic nomenclature
- 21/Feb/2007
Genome Halving with an Outgroup
- 21/Feb/2007
Fast Structural Search in Phylogenetic Databases
- 20/Feb/2007
Estimating the Relative Order of Speciation or Coalescence Events on a Given Phylogeny
- 20/Feb/2007
The Role of the Phylogenetic Diversity Measure, PD, in Bio-informatics: Getting the Definition Right
- 19/Feb/2007
Co-evolutionary Rates of Functionally Related Yeast Genes
- 18/Feb/2007
A Nuclear Ribosomal DNA Phylogeny of Acer Inferred with Maximum Likelihood, Splits Graphs, and Motif Analysis of 606 Sequences
- 17/Feb/2007
Phylogenetic diversity (PD) and biodiversity conservation: some bioinformatics challenges
- 17/Feb/2007
Minimum Conflict Individual Haplotyping from SNP Fragments and Related Genotype
- 16/Feb/2007
Gaussian Quadrature Formulae for Arbitrary Positive Measures
- 15/Feb/2007
Identification of Conflicting Selective Effects on Highly Expressed Genes
- 14/Feb/2007
MapToGenome: A Comparative Genomic Tool that Aligns Transcript Maps to Sequenced Genomes
- 14/Feb/2007
LASER: A Maximum Likelihood Toolkit for Detecting Temporal Shifts in Diversification Rates From Molecular Phylogenies
- 14/Feb/2007
Total Evidence, Average Consensus and Matrix Representation with Parsimony: What a Difference Distances Make
- 13/Feb/2007
Estimating Population Parameters using the Structured Serial Coalescent with Bayesian MCMC Inference when some Demes are Hidden
- 12/Feb/2007
Unravelling Selection Shifts Among Foot-and-Mouth Disease Virus (FMDV) Serotypes
- 11/Feb/2007
PIRSF Family Classification System for Protein Functional and Evolutionary Analysis
- 10/Feb/2007
Spectral Analysis of Sequence Variability in Basic-Helix-loop-helix (bHLH) Protein Domains
- 09/Feb/2007
CoMET: A Mesquite package for comparing models of continuous character evolution on phylogenies
- 07/Feb/2007
MBEToolbox 2.0: An enhanced version of a MATLAB toolbox for Molecular Biology and Evolution
- 06/Feb/2007
Modelling prokaryote gene content
- 05/Feb/2007
Assessing the Applicability of the GTR Nucleotide Substitution Model Through Simulations
- 04/Feb/2007
Using minimum bootstrap support for splits to construct confidence regions for trees
- 03/Feb/2007
A new effective method for estimating missing values in the sequence data prior to phylogenetic analysis
- 01/Feb/2007
Related journals...
Evolutionary Bioinformatics
Dennis Wall, Editor in Chief
Submit a paper
Share this journal
 |
|
 |
YAHOO! BUZZ |
 |
DIGG |
 |
|
 |
MIXX |
 |
PERMALINK |
 |
GOOGLE BOOKMARKS |
 |
DELICIOUS |
 |
|
 |
NEWSVINE |
Recent news
Open access articles published in September - 02/Oct/2009
Announcing the Indian Journal of Clinical Medicine - 30/Sep/2009
Autism Insights launched - 29/Sep/2009
Newsletter summary (week 37, 2009) - 25/Sep/2009
Interview with Clinical Medicine: Cardiology editorial board member Dr Vernon Barnes - 25/Sep/2009
Interview with Cancer Informatics editorial board member Dr Grant Izmirlian - 22/Sep/2009
Call for papers for Analytical Chemistry Insights from Dr Gabor Patonay - 22/Sep/2009
Sponsor the IBM-OCI Integrative Discovery team in Ride to Conquer Cancer - 15/Sep/2009
No article processing fees for selected journals - 25/Sep/2009
Newsletter summary (week 36, 2009) - 15/Sep/2009
Interview with Healthy Aging and Clinical Care in the Elderly editorial board member Dr Davide Malatesta - 15/Sep/2009
Interview with Translational Oncogenomics author Dr David Frank - 10/Sep/2009
Interview with Retrovirology: Research and Treatment author Dr Elcio Leal - 10/Sep/2009
Interview with Microbiology Insights author Dr Tinatin Doolotkedlieva - 10/Sep/2009
Call for papers for Drug Target Insights by Dr Monica Milani - 10/Sep/2009
Call for papers for Clinical Medicine: Urology from Dr Xiangyi Lu - 10/Sep/2009
Research profile on Gene Regulation and Systems Biology author Dr Noboru Uchide - 09/Sep/2009
Interview with Biomarker Insights editorial board member Dr Lawrence Cheskin - 07/Sep/2009
Newsletter summary (week 35, 2009) - 04/Sep/2009
Research profile of Clinical Medicine: Endocrinology and Diabetes author Dr Hiro Koshiyama - 04/Sep/2009
Announcing the Indian Journal of Clinical Medicine - 30/Sep/2009
Autism Insights launched - 29/Sep/2009
Newsletter summary (week 37, 2009) - 25/Sep/2009
Interview with Clinical Medicine: Cardiology editorial board member Dr Vernon Barnes - 25/Sep/2009
Interview with Cancer Informatics editorial board member Dr Grant Izmirlian - 22/Sep/2009
Call for papers for Analytical Chemistry Insights from Dr Gabor Patonay - 22/Sep/2009
Sponsor the IBM-OCI Integrative Discovery team in Ride to Conquer Cancer - 15/Sep/2009
No article processing fees for selected journals - 25/Sep/2009
Newsletter summary (week 36, 2009) - 15/Sep/2009
Interview with Healthy Aging and Clinical Care in the Elderly editorial board member Dr Davide Malatesta - 15/Sep/2009
Interview with Translational Oncogenomics author Dr David Frank - 10/Sep/2009
Interview with Retrovirology: Research and Treatment author Dr Elcio Leal - 10/Sep/2009
Interview with Microbiology Insights author Dr Tinatin Doolotkedlieva - 10/Sep/2009
Call for papers for Drug Target Insights by Dr Monica Milani - 10/Sep/2009
Call for papers for Clinical Medicine: Urology from Dr Xiangyi Lu - 10/Sep/2009
Research profile on Gene Regulation and Systems Biology author Dr Noboru Uchide - 09/Sep/2009
Interview with Biomarker Insights editorial board member Dr Lawrence Cheskin - 07/Sep/2009
Newsletter summary (week 35, 2009) - 04/Sep/2009
Research profile of Clinical Medicine: Endocrinology and Diabetes author Dr Hiro Koshiyama - 04/Sep/2009
Similar papers
Changes in Plasma IL-6, Plasma VEGF and Serum YKL-40 During Treatment with Etanercept and Methotrexate or Etanercept Alone in Patients with Active Rheumatoid Arthritis Despite Methotrexate Therapy - 29/Sep/2009
Graphical User Interfaces for Molecular Dynamics—Quo Vadis? - 23/Sep/2009
Gromita: A Fully Integrated Graphical User Interface to Gromacs 4 - 07/Sep/2009
Gene Expression Based Leukemia Sub‑Classification Using Committee Neural Networks - 03/Sep/2009
Unblocking Blockbusters: Using Boolean Text-Mining to Optimise Clinical Trial Design and Timeline for Novel Anticancer Drugs - 17/Aug/2009
New Advanced Technologies to Provide Decentralised and Secure Access to Medical Records: Case Studies in Oncology - 07/Aug/2009
Novel Biomarkers for the Diagnosis of Urinary Tract Infection - A Systematic Review - 05/Aug/2009
The Bimodality Index: A Criterion for Discovering and Ranking Bimodal Signatures from Cancer Gene Expression Profiling Data - 05/Aug/2009
A Generalized Beta Model for the Age Distribution of Cancers: Application to Pancreatic and Kidney Cancer - 04/Aug/2009
Joint Variable Selection and Classification with Immunohistochemical Data - 22/Jul/2009
affyPara - a Bioconductor Package for Parallelized Preprocessing Algorithms of Affymetrix Microarray Data - 22/Jul/2009
Linguistic Processing and Classification of Semi Structured Bibliographic Data on Complementary Medicine - 06/Jul/2009
Automated Detection of Conformational Epitopes Using Phage Display Peptide Sequences - 01/Jul/2009
Robust Model Selection for Classification of Microarrays - 25/Jun/2009
Angiotensin II Type 1 Receptor Blockers Reduce Urinary Angiotensinogen Excretion and the Levels of Urinary Markers of Oxidative Stress and Inflammation in Patients with Type 2 Diabetic Nephropathy - 23/Jun/2009
Graphical User Interfaces for Molecular Dynamics—Quo Vadis? - 23/Sep/2009
Gromita: A Fully Integrated Graphical User Interface to Gromacs 4 - 07/Sep/2009
Gene Expression Based Leukemia Sub‑Classification Using Committee Neural Networks - 03/Sep/2009
Unblocking Blockbusters: Using Boolean Text-Mining to Optimise Clinical Trial Design and Timeline for Novel Anticancer Drugs - 17/Aug/2009
New Advanced Technologies to Provide Decentralised and Secure Access to Medical Records: Case Studies in Oncology - 07/Aug/2009
Novel Biomarkers for the Diagnosis of Urinary Tract Infection - A Systematic Review - 05/Aug/2009
The Bimodality Index: A Criterion for Discovering and Ranking Bimodal Signatures from Cancer Gene Expression Profiling Data - 05/Aug/2009
A Generalized Beta Model for the Age Distribution of Cancers: Application to Pancreatic and Kidney Cancer - 04/Aug/2009
Joint Variable Selection and Classification with Immunohistochemical Data - 22/Jul/2009
affyPara - a Bioconductor Package for Parallelized Preprocessing Algorithms of Affymetrix Microarray Data - 22/Jul/2009
Linguistic Processing and Classification of Semi Structured Bibliographic Data on Complementary Medicine - 06/Jul/2009
Automated Detection of Conformational Epitopes Using Phage Display Peptide Sequences - 01/Jul/2009
Robust Model Selection for Classification of Microarrays - 25/Jun/2009
Angiotensin II Type 1 Receptor Blockers Reduce Urinary Angiotensinogen Excretion and the Levels of Urinary Markers of Oxidative Stress and Inflammation in Patients with Type 2 Diabetic Nephropathy - 23/Jun/2009