Home Journals Subjects About My LA Reviewers Authors News Submit
Username: Password:
.
(close)

(Ctrl-click to select multiple journals)


How should we address you?

Your email address


Enter the three character code
Visual CAPTCHA
Privacy Statement
 
 
 
 
 
 

ALFRED: An Allele Frequency Database for Microevolutionary Studies

Authors: Haseena Rajeevan, Kei-Hoi Cheung, Rohit Gadagkar, Shannon Stein, Usha Soundararajan, Judith R Kidd, Andrew J Pakstis, Perry L Miller, and Kenneth K Kidd
Publication Date: 22 Feb 2007
Evolutionary Bioinformatics Online 2005:1 1-10

Haseena Rajeevan1, Kei-Hoi Cheung1,2, Rohit Gadagkar2, Shannon Stein1, Usha Soundararajan1, Judith R Kidd1, Andrew J Pakstis1, Perry L Miller2, and Kenneth K Kidd1

1Department of Genetics, Yale University School of Medicine, New Haven, CT 06520-8005, USA. 2Center for Medical Informatics, Yale University School of Medicine, New Haven, CT 06520-8005, USA

Abstract: Many kinds of microevolutionary studies require data on multiple polymorphisms in multiple populations. Increasingly, and especially for human populations, multiple research groups collect relevant data and those data are dispersed widely in the literature. ALFRED has been designed to hold data from many sources and make them available over the web. Data are assembled from multiple sources, curated, and entered into the database. Multiple links to other resources are also established by the curators. A variety of search options are available and additional geographic based interfaces are being developed. The database can serve the human anthropologic genetic community by identifying what loci are already typed on many populations thereby helping to focus efforts on a common set of markers. The database can also serve as a model for databases handling similar DNA polymorphism data for other species.