Biomarker Insights
Synopsis: An open access, peer reviewed electronic journal that covers all aspects of biomarker research and clinical applications.
Indexing: Pubmed, Pubmed Central, EBSCO Academic Research Complete, Embase, Embiology, SCOPUS, Google Scholar, CAS, DOAJ, OAIster.
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Biomarkers in Cervical Cancer
Eun-Kyoung Yim and Jong-Sup Park
Department of Obstetrics and Gynecology, Catholic University Medical College, 505 Banpo-dong, Seocho-gu, Seoul, 137-040, Republic of Korea.
Abstract: Cervical cancer, a potentially preventable disease, remains the second most common malignancy in women worldwide. Human papillomavirus (HPV) is the single most important etiological agent in cervical cancer, contributing to neoplastic progression through the action of viral oncoproteins, mainly E6 and E7. Cervical screening programs using Pap smear testing have dramatically improved cervical cancer incidence and reduced deaths, but cervical cancer still remains a global health burden. The biomarker discovery for accurate detection and diagnosis of cervical carcinoma and its malignant precursors (collectively referred to as high-grade cervical disease) represents one of the current challenges in clinical medicine and cytopathology.
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