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Role of 99mTc-(V)DMSA in Detecting Tumor Cell Proliferation

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Publication Date: 13 Dec 2007

Journal: Analytical Chemistry Insights

Citation: Analytical Chemistry Insights 2007:2 81-83

Fatma Al-Saeedi

Department of Nuclear Medicine, Faculty of Medicine, Kuwait University, Kuwait.

Abstract:

Pentavalent technetium-99m dimercaptosuccinic acid (99mTc-(V)DMSA) is a tumor-seeking agent which was introduced to evaluate, image, and manage many types of cancers. In this review, the beginning of, and the most recent applications of using this agent was appraised. The relation with tumor cell detection and proliferation was reported and several mechanisms of uptake of 99mTc-(V)DMSA in tumor cells are described.


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