Perspectives in Medicinal Chemistry

The pKa Distribution of Drugs: Application to Drug Discovery (Published on 17 Sep 2007)

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Chaperone Therapy for Neuronopathic Lysosomal Diseases: Competitive Inhibitors as Chemical Chaperones for Enhancement of Mutant Enzyme Activities (Published on 26 May 2009)

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Lead Optimization in Discovery Drug Metabolism and Pharmacokinetics/Case study: The Hepatitis C Virus (HCV) Protease Inhibitor SCH 503034 (Published on 26 Jun 2007)

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The Role of Glucose Metabolism and Glucose-Associated Signalling in Cancer (Published on 18 Jan 2008)

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The Role of Integrins in Cancer and the Development of Anti-Integrin Therapeutic Agents for Cancer Therapy (Published on 10 Apr 2008)

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Lunasin: A Novel Cancer Preventive Seed Peptide (Published on 25 Mar 2008)

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Chemical Chaperone and Inhibitor Discovery: Potential Treatments for Protein Conformational Diseases (Published on 11 Dec 2007)

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Aminoglycosides: Molecular Insights on the Recognition of RNA and Aminoglycoside Mimics (Published on 28 Apr 2009)

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FTY720 Story. Its Discovery and the Following Accelerated Development of Sphingosine 1-Phosphate Receptor Agonists as Immunomodulators Based on Reverse Pharmacology (Published on 06 Sep 2007)

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Perspectives on Using Physcomitrella  Patens as an Alternative Production Platform for Thapsigargin and Other Terpenoid Drug Candidates (Published on 04 Mar 2009)

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Modifications of Antiepileptic Drugs for Improved Tolerability and Efficacy (Published on 14 Feb 2008)

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Exploratory Studies on Development of the Chemokine Receptor CXCR4 Antagonists Toward Downsizing (Published on 10 Feb 2008)

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Small Family with Key Contacts: Par14 and Par17 Parvulin Proteins, Relatives of Pin1, Now Emerge in Biomedical Research (Published on 07 Mar 2008)

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Bioactive and Structural Metabolites of Pseudomonas and Burkholderia Species Causal Agents of Cultivated Mushrooms Diseases (Published on 09 May 2008)

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Effects of FK506 on Ca2+ Release Channels (Review) (Published on 18 Mar 2008)

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Selected Gamma Aminobutyric Acid (GABA) Esters may Provide Analgesia for Some Central Pain Conditions (Published on 03 Aug 2010)

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Drug Targeting of α-Synuclein Oligomerization in Synucleinopathies (Published on 10 Apr 2008)

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Choroidal Proteins Involved in Cerebrospinal Fluid Production may be Potential Drug Targets for Alzheimer’s Disease Therapy (Published on 23 Feb 2011)

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Derivatives of 5-Aminolevulinic Acid for Photodynamic Therapy (Published on 11 Dec 2007)

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Stereochemical Basis for a Unified Structure Activity Theory of Aromatic and Heterocyclic Rings in Selected Opioids and Opioid Peptides (Published on 18 Feb 2010)

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Fentanyl Buccal Tablet for the Treatment of Breakthrough Pain: Pharmacokinetics of Buccal Mucosa Delivery and Clinical Efficacy (Published on 04 Jun 2010)

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Stereocomplexes Formed From Select Oligomers of Polymer d-lactic Acid (PDLA) and l-lactate May Inhibit Growth of Cancer Cells and Help Diagnose Aggressive Cancers—Applications of the Warburg Effect (Published on 15 Feb 2011)

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Revisiting the Monoamine Hypothesis of Depression: A New Perspective (Published on 03 Apr 2014)

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Low Molecular Weight Opioid Peptide Esters Could be Developed as a New Class of Analgesics (Published on 25 Jul 2011)

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Antibiotics and Bacterial Resistance in the 21st Century (Published on 28 Aug 2014)

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Pathways for Small Molecule Delivery to the Central Nervous System Across the Blood-Brain Barrier (Published on 16 Jun 2014)

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Corrigendum for “Stereocomplexes Formed From Select Oligomers of Polymer D-lactic Acid (PDLA) and L-lactate May Inhibit Growth of Cancer Cells and Help Diagnose Aggressive Cancers—Applications of the Warburg Effect” (Published on 25 May 2014)

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Multiple Sclerosis: Overview of Disease-Modifying Agents (Published on 05 Oct 2014)

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Antimicrobial Peptides and Their Analogs: Searching for New Potential Therapeutics (Published on 12 Oct 2014)

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New Approaches to Treating Alzheimer’s Disease (Published on 09 Feb 2015)

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Selective Mycobacterium tuberculosis Shikimate Kinase Inhibitors as Potential Antibacterials (Published on 15 Mar 2015)

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Applications of Second-Harmonic Generation Imaging Microscopy in Ovarian and Breast Cancer (Published on 16 Apr 2015)

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