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IMAGE: A New Tool for the Prediction of Transcription Factor Binding Sites

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Authors: R. Casilli, A. Marongiu, S. Melchionna, P. Palazzari, R. Paparcone and V. Rosato

Publication Date: 03 Oct 2008

Journal: Bioinformatics and Biology Insights

Citation: Bioinformatics and Biology Insights 2008:2 357-367

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Abstract

IMAGE is an application tool, based on the vector quantization method, aiding the discovery of nucleotidic sequences corresponding to Transcription Factor binding sites. Starting from the knowledge of regulation regions of a number of co-expressed genes, the software is able to predict the occurrence of specific motifs of different lengths (starting from 6 base pairs) with a defined number of punctual mutations.

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