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Publication Date: 12 Mar 2008
Journal: Bioinformatics and Biology Insights 2008:2 187-200
Abstract Nadine Schuurman and Agnieszka Leszczynski
Department of Geography, Simon Fraser University RCB 7123, 8888 University Drive, Burnaby, British Columbia, Canada, V5A 1S6.
Abstract
The past twenty years have witnessed an explosion of biological data in diverse database formats governed by heterogeneous infrastructures. Not only are semantics (attribute terms) different in meaning across databases, but their organization varies widely. Ontologies are a concept imported from computing science to describe different conceptual frameworks that guide the collection, organization and publication of biological data. An ontology is similar to a paradigm but has very strict implications for formatting and meaning in a computational context. The use of ontologies is a means of communicating and resolving semantic and organizational differences between biological databases in order to enhance their integration. The purpose of interoperability (or sharing between divergent storage and semantic protocols) is to allow scientists from around the world to share and communicate with each other. This paper describes the rapid accumulation of biological data, its various organizational structures, and the role that ontologies play in interoperability.
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I had an excellent experience publishing our review article in Clinical Medicine Reviews. The managing editor was very helpful and the process was very timely and transparent.Professor Jonathan A. Bernstein (University of Cincinnati College of Medicine, Division of Immunology, Allergy Section, Cincinnati, OH, USA) What our authors say
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