Publication Date: 14 Jul 2010
Type: Review
Journal: Clinical Medicine Reviews in Therapeutics
doi: 10.4137/CMRT.S1606
Fluticasone furoate is a new synthetic steroid structurally related to fluticasone propionate but with a higher affinity for the glucocorticoid receptor. It demonstrates high local efficacy and low systemic availability thus producing maximal efficacy with minimal side effects. Intranasal steroids are recommended first line treatment for allergic rhinitis in both adults and children over 2 years. The safety profile of fluticasone furoate has been evaluated in terms of its plasma concentrations, HPA axis, growth in children and bone metabolism and ocular side effects with no major side effects although further studies are warranted. The potential advantages are the new device which has been developed for delivery which is patient preferred, faster onset of action and a consistent improvement on the ocular symptoms of allergic rhinitis.
RIS citation (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)
BibTex citation (BIBDESK, LATEX)
I recommend highly Clinical Medicine Insights: Endocrinology and Diabetes as it provides guidance in each step of the publication process. The peer review was also in high quality yet very constructive.
All authors are surveyed after their articles are published. Authors are asked to rate their experience in a variety of areas, and their responses help us to monitor our performance. Presented here are their responses in some key areas. No 'poor' or 'very poor' responses were received; these are represented in the 'other' category.See Our Results
Copyright © 2013 Libertas Academica Ltd (except open access articles and accompanying metadata and supplementary files.)
FacebookGoogle+Twitter
PinterestTumblrYouTube