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Drug Target Insights

Synopsis: An open access, peer reviewed electronic journal that covers drug treatment targets.


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ISSN: 1177-3928



Aims and scope:

Drug Target Insights covers current developments in all areas of the field of clinical therapeutics. The journal has two specific areas of focus:

  • On molecular drug targets, including disease-specific proteins, receptors, enzymes, and genes.
  • The journal seeks to elucidate the impact of new therapeutic agents on patient acceptability, preference, satisfaction and quality of life.

Drug Target Insights seeks to be the most up-to-date journal for those who need to be informed of the latest and most important developments in the field. The journal seeks to be the most reliable and up-to-date journal in this field by offering rapid and credible pre-production submission processing to authors. By publishing in open-access format, authors are able to communicate with the widest possible group of readers.

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Use and Safety of Anthroposophic Medications for Acute Respiratory and Ear Infections: A Prospective Cohort Study

Authors: Harald J. Hamre, Anja Glockmann, Michael Fischer, David S. Riley, Erik Baars and Helmut Kiene
Publication Date: 17 Sep 2007
Drug Target Insights 2007:2 209-219

Harald J. Hamre1, Anja Glockmann1, Michael Fischer2, David S. Riley3, Erik Baars4 and Helmut Kiene1

1Institute for Applied Epistemology and Medical Methodology, Freiburg, Germany. 2ClinResearch GmbH, Cologne, Germany. 3University of New Mexico School of Medicine, Santa Fe, New Mexico, U.S.A. 4Louis Bolk Instituut, Driebergen, The Netherlands.

Abstract

Objective: Anthroposophic medications (AMED) are widely used, but safety data on AMED from large prospective studies are sparse. The objective of this analysis was to determine the frequency of adverse drug reactions (ADR) to AMED in outpatients using AMED for acute respiratory and ear infections.

Methods: A prospective four-week observational cohort study was conducted in 21 primary care practices in Europe and the U.S.A. The cohort comprised 715 consecutive outpatients aged 1 month, treated by anthroposophic physicians for acute otitis and respiratory infections. Physicians’ prescription data and patient reports of adverse events were analyzed. Main outcome measures were use of AMED and ADR to AMED.

Results: Two patients had confirmed ADR to AMED: 1) swelling and redness at the injection site after subcutaneous injections of Prunus spinosa 5%, 2) sleeplessness after intake of Pneumodoron® 2 liquid. These ADR lasted one and two days respectively; both subsided after dose reduction; none were unexpected; none were serious. The frequency of confirmed ADR to AMED was 0.61% (2/327) of all different AMED used, 0.28% (2/715) of patients, and 0.004% (3/73,443) of applications.

Conclusion: In this prospective study, anthroposophic medications used by primary care patients with acute respiratory or ear infections were well tolerated.

Abbreviations: A-: anthroposophy; ADR: adverse drug reactions; AE: adverse events; AM: anthroposophic medicine; AMED: AM medication; C-: conventional; ENE-patients: eligible, not enrolled patients; IIPCOS: International Primary Care Outcomes Study

Categories: Pharmacology


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Posted by
07:49,January 07, 2008

I am positively shocked that a serious journal publishes this. Anthroposophic "medicine" is complete and utter humbug and no serious researcher should be concerned with it. That the general public uses it is no excuse to spend time on that medieval rubbish. Common sense alone will tell us that 1. Anthroposophic drugs will not work and will therefore 2. Be safe with minimal adverse reactions. Open journals, fine, but not so open that our minds fall out please. M van Steensel, MD PhD


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