Home| About us| My LA: login/register| For authors| For reviewers| Submit a paper
(close)

(Ctrl-click to select multiple journals)


How should we address you?

Your email address


 Yes, sign up now
 Sign up for general news too

Privacy Statement
 
 
 

Clinical Medicine: Pathology

Synopsis: An open access, peer reviewed electronic journal that covers histopathology, haematology, biochemistry, virology, parasitology, infection control and medical microbiology.


Indexing: 5 major databases. Pubmed indexing for NIH-funded research.

Processing time: Decision in 2 weeks for 90% of papers.

Visibility: Most popular article read 800+ times.

View factor
for journal
32239


About this journal

Aims and scope:

Clinical Medicine: Pathology is an international, open access, peer reviewed journal which considers manuscripts on histopathology, haematology, biochemistry, virology, parasitology, infection control and medical microbiology.

Editorial standards and procedures:

Submissions, excluding editorials, letters to the editor and dedications, will be peer reviewed by two reviewers.  Reviewers are required to provide fair, balanced and constructive reports.  

Under our Fairness in Peer Review Policy authors may appeal against reviewers' recommendations which are ill-founded, unobjective or unfair.  Appeals are considered by the Editor in Chief or Associate Editor.

Papers are not sent to peer reviewers following submission of a revised manuscript. Editorial decisions on re-submitted papers are based on the author's response to the initial peer review report.

Indexing:

This journal is indexed by the following services:

  • Google Scholar
  • CAS
  • DOAJ
  • SCOPUS
  • Embase

SPARC Europe Seal award winner:

This journal has been awarded a SPARC Europe Seal. The Seal is an initiative of SPARC Europe (Scholarly Publishing and Academic Resources Coalition) and the Directory of Open Access Journals (DOAJ) which is awarded to journals applying a Creative Commons CC-BY copyright license and that make journal metadata accessible to DOAJ.  

Amongst other important services DOAJ makes metadata OAI-compliant.  This in turn enhances the visibility of papers and allows OAI-harvesters to include the details of journal articles in their services. We encourage readers to make use of this valuable resource.  The DOAJ search page is available here.

National Institutes of Health Public Access Policy compliant:

As of April 7 2008, the US NIH Public Access Policy requires that all peer reviewed articles resulting from research carried out with NIH funding be deposited in the Pubmed Central archive.

If you are an NIH employee or grantee Libertas Academica will ensure that you comply with the policy by depositing your paper at Pubmed Central on your behalf. 

ISSN: 1178-1181


Bookmark journal

FACEBOOK
YAHOO! BUZZ
DIGG
LINKEDIN
Add to Mixx! MIXX
PERMALINK


 
 
 


The Pathogenesis of Autism

Authors: Timothy John Watts
Publication Date: 18 Sep 2008
Clinical Medicine: Pathology 2008:1 99-103

Timothy John Watts

Barts and the London School of Medicine and Dentistry, Turner Street, London, E1 2AD, U.K.

Abstract

Autism is well known as a complex developmental disorder with a seemingly confusing and uncertain pathogenesis. The definitive mechanisms that promote autism are poorly understood and mostly unknown, yet available theories do appear to focus on the disruption of normal cerebral development and its subsequent implications on the functional brain unit. This mini-review aims solely to discuss and evaluate the most prominent current theories regarding the pathogenesis of autism. The main conclusion is that although there is not a clear pathway of mechanisms directed towards a simple pathogenesis and an established link to autism on the symptomatic level; there are however several important theories (neural connectivity, neural migration, excitatory-inhibitory neural activity, dendritic morphology, neuroimmune; calcium signalling and mirror neurone) which appear to offer an explanation to how autism develops. It seems probable that autism’s neurodevelopmental defect is ‘multi-domain’ in origin (rather than a single anomaly) and is hence distributed across numerous levels of study (genetic, immunopathogenic, etc.). A more definitive understanding of the pathogenesis could facilitate the development of better treatments for this complex psychiatric disorder.

Categories: Pathology


Post comment




No comments yet...Be the first to comment.

Document tools

Download PDF
(182.34 KB)
Request Reprints

Bookmark this article

LINKEDIN FACEBOOK

Add to Mixx! MIXX YAHOO! BUZZ

PERMALINK DIGG


Sign up for free journal updates

How should we address you?
Your email address
 Yes, sign up now


Recently published in this journal

Treated Choroidal Melanoma with Late Metastases to the Contralateral Orbit
- 03/Apr/2009

Pharmacotherapeutic Options for Visceral Leishmaniasis - Current Scenario
- 23/Jan/2009

Pneumococcal Induced T-activation with Resultant Thrombotic Microangiopathy. A case report and overview (Provisional PDF)
- 08/Jan/2009

Pathology-Dependent Histological Changes of the Left Stellate Ganglia: A Cadaveric Study
- 30/Oct/2008

The Pathogenesis of Autism
- 18/Sep/2008

Histopathologic Review of Previously Negative Prostatic Core Needle Biopsies Following a New Diagnosis of Adenocarcinoma of the Prostate by Core Needle Biopsies: Implications for Quality Assurance Programs
- 16/Sep/2008

Progesterone and Estrogen Receptors in Neurofibromas of Patients with NF1
- 15/Sep/2008

Commonality Between Diabetes and Alzheimer’s Disease and A New Strategy for the Therapy
- 28/Jul/2008

Mutation Detection in the Menkes Gene AT P 7A Using the Protein Truncation Test
- 19/Jun/2008

Histological Changes on Liver Glycogen Storage in Mice (Mus musculus) Caused by Unbalanced Diets
- 23/Apr/2008

Combined Hepatocellular Cholangiocarcinomas; Analysis of a Large Database
- 19/Mar/2008

P16/Ki-67 Immunostaining is Useful in Stratification of Atypical Metaplastic Epithelium of the Cervix
- 19/Mar/2008

Combination of Immunohistochemistry and Ploidy Analysis to Assist Histopathological Diagnosis of Molar Diseases
- 19/Mar/2008

Sclerosing ‘Mucinous’ Blue Nevus: A Clinical Simulator of Dermatofibroma
- 19/Mar/2008

Squamous Differentiation and Cytokeratin Expression in an Osteosarcoma: A Case Report and Review of the Literature
- 18/Mar/2008

Tumorigenic Effects of Tamoxifen on the Female Genital Tract
- 01/Mar/2008

P16 and Ki67 Immunostains Decrease Intra- and Interobserver Variability in the Diagnosis and Grading of Anal Intraepithelial Neoplasia (AIN)
- 09/Feb/2008

First-ever Ischemic Stroke after a Flight in a Patient with Prior Poliomyelitis
- 01/Feb/2008



Related journals...