Clinical Medicine: Case Reports
Synopsis: An open access, peer reviewed electronic journal that covers case reports in all areas of clinical medicine.
Indexing: 4 major databases. Pubmed indexing for NIH-funded research.
Processing time: Decision in 2 weeks for 90% of papers.
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Journal: 72899
Most read article: 2037
Editor in chief:
Karna Dev Bardhan
ISSN: 1178-6450
Pathological Rupture of the Spleen in Uncomplicated Myeloma
Authors: Vincent Ho, Andrew Shearer and Mark Jagusch
Publication Date: 22 Apr 2008
Clinical Medicine: Case Reports 2008:1 19-23
Vincent Ho1, Andrew Shearer2 and Mark Jagusch3
1Clinical Senior Lecturer, School of Medicine, James Cook University, Cairns, Queensland, Australia. 2Haematologist, Department of Medicine, Cairns Base Hospital, Cairns, Queensland, Australia. 3Head Department of Pathology, Cairns Base Hospital, Cairns, Queensland, Australia.
Abstract
Pathological rupture of the spleen in uncomplicated myeloma is extremely rare. We present a case of a splenic rupture which occurred in a 52 year old woman with uncomplicated multiple myeloma. The patient required an urgent splenectomy and had an uneventful recovery. Pathophysiological mechanisms leading to splenic rupture are discussed. Plasma cell leukaemias have been previously documented to present with splenic rupture. A subgroup of aggressive multiple myelomas such as in our case may have a similar tendency for splenic rupture.
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