International Journal of Tryptophan Research

2015:8

Enantiomeric Separation of Monosubstituted Tryptophan Derivatives and Metabolites by HPLC with a Cinchona Alkaloid-Based Zwitterionic Chiral Stationary Phase and Its Application to the Evaluation of the Optical Purity of Synthesized 6-Chloro-L-Tryptophan
Takeshi Fukushima, Anna Sugiura, Ippei Furuta, Sumiko Iwasa, Hideaki Iizuka, Hideaki Ichiba, Mayu Onozato, Hidemasa Hikawa and Yuusaku Yokoyama
International Journal of Tryptophan Research 2015:8 1-5
Original research | Published on 07 Jan 2015

The Aryl Hydrocarbon Receptor: A Review of Its Role in the Physiology and Pathology of the Integument and Its Relationship to the Tryptophan Metabolism
Rowland Noakes
International Journal of Tryptophan Research 2015:8 7-18
Original research | Published on 10 Feb 2015

Conversion Percentage of Tryptophan to Nicotinamide is Higher in Rice Protein Diet than in Wheat Protein Diet in Rats
Katsumi Shibata, Tsutomu Fukuwatari and Tomoyo Kawamura
International Journal of Tryptophan Research 2015:8 19-25
Original research | Published on 05 Mar 2015

Tryptophan-Ethylester, the False (Unveiled) Melatonin Isomer in Red Wine
Marcello Iriti and Ileana Vigentini
International Journal of Tryptophan Research 2015:8 27-29
Original research | Published on 30 Mar 2015

Method for Evaluation of the Requirements of B-group Vitamins Using Tryptophan Metabolites in Human Urine
Katsumi Shibata, Junko Hirose and Tsutomu Fukuwatari
International Journal of Tryptophan Research 2015:8 31-39
Original research | Published on 19 Apr 2015

Tryptophan Catabolism in Chronic Viral Infections: Handling Uninvited Guests
Vikram Mehraj and Jean-Pierre Routy
International Journal of Tryptophan Research 2015:8 41-48
Original research | Published on 04 Aug 2015

Chronic Antipsychotic Treatment in the Rat – Effects on Brain Interleukin-8 and Kynurenic Acid
Markus K. Larsson, Lilly Schwieler, Michel Goiny, Sophie Erhardt and Göran Engberg
International Journal of Tryptophan Research 2015:8 49-52
Original research | Published on 20 Sep 2015

2014:7

Kynurenic Acid Levels in Cerebrospinal Fluid from Patients with Alzheimer's Disease or Dementia with Lewy Bodies
Malin Wennström, Henrietta M Nielsen, Funda Orhan, Elisabet Londos, Lennart Minthon and Sophie Erhardt
International Journal of Tryptophan Research 2014:7 1-7
Original research | Published on 28 Apr 2014

Tryptophan and Kynurenic Acid May Produce an Amplified Effect in Central Fatigue Induced by Chronic Sleep Disorder
Masatoshi Yamashita and Takanobu Yamamoto
International Journal of Tryptophan Research 2014:7 9-14
Original research | Published on 14 May 2014

Imbalanced Kynurenine Pathway in Schizophrenia
Magdalena E. Kegel, Maria Bhat, Elisabeth Skogh, Martin Samuelsson, Kristina Lundberg, Marja-Liisa Dahl, Carl Sellgren, Lilly Schwieler, Göran Engberg, Ina Schuppe-Koistinen, and Sophie Erhardt
International Journal of Tryptophan Research 2014:7 15-22
Original research | Published on 16 Sep 2014

Mechanisms of the Pellagragenic Effect of Leucine: Stimulation of Hepatic Tryptophan Oxidation by Administration of Branched-Chain Amino Acids to Healthy Human Volunteers and the Role of Plasma Free Tryptophan and Total Kynurenines
Abdulla A-B Badawy, Sarah L. Lake and Donald M. Dougherty
International Journal of Tryptophan Research 2014:7 23-32
Original research | Published on 04 Dec 2014

2013:Suppl. 1 ISTRY 2013

ISTRY 2013 Special Issue
Gilles J. Guillemin
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 1-2
Original research | Published on 21 Jul 2013

Nutritional Aspect of Tryptophan Metabolism
Tsutomu Fukuwatari and Katsumi Shibata
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 3-8
Original research | Published on 21 Jul 2013

Determination of L-tryptophan and L-kynurenine in Human Serum by using LC-MS after Derivatization with (R)-DBD-PyNCS
Hayato Ohashi, Hideaki Iizuka, Shunsuke Yoshihara, Hayato Otani, Misato Kume, Kiyomi Sadamoto, Hideaki Ichiba and Takeshi Fukushima
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 9-14
Original research | Published on 21 Jul 2013

Role of NAD+, Oxidative Stress, and Tryptophan Metabolism in Autism Spectrum Disorders
Musthafa Mohamed Essa, Selvaraju Subash, Nady Braidy, Samir Al-Adawi, Chai K Lim, Tamilarasan Manivasagam and Gilles J Guillemin
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 15-28
Original research | Published on 21 Jul 2013

Induction of TDO2 and IDO2 in Liver by High-Fat Feeding in Mice: Discrepancies with Human Obesity
Odile Poulain-Godefroy, Elodie Eury, Audrey Leloire, Benjamin Hennart, Gilles J. Guillemin, Delphine Allorge, and Philippe Froguel
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 29-37
Original research | Published on 21 Jul 2013

Kynurenine Pathway Pathologies: do Nicotinamide and Other Pathway Co-Factors have a Therapeutic Role in Reduction of Symptom Severity, Including Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM)
Adele Blankfield
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 39-45
Original research | Published on 21 Jul 2013

Species and Cell Types Difference in Tryptophan Metabolism
Yuki Murakami and Kuniaki Saito
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 47-54
Original research | Published on 21 Jul 2013

Tryptophan-Restriction Diets Help to Maintain L-Tryptophan Homeostasis in Tryptophan 2,3-Dioxygenase Knockout Mice
Akihiro Maeta, Tsutomu Fukuwatari, Hiroshi Funakoshi, Toshikazu Nakamura and Katsumi Shibata
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 55-65
Original research | Published on 21 Jul 2013

Exploitation of the IDO Pathway in the Therapy of Rheumatoid Arthritis
Richard O. Williams
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 67-73
Original research | Published on 21 Jul 2013

Relationships between Salivary Melatonin Levels, Quality of Sleep, and Stress in Young Japanese Females
Yasuhiro Ito, Tadayuki Iida, Yuumi Yamamura, Mayu Teramura, Yasushi Nakagami, Kaoru Kawai, Yoichi Nagamura and Ryoji Teradaira
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 75-85
Original research | Published on 10 Oct 2013

2013:6

Transport of Kynurenic Acid by Rat Organic Anion Transporters rOAT1 and rOAT3: Species Difference between Human and Rat in OAT1
Yuichi Uwai, Hiroaki Hara and Kikuo Iwamoto
International Journal of Tryptophan Research 2013:6 1-6
Original research | Published on 17 Feb 2013

Characterization of the Kynurenine Pathway and Quinolinic Acid Production in Macaque Macrophages
Chai K. Lim, Margaret M.C. Yap, Stephen J. Kent, Gabriel Gras, Boubekeur Samah, Jane C. Batten, Robert De Rose, Benjamin Heng, Bruce J. Brew, and Gilles J. Guillemin
International Journal of Tryptophan Research 2013:6 7-19
Original research | Published on 15 May 2013

L-Tryptophan Metabolism in Pregnant Mice Fed a High L-Tryptophan Diet and the Effect on Maternal, Placental, and Fetal Growth
Ai Tsuji, Chifumi Nakata, Mitsue Sano, Tsutomu Fukuwatari and Katsumi Shibata
International Journal of Tryptophan Research 2013:6 21-33
Original research | Published on 14 Aug 2013

The Tumor-Selective Cytotoxic Agent ß-Lapachone is a Potent Inhibitor of IDO1
Hollie E. Flick, Judith M. LaLonde, William P. Malachowski and Alexander J. Muller
International Journal of Tryptophan Research 2013:6 35-45
Original research | Published on 19 Aug 2013

Kynurenic Acid in the Digestive System—New Facts, New Challenges
Michal P. Turski, Monika Turska, Piotr Paluszkiewicz, Jolanta Parada-Turska and Gregory F. Oxenkrug
International Journal of Tryptophan Research 2013:6 47-55
Original research | Published on 04 Sep 2013

The Kynurenine Pathway in Stem Cell Biology
Simon P. Jones, Gilles J. Guillemin and Bruce J. Brew
International Journal of Tryptophan Research 2013:6 57-66
Original research | Published on 15 Sep 2013

Effects of Tranilast on the Urinary Excretion of Kynurenic and Quinolinic Acid Under Conditions of L Tryptophan Loading
Rowland R. Noakes
International Journal of Tryptophan Research 2013:6 67-71
Original research | Published on 22 Sep 2013

Big Brains, Meat, Tuberculosis, and the Nicotinamide Switches: Co-Evolutionary Relationships with Modern Repercussions?
Adrian C. Williams and Robin I.M. Dunbar
International Journal of Tryptophan Research 2013:6 73-88
Original research | Published on 15 Oct 2013

Sustained Elevation of Kynurenic Acid in the Cerebrospinal Fluid of Patients with Herpes Simplex Virus Type 1 Encephalitis
Ann Atlas, Elisabeth Franzen-Röhl, Johan Söderlund, Erik G Jönsson, Martin Samuelsson, Lilly Schwieler, Birgit Sköldenberg and Göran Engberg
International Journal of Tryptophan Research 2013:6 89-96
Original research | Published on 25 Nov 2013

Immunohistochemical Studies of the Kynurenine Pathway in Morphea
Rowland Noakes, Nick Mellick
International Journal of Tryptophan Research 2013:6 97-102
Original research | Published on 23 Dec 2013

2012:5

Quinolinic Acid, an Endogenous Molecule Combining Excitotoxicity, Oxidative Stress and Other Toxic Mechanisms
Verónica Pérez-De La Cruz, Paul Carrillo-Mora and Abel Santamaría
International Journal of Tryptophan Research 2012:5 1-8
Original research | Published on 23 Feb 2012

A Jerte Valley Cherry-Based Product as a Supply of Tryptophan
María Garrido, Javier Espino, Antonio F. Toribio-Delgado, Javier Cubero, Juan I. Maynar-Mariño, Carmen Barriga, Sergio D. Paredes and Ana B. Rodríguez
International Journal of Tryptophan Research 2012:5 9-14
Original research | Published on 16 Apr 2012

Kynurenine Pathway in Skin Cells: Implications for UV-Induced Skin Damage
Diba Sheipouri, Nady Braidy, and Gilles J. Guillemin,
International Journal of Tryptophan Research 2012:5 15-25
Original research | Published on 03 Jul 2012

A Brief Historic Overview of Clinical Disorders Associated with Tryptophan: The Relevance to Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM)
Adele Blankfield
International Journal of Tryptophan Research 2012:5 27-32
Original research | Published on 17 Sep 2012

Fate of Dietary Tryptophan in Young Japanese Women
Chiaki Hiratsuka, Tsutomu Fukuwatari and Katsumi Shibata
International Journal of Tryptophan Research 2012:5 33-47
Original research | Published on 30 Oct 2012

Kynurenic Acid Metabolism in Various Types of Brain Pathology in HIV-1 Infected Patients
H. Baran, J.A. Hainfellner and B. Kepplinger
International Journal of Tryptophan Research 2012:5 49-64
Original research | Published on 13 Dec 2012

2011:4

Tryptophan Oxidative Metabolism Catalyzed by Geobacillus Stearothermophilus: A Thermophile Isolated from Kuwait Soil Contaminated with Petroleum Hydrocarbons
Jassim M. Al-Hassan, Samira Al-Awadi, Sosamma Oommen, Abdulaziz Alkhamis and Mohammad Afzal
International Journal of Tryptophan Research 2011:4 1-6
Original research | Published on 10 Jan 2011

Modulation of Tryptophan Metabolism, Promotion of Neurogenesis and Alteration of Anxiety-Related Behavior in Tryptophan 2,3-Dioxygenase-Deficient Mice
Hiroshi Funakoshi, Masaaki Kanai, and Toshikazu Nakamura
International Journal of Tryptophan Research 2011:4 7-18
Original research | Published on 11 Apr 2011

Tryptophan Transport in Human Fibroblast Cells— A Functional Characterization
Vumma Ravi, Johansson Jessica, Lewander Tommy and Venizelos Nikolaos
International Journal of Tryptophan Research 2011:4 19-27
Original research | Published on 19 Apr 2011

Effects of Kynurenine Pathway Inhibition on NAD+ Metabolism and Cell Viability in Human Primary Astrocytes and Neurons
Nady Braidy, Gilles J. Guillemin and Ross Grant
International Journal of Tryptophan Research 2011:4 29-37
Original research | Published on 08 May 2011

L-Tryptophan Production by Auxotrophic and Analogue Resistant Mutants of Aureobacterium flavescens
A. Roy and S.K. Mukhopadhyay
International Journal of Tryptophan Research 2011:4 39-46
Original research | Published on 29 May 2011

Kynurenine Pathway Hypothesis: The Nature of the Chronic Fatigue Syndrome (CFS) Revisited
Adele Blankfield
International Journal of Tryptophan Research 2011:4 47-48
Original research | Published on 31 Jul 2011

Stochastic Resonance Activity Influences Serum Tryptophan Metabolism in Healthy Human Subjects
Berthold Kepplinger, Halina Baran, Brenda Sedlnitzky-Semler, Nagy-Roland Badawi and Helene Erhart
International Journal of Tryptophan Research 2011:4 49-60
Original research | Published on 08 Nov 2011

2010:3

Role of the NMDA-receptor in Prepulse Inhibition in the Rat
Klas Linderholm, Susan Powell, Elin Olsson, Maria Holtze, Ralph Snodgrass and Sophie Erhardt
International Journal of Tryptophan Research 2010:3 1-12
Original research | Published on 12 Feb 2010

Endogenous Kynurenine Aminotransferases Inhibitor is Proposed to Act as “Glia Depressing Factor” (GDF)
Halina Baran, Berthold Kepplinger and Markus Draxler
International Journal of Tryptophan Research 2010:3 13-22
Original research | Published on 11 May 2010

Specificity of the Acute Tryptophan and Tyrosine Plus Phenylalanine Depletion and Loading Tests I. Review of Biochemical Aspects and Poor Specificity of Current Amino Acid Formulations
Abdulla A.-B. Badawy, Donald M. Dougherty and Dawn M. Richard
International Journal of Tryptophan Research 2010:3 23-34
Original research | Published on 02 Jun 2010

Specificity of the Acute Tryptophan and Tyrosine Plus Phenylalanine Depletion and Loading Tests Part II: Normalisation of the Tryptophan and the Tyrosine Plus Phenylalanine to Competing Amino Acid Ratios in a New Control Formulation
Abdulla A.-B. Badawy, Donald M. Dougherty and Dawn M. Richard
International Journal of Tryptophan Research 2010:3 35-47
Original research | Published on 09 Jun 2010

Editorial ISTRY Special Issue
Gilles J. Guillemin
International Journal of Tryptophan Research 2010:3 49-50
Original research | Published on 10 Jun 2010

On the Biological Importance of the 3-hydroxyanthranilic Acid: Anthranilic Acid Ratio
L. Gail Darlington, Caroline M. Forrest, Gillian M. Mackay, Robert A. Smith, Andrew J. Smith, Nicholas Stoy and Trevor W. Stone
International Journal of Tryptophan Research 2010:3 51-59
Original research | Published on 10 Jun 2010

Accelerated Tryptophan Degradation Predicts Poor Survival in Trauma and Sepsis Patients
Martin Ploder, Andreas Spittler, Katharina Kurz, Gabriele Neurauter, Linda E. Pelinka, Erich Roth and Dietmar Fuchs
International Journal of Tryptophan Research 2010:3 61-67
Original research | Published on 10 Jun 2010

Serum Levels of Tryptophan, 5-Hydroxytryptophan and Serotonin in Patients Affected with Different Forms of Amenorrhea
S. Comai, A. Bertazzo, N. Carretti, A. Podfigurna-Stopa, S. Luisi and C.V.L. Costa
International Journal of Tryptophan Research 2010:3 69-75
Original research | Published on 10 Jun 2010

Indoleamine 2,3-Dioxygenase in Human Hematopoietic Stem Cell Transplantation
Birgit Jürgens, Julia Raberger, Dietmar Fuchs and Andreas Heitger
International Journal of Tryptophan Research 2010:3 77-90
Original research | Published on 10 Jun 2010

Proteasomal Degradation of Indoleamine 2,3-Dioxygenase  in CD8+ Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3)
Maria T. Pallotta, Ciriana Orabona, Claudia Volpi, Ursula Grohmann, Paolo Puccetti and Francesca Fallarino
International Journal of Tryptophan Research 2010:3 91-97
Original research | Published on 10 Jun 2010

Effects of Acute Tryptophan Depletion on Three Different Types of Behavioral Impulsivity
Donald M. Dougherty, Dawn M. Richard, Lisa M. James and Charles W. Mathias
International Journal of Tryptophan Research 2010:3 99-111
Original research | Published on 10 Jun 2010

IDO-Mediated Tryptophan Degradation in the Pathogenesis of Malignant Tumor Disease
Robert Sucher, Katharina Kurz, Guenter Weiss, Raimund Margreiter, Dietmar Fuchs and Gerald Brandacher
International Journal of Tryptophan Research 2010:3 113-120
Original research | Published on 10 Jun 2010

Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder
Nicholas W.S. Davies, Gilles Guillemin and Bruce J. Brew
International Journal of Tryptophan Research 2010:3 121-140
Original research | Published on 10 Jun 2010

Implication of Tryptophan 2,3-Dioxygenase and its Novel Variants in the Hippocampus and Cerebellum During the Developing and Adult Brain
Masaaki Kanai, Hiroshi Funakoshi and Toshikazu Nakamura
International Journal of Tryptophan Research 2010:3 141-149
Original research | Published on 23 Jul 2010

Kynurenine Pathway Metabolism is Involved in the Maintenance of the Intracellular NAD+ Concentration in Human Primary Astrocytes
Ross Grant, Susan Nguyen and Gilles Guillemin
International Journal of Tryptophan Research 2010:3 151-156

Original research | Published on 03 Aug 2010

Understanding the Roles of the Kynurenine Pathway in Multiple Sclerosis Progression
Chai K. Lim, Bruce J. Brew, Gayathri Sundaram and Gilles J. Guillemin
International Journal of Tryptophan Research 2010:3 157-167
Original research | Published on 25 Aug 2010

Alzheimer’s and Seizures: Interleukin-18, Indoleamine 2,3-Dioxygenase and Quinolinic Acid
Anderson G and Ojala JO
International Journal of Tryptophan Research 2010:3 169-173
Original research | Published on 15 Oct 2010

Rapid Isocratic Liquid Chromatographic Separation and Quantification of Tryptophan and Six kynurenine Metabolites in Biological Samples with Ultraviolet and Fluorimetric Detection
Abdulla A-B Badawy and Christopher J Morgan
International Journal of Tryptophan Research 2010:3 175-186
Original research | Published on 08 Dec 2010

2009:2

Kynurenine Pathway Metabolites in Humans: Disease and Healthy States
Yiquan Chen and Gilles J. Guillemin
International Journal of Tryptophan Research 2009:2 1-19
Original research | Published on 08 Jan 2009 | Highly accessed (previous month)

Dedication: Paolo Guidetti
Robert Schwarcz
International Journal of Tryptophan Research 2009:2 21-22
Original research | Published on 16 Feb 2009

Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model
Sergio D. Paredes, Carmen Barriga, Russel J. Reiter and Ana B. Rodríguez
International Journal of Tryptophan Research 2009:2 23-36
Original research | Published on 14 Jan 2009

Production and Peripheral Roles of 5-HTP, a Precursor of Serotonin
Kazuhiro Nakamura and Hiroyuki Hasegawa
International Journal of Tryptophan Research 2009:2 37-43
Original research | Published on 30 Mar 2009

L -Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications
Dawn M Richard, Michael A Dawes, Charles W Mathias, Ashley Acheson, Nathalie Hill-Kapturczak and Donald M Dougherty
International Journal of Trytophan Research 2009:2 45-60
Original research | Published on 23 Mar 2009

Effects of Kynurenine Pathway Metabolites on Intracellular NAD+ Synthesis and Cell Death in Human Primary Astrocytes and Neurons

Nady Braidy, Ross Grant, Bruce J Brew, Seray Adams, Tharusha Jayasena and Gilles J. Guillemin

International Journal of Tryptophan Research 2009:2 61-69

Original research | Published on 03 Apr 2009

The Physiological Action of Picolinic Acid in the Human Brain
R.S. Grant, S.E. Coggan and G.A. Smythe
International Journal of Tryptophan Research 2009:2 71-79
Original research | Published on 28 Apr 2009

2008:1

Introductory Editorial (International Journal of Tryptophan Research)
Gilles J. Guillemin
International Journal of Tryptophan Research 2008:1 1
Original research | Published on 09 Apr 2008

Tryptophan Research in Panic Disorder
Eduard Maron, Jakov Shlik and David J. Nutt
International Journal of Tryptophan Research 2008:1 3-12
Original research | Published on 14 Aug 2008