International Journal of Tryptophan Research

Effects of Tranilast on the Urinary Excretion of Kynurenic and Quinolinic Acid Under Conditions of L Tryptophan Loading
Rowland R. Noakes
International Journal of Tryptophan Research 2013:6 67-71
Original Research | Published on 22 Sep 2013

Kynurenine Pathway Metabolites in Humans: Disease and Healthy States
Yiquan Chen and Gilles J. Guillemin
International Journal of Tryptophan Research 2009:2 1-19
Published on 08 Jan 2009 | Highly accessed (previous month)

L -Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications
Dawn M Richard, Michael A Dawes, Charles W Mathias, Ashley Acheson, Nathalie Hill-Kapturczak and Donald M Dougherty
International Journal of Trytophan Research 2009:2 45-60
Published on 23 Mar 2009

The Physiological Action of Picolinic Acid in the Human Brain
R.S. Grant, S.E. Coggan and G.A. Smythe
International Journal of Tryptophan Research 2009:2 71-79
Review | Published on 28 Apr 2009

Effects of Kynurenine Pathway Metabolites on Intracellular NAD+ Synthesis and Cell Death in Human Primary Astrocytes and Neurons

Nady Braidy, Ross Grant, Bruce J Brew, Seray Adams, Tharusha Jayasena and Gilles J. Guillemin

International Journal of Tryptophan Research 2009:2 61-69

Published on 03 Apr 2009

Tryptophan Research in Panic Disorder
Eduard Maron, Jakov Shlik and David J. Nutt
International Journal of Tryptophan Research 2008:1 3-12
Published on 14 Aug 2008

Tryptophan-Restriction Diets Help to Maintain L-Tryptophan Homeostasis in Tryptophan 2,3-Dioxygenase Knockout Mice
Akihiro Maeta, Tsutomu Fukuwatari, Hiroshi Funakoshi, Toshikazu Nakamura and Katsumi Shibata
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 55-65
Original Research | Published on 21 Jul 2013

Effects of Kynurenine Pathway Inhibition on NAD+ Metabolism and Cell Viability in Human Primary Astrocytes and Neurons
Nady Braidy, Gilles J. Guillemin and Ross Grant
International Journal of Tryptophan Research 2011:4 29-37
Original Research | Published on 08 May 2011

Assessment of the Potential Role of Tryptophan as the Precursor of Serotonin and Melatonin for the Aged Sleep-wake Cycle and Immune Function: Streptopelia Risoria as a Model
Sergio D. Paredes, Carmen Barriga, Russel J. Reiter and Ana B. Rodríguez
International Journal of Tryptophan Research 2009:2 23-36
Published on 14 Jan 2009

Production and Peripheral Roles of 5-HTP, a Precursor of Serotonin
Kazuhiro Nakamura and Hiroyuki Hasegawa
International Journal of Tryptophan Research 2009:2 37-43
Published on 30 Mar 2009

Serum Levels of Tryptophan, 5-Hydroxytryptophan and Serotonin in Patients Affected with Different Forms of Amenorrhea
S. Comai, A. Bertazzo, N. Carretti, A. Podfigurna-Stopa, S. Luisi and C.V.L. Costa
International Journal of Tryptophan Research 2010:3 69-75
Original Research - Special Issue | Published on 10 Jun 2010

Introductory Editorial (International Journal of Tryptophan Research)
Gilles J. Guillemin
International Journal of Tryptophan Research 2008:1 1
Published on 09 Apr 2008

Understanding the Roles of the Kynurenine Pathway in Multiple Sclerosis Progression
Chai K. Lim, Bruce J. Brew, Gayathri Sundaram and Gilles J. Guillemin
International Journal of Tryptophan Research 2010:3 157-167
Review | Published on 25 Aug 2010

Effects of Acute Tryptophan Depletion on Three Different Types of Behavioral Impulsivity
Donald M. Dougherty, Dawn M. Richard, Lisa M. James and Charles W. Mathias
International Journal of Tryptophan Research 2010:3 99-111
Original Research - Special Issue | Published on 10 Jun 2010

On the Biological Importance of the 3-hydroxyanthranilic Acid: Anthranilic Acid Ratio
L. Gail Darlington, Caroline M. Forrest, Gillian M. Mackay, Robert A. Smith, Andrew J. Smith, Nicholas Stoy and Trevor W. Stone
International Journal of Tryptophan Research 2010:3 51-59
Hypothesis - Special Issue | Published on 10 Jun 2010

Kynurenine Pathway Metabolism is Involved in the Maintenance of the Intracellular NAD+ Concentration in Human Primary Astrocytes
Ross Grant, Susan Nguyen and Gilles Guillemin
International Journal of Tryptophan Research 2010:3 151-156

Short Report | Published on 03 Aug 2010

Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder
Nicholas W.S. Davies, Gilles Guillemin and Bruce J. Brew
International Journal of Tryptophan Research 2010:3 121-140
Review - Special Issue | Published on 10 Jun 2010

Tryptophan Transport in Human Fibroblast Cells— A Functional Characterization
Vumma Ravi, Johansson Jessica, Lewander Tommy and Venizelos Nikolaos
International Journal of Tryptophan Research 2011:4 19-27
Original Research | Published on 19 Apr 2011

Tryptophan Oxidative Metabolism Catalyzed by Geobacillus Stearothermophilus: A Thermophile Isolated from Kuwait Soil Contaminated with Petroleum Hydrocarbons
Jassim M. Al-Hassan, Samira Al-Awadi, Sosamma Oommen, Abdulaziz Alkhamis and Mohammad Afzal
International Journal of Tryptophan Research 2011:4 1-6
Original Research | Published on 10 Jan 2011

IDO-Mediated Tryptophan Degradation in the Pathogenesis of Malignant Tumor Disease
Robert Sucher, Katharina Kurz, Guenter Weiss, Raimund Margreiter, Dietmar Fuchs and Gerald Brandacher
International Journal of Tryptophan Research 2010:3 113-120
Review - Special Issue | Published on 10 Jun 2010

Modulation of Tryptophan Metabolism, Promotion of Neurogenesis and Alteration of Anxiety-Related Behavior in Tryptophan 2,3-Dioxygenase-Deficient Mice
Hiroshi Funakoshi, Masaaki Kanai, and Toshikazu Nakamura
International Journal of Tryptophan Research 2011:4 7-18
Meeting Report | Published on 11 Apr 2011

Stochastic Resonance Activity Influences Serum Tryptophan Metabolism in Healthy Human Subjects
Berthold Kepplinger, Halina Baran, Brenda Sedlnitzky-Semler, Nagy-Roland Badawi and Helene Erhart
International Journal of Tryptophan Research 2011:4 49-60
Original Research | Published on 08 Nov 2011

Quinolinic Acid, an Endogenous Molecule Combining Excitotoxicity, Oxidative Stress and Other Toxic Mechanisms
Verónica Pérez-De La Cruz, Paul Carrillo-Mora and Abel Santamaría
International Journal of Tryptophan Research 2012:5 1-8
Review | Published on 23 Feb 2012

Role of the NMDA-receptor in Prepulse Inhibition in the Rat
Klas Linderholm, Susan Powell, Elin Olsson, Maria Holtze, Ralph Snodgrass and Sophie Erhardt
International Journal of Tryptophan Research 2010:3 1-12
Original Research | Published on 12 Feb 2010

Endogenous Kynurenine Aminotransferases Inhibitor is Proposed to Act as “Glia Depressing Factor” (GDF)
Halina Baran, Berthold Kepplinger and Markus Draxler
International Journal of Tryptophan Research 2010:3 13-22
Original Research | Published on 11 May 2010

Indoleamine 2,3-Dioxygenase in Human Hematopoietic Stem Cell Transplantation
Birgit Jürgens, Julia Raberger, Dietmar Fuchs and Andreas Heitger
International Journal of Tryptophan Research 2010:3 77-90
Review - Special Issue | Published on 10 Jun 2010

Implication of Tryptophan 2,3-Dioxygenase and its Novel Variants in the Hippocampus and Cerebellum During the Developing and Adult Brain
Masaaki Kanai, Hiroshi Funakoshi and Toshikazu Nakamura
International Journal of Tryptophan Research 2010:3 141-149
Meeting Report | Published on 23 Jul 2010

Dedication: Paolo Guidetti
Robert Schwarcz
International Journal of Tryptophan Research 2009:2 21-22
Published on 16 Feb 2009

Rapid Isocratic Liquid Chromatographic Separation and Quantification of Tryptophan and Six kynurenine Metabolites in Biological Samples with Ultraviolet and Fluorimetric Detection
Abdulla A-B Badawy and Christopher J Morgan
International Journal of Tryptophan Research 2010:3 175-186
Original Research | Published on 08 Dec 2010

Alzheimer’s and Seizures: Interleukin-18, Indoleamine 2,3-Dioxygenase and Quinolinic Acid
Anderson G and Ojala JO
International Journal of Tryptophan Research 2010:3 169-173
Hypothesis | Published on 15 Oct 2010

A Brief Historic Overview of Clinical Disorders Associated with Tryptophan: The Relevance to Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM)
Adele Blankfield
International Journal of Tryptophan Research 2012:5 27-32
Letter to Editor | Published on 17 Sep 2012

Kynurenine Pathway in Skin Cells: Implications for UV-Induced Skin Damage
Diba Sheipouri, Nady Braidy, and Gilles J. Guillemin,
International Journal of Tryptophan Research 2012:5 15-25
Short Review | Published on 03 Jul 2012

L-Tryptophan Production by Auxotrophic and Analogue Resistant Mutants of Aureobacterium flavescens
A. Roy and S.K. Mukhopadhyay
International Journal of Tryptophan Research 2011:4 39-46
Original Research | Published on 29 May 2011

Specificity of the Acute Tryptophan and Tyrosine Plus Phenylalanine Depletion and Loading Tests I. Review of Biochemical Aspects and Poor Specificity of Current Amino Acid Formulations
Abdulla A.-B. Badawy, Donald M. Dougherty and Dawn M. Richard
International Journal of Tryptophan Research 2010:3 23-34
Original Research | Published on 02 Jun 2010

Specificity of the Acute Tryptophan and Tyrosine Plus Phenylalanine Depletion and Loading Tests Part II: Normalisation of the Tryptophan and the Tyrosine Plus Phenylalanine to Competing Amino Acid Ratios in a New Control Formulation
Abdulla A.-B. Badawy, Donald M. Dougherty and Dawn M. Richard
International Journal of Tryptophan Research 2010:3 35-47
Original Research | Published on 09 Jun 2010

Role of NAD+, Oxidative Stress, and Tryptophan Metabolism in Autism Spectrum Disorders
Musthafa Mohamed Essa, Selvaraju Subash, Nady Braidy, Samir Al-Adawi, Chai K Lim, Tamilarasan Manivasagam and Gilles J Guillemin
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 15-28
Review | Published on 21 Jul 2013

Kynurenine Pathway Hypothesis: The Nature of the Chronic Fatigue Syndrome (CFS) Revisited
Adele Blankfield
International Journal of Tryptophan Research 2011:4 47-48
Letter to Editor | Published on 31 Jul 2011

Proteasomal Degradation of Indoleamine 2,3-Dioxygenase  in CD8+ Dendritic Cells is Mediated by Suppressor of Cytokine Signaling 3 (SOCS3)
Maria T. Pallotta, Ciriana Orabona, Claudia Volpi, Ursula Grohmann, Paolo Puccetti and Francesca Fallarino
International Journal of Tryptophan Research 2010:3 91-97
Original Research - Special Issue | Published on 10 Jun 2010

Accelerated Tryptophan Degradation Predicts Poor Survival in Trauma and Sepsis Patients
Martin Ploder, Andreas Spittler, Katharina Kurz, Gabriele Neurauter, Linda E. Pelinka, Erich Roth and Dietmar Fuchs
International Journal of Tryptophan Research 2010:3 61-67
Original Research - Special Issue | Published on 10 Jun 2010

Kynurenic Acid Metabolism in Various Types of Brain Pathology in HIV-1 Infected Patients
H. Baran, J.A. Hainfellner and B. Kepplinger
International Journal of Tryptophan Research 2012:5 49-64
Original Research | Published on 13 Dec 2012

A Jerte Valley Cherry-Based Product as a Supply of Tryptophan
María Garrido, Javier Espino, Antonio F. Toribio-Delgado, Javier Cubero, Juan I. Maynar-Mariño, Carmen Barriga, Sergio D. Paredes and Ana B. Rodríguez
International Journal of Tryptophan Research 2012:5 9-14
Original Research | Published on 16 Apr 2012

Fate of Dietary Tryptophan in Young Japanese Women
Chiaki Hiratsuka, Tsutomu Fukuwatari and Katsumi Shibata
International Journal of Tryptophan Research 2012:5 33-47
Original Research | Published on 30 Oct 2012

Editorial ISTRY Special Issue
Gilles J. Guillemin
International Journal of Tryptophan Research 2010:3 49-50
Editorial - Special Issue | Published on 10 Jun 2010

Kynurenic Acid in the Digestive System—New Facts, New Challenges
Michal P. Turski, Monika Turska, Piotr Paluszkiewicz, Jolanta Parada-Turska and Gregory F. Oxenkrug
International Journal of Tryptophan Research 2013:6 47-55
Consise Review | Published on 04 Sep 2013

Transport of Kynurenic Acid by Rat Organic Anion Transporters rOAT1 and rOAT3: Species Difference between Human and Rat in OAT1
Yuichi Uwai, Hiroaki Hara and Kikuo Iwamoto
International Journal of Tryptophan Research 2013:6 1-6
Original Research | Published on 17 Feb 2013

The Kynurenine Pathway in Stem Cell Biology
Simon P. Jones, Gilles J. Guillemin and Bruce J. Brew
International Journal of Tryptophan Research 2013:6 57-66
Review | Published on 15 Sep 2013

Big Brains, Meat, Tuberculosis, and the Nicotinamide Switches: Co-Evolutionary Relationships with Modern Repercussions?
Adrian C. Williams and Robin I.M. Dunbar
International Journal of Tryptophan Research 2013:6 73-88
Perspective | Published on 15 Oct 2013

Characterization of the Kynurenine Pathway and Quinolinic Acid Production in Macaque Macrophages
Chai K. Lim, Margaret M.C. Yap, Stephen J. Kent, Gabriel Gras, Boubekeur Samah, Jane C. Batten, Robert De Rose, Benjamin Heng, Bruce J. Brew, and Gilles J. Guillemin
International Journal of Tryptophan Research 2013:6 7-19
Original Research | Published on 15 May 2013

Kynurenine Pathway Pathologies: do Nicotinamide and Other Pathway Co-Factors have a Therapeutic Role in Reduction of Symptom Severity, Including Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM)
Adele Blankfield
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 39-45
Commentary | Published on 21 Jul 2013

Determination of L-tryptophan and L-kynurenine in Human Serum by using LC-MS after Derivatization with (R)-DBD-PyNCS
Hayato Ohashi, Hideaki Iizuka, Shunsuke Yoshihara, Hayato Otani, Misato Kume, Kiyomi Sadamoto, Hideaki Ichiba and Takeshi Fukushima
International Journal of Tryptophan Research 2013:6 (Suppl. 1) 9-14
Original Research | Published on 21 Jul 2013