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Drug Target Insights



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Editor in Chief: Anuj Chauhan

Indexing & Databases: Pubmed, DOAJ, EBSCO Academic Search International, EMBase, Gale Academic OneFile, Gale Health Reference Centre, Gale InfoTrac Custom Journals, ProQuest Health & Medical Complete, Pubmed Central, Scopus

Journal Directories: EBSCO A-Z, HINARI, JournalTOCs

Processing Speed: High quality, constructive peer review and rapid editorial decision within an average of four weeks.

ISSN: 1177-3928

H Index: 5 more info



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2015:9

7-NI and ODQ Disturbs Memory in the Elevated Plus Maze, Morris Water Maze, and Radial Arm Maze Tests in Mice
Oguz Mutlu, Furuzan Akar, Ipek Komsuoglu Celikyurt, Pelin Tanyeri, Guner Ulak and Faruk Erden
Drug Target Insights 2015:9 1-8
Original research | Published on 04 Mar 2015



Medicinal Plants: A Potential Source of Compounds for Targeting Cell Division
Ihsan N. Zulkipli, Sheba R. David, Rajan Rajabalaya and Adi Idris
Drug Target Insights 2015:9 9-19
Original research | Published on 15 Jun 2015



Basal Plasma Levels of Copeptin are Elevated in Inactive Inflammatory Bowel Disease after Bowel Resection
Bodil Ohlsson and Olle Melander
Drug Target Insights 2015:9 21-27
Original research | Published on 13 Jul 2015



2014:8

In Silico Molecular Characterization of Cysteine Protease YopT from Yersinia pestis by Homology Modeling and Binding Site Identification
Md. Anayet Hasan, S. M. Alauddin, Mohammad Al Amin, Suza Mohammad Nur and Adnan Mannan
Drug Target Insights 2014:8 1-9
Original research | Published on 13 Jan 2014



The Antidepressant Agomelatine Improves Memory Deterioration and Upregulates CREB and BDNF Gene Expression Levels in Unpredictable Chronic Mild Stress (UCMS)-Exposed Mice
Esen Gumuslu, Oguz Mutlu, Deniz Sunnetci, Guner Ulak, Ipek K. Celikyurt, Naci Cine, Furuzan Akar, Hakan Savli and Faruk Erden
Drug Target Insights 2014:8 11-21
Original research | Published on 05 Mar 2014



Effects of Zaprinast and Rolipram on Olfactory and Visual Memory in the Social Transmission of Food Preference and Novel Object Recognition Tests in Mice
Furuzan Akar, Oguz Mutlu, Ipek K. Celikyurt, Emine Bektas, Mehmet H. Tanyeri, Guner Ulak, Pelin Tanyeri and Faruk Erden
Drug Target Insights 2014:8 23-29
Original research | Published on 29 Apr 2014



Molecular and Kinetic Characterization of Babesia microti Gray Strain Lactate Dehydrogenase as a Potential Drug Target
Patrick Vudriko, Tatsunori Masatani, Shinuo Cao, Mohamad Alla Terkawi, Ketsarin Kamyingkird, Ahmed A. Mousa, Paul F. Adjou Moumouni, Yoshifumi Nishikawa and Xuenan Xuan
Drug Target Insights 2014:8 31-38
Original research | Published on 28 Jul 2014



Febuxostat for Hyperuricemia in Patients with Advanced Chronic Kidney Disease
Tetsu Akimoto, Yoshiyuki Morishita, Chiharu Ito, Osamu Iimura, Sadao Tsunematsu, Yuko Watanabe, Eiji Kusano and Daisuke Nagata
Drug Target Insights 2014:8 39-43
Original research | Published on 13 Aug 2014



The Expression of Serum Antibodies Against Gonadotropin-releasing Hormone (GnRH1), Progonadoliberin-2, Luteinizing Hormone (LH), and Related Receptors in Patients with Gastrointestinal Dysfunction or Diabetes Mellitus
Bodil Roth, Kerstin Berntorp and Bodil Ohlsson
Drug Target Insights 2014:8 45-50
Original research | Published on 10 Nov 2014



Genome-wide Analysis of Mycoplasma hominis for the Identification of Putative Therapeutic Targets
Md. Masud Parvege, Monzilur Rahman and Mohammad Shahnoor Hossain
Drug Target Insights 2014:8 51-62
Original research | Published on 09 Dec 2014



2013:7

Antibodies Against Gonadotropin-Releasing Hormone in Patients with Posterior Laryngitis
Hillevi Pendleton, Ragnar Alm, Gunilla Nordin Fredrikson, and Bodil Ohlsson
Drug Target Insights 2013:7 1-8
Original research | Published on 28 Jan 2013



Impact of Hepatocyte Growth Factor on Skeletal Myoblast Transplantation Late After Myocardial Infarction
Stacy B. O’Blenes, Audrey W. Li, Chris Bowen, Drew DeBay, Mohammed Althobaiti and James Clarke
Drug Target Insights 2013:7 9-17
Original research | Published on 06 May 2013



Microscopic Colitis is Associated with Several Concomitant Diseases
Bodil Roth, Jonas Manjer and Bodil Ohlsson
Drug Target Insights 2013:7 19-25
Original research | Published on 11 Aug 2013



P-glycoprotein Inhibition for Optimal Drug Delivery
Md. Lutful Amin
Drug Target Insights 2013:7 27-34
Original research | Published on 19 Aug 2013



Hsp60 Chaperonin Acts as Barrier to Pharmacologically Induced Oxidative Stress Mediated Apoptosis in Tumor Cells with Differential Stress Response
Upasana Sarangi, Manish Kumar Singh, Kanugovi Vijaya Vittal Abhijnya, Lebaka Prasanna Anjaneya Reddy, Badabagni Siva Prasad, Vikrant Vinay Pitke, Khanderao Paithankar and Amere Subbarao Sreedhar
Drug Target Insights 2013:7 35-51
Original research | Published on 01 Sep 2013



Microscopic Colitis and Reproductive Factors Related to Exposure to Estrogens and Progesterone
Bodil Roth, Jonas Manjer and Bodil Ohlsson
Drug Target Insights 2013:7 53-62
Original research | Published on 07 Oct 2013



2012:6

Resveratrol Targeting of Carcinogen-Induced Brain Endothelial Cell Inflammation Biomarkers MMP-9 and COX-2 is Sirt1-Independent
Borhane Annabi, Simon Lord-Dufour, Amélie Vézina and Richard Béliveau
Drug Target Insights 2012:6 1-11
Original research | Published on 11 Apr 2012



Expression of Luteinizing Hormone Receptor in the Gastrointestinal Tract in Patients with and without Dysmotility
Oskar Hammar, Béla Veress, Agneta Montgomery and Bodil Ohlsson
Drug Target Insights 2012:6 13-18
Original research | Published on 23 Apr 2012



17AAG Treatment Accelerates Doxorubicin Induced Cellular Senescence: Hsp90 Interferes with Enforced Senescence of Tumor Cells
Upasana Sarangi, Khande Rao Paithankar, Jonnala Ujwal Kumar, Vaidyanathan Subramaniam and Amere Subbarao Sreedhar
Drug Target Insights 2012:6 19-39
Original research | Published on 06 Aug 2012



Drug Target Exploitable Structural Features of Adenylyl Cyclase Activity in Schistosoma mansoni
Andreas N. Mbah, Henri L. Kamga, Omotayo R. Awofolu and Raphael D. Isokpehi
Drug Target Insights 2012:6 41-58
Original research | Published on 24 Oct 2012



2011:5

The Effect of Valproic Acid on Mesenchymal Pluripotent Cell Proliferation and Differentiation in Extracellular Matrices
Yuji Hatakeyama, Junko Hatakeyama, Atsushi Takahashi, Kyoko Oka, Eichi Tsuruga, Tetsuichiro Inai and Yoshihiko Sawa
Drug Target Insights 2011:5 1-9
Original research | Published on 22 Mar 2011



Repercussion of Mitochondria Deformity Induced by Anti-Hsp90 Drug 17AAG in Human Tumor Cells
Chaturvedi Vishal, Jonnala Ujwal Kumar, Cherukuvada Veera Brahmendra Swamy, Rangaraj Nandini, Gunda Srinivas, Rathinam Kumaresan, Singh Shashi and Amere Subbarao Sreedhar
Drug Target Insights 2011:5 11-32
Original research | Published on 07 Jun 2011 | Highly accessed (previous month)



Predictors of Virologic Failure in HIV/AIDS Patients Treated with Highly Active Antiretroviral Therapy in Brasília, Brazil During 2002–2008
Edson José Monteiro Bello, Amabel Fernandes Correia, José Ricardo Pio Marins, Edgar Merchan-Hamann and Luis Isamu Barros Kanzaki
Drug Target Insights 2011:5 33-41
Original research | Published on 24 Nov 2011



2009:4

A Model for NAD(P)H:Quinoneoxidoreductase 1 (NQO1) Targeted Individualized Cancer Chemotherapy
Asher Begleiter, Nadia El-Gabalawy, Laurie Lange, Marsha K. Leith, Lynn J. Guziec and Frank S. Guziec Jr
Drug Target Insights 2009:4 1-8
Original research | Published on 15 Jan 2009



2008:3

Cytokine, Chemokine and Immune Activation Pathway Profiles in Celiac Disease: An Immune System Activity Screening by Expression Macroarrays
José A. Garrote, Emma Gómez, Alberto J. León, David Bernardo, Carmen Calvo, Luis Fernández-Salazar, Alfredo Blanco-Quirós and Eduardo Arranz
Drug Target Insights 2008:3 1-11
Original research | Published on 21 Jan 2008



Targeting Gallium to Cancer Cells through the Folate Receptor
Nerissa Viola-Villegas, Anthony Vortherms and Robert P. Doyle
Drug Target Insights 2008:3 13-25

Original research | Published on 01 Mar 2008



New-Onset Diabetes Mellitus Among Parkinsonian Patients Treated with Long-term Quetiapine
Hubert H. Fernandez, Katie M. McCown, Janet Romrell, Martha E. Trieschmann, Joseph H. Friedman, Charles E. Jacobson IV and Michael S. Okun
Drug Target Insights 2008:3 27-29
Original research | Published on 18 Mar 2008



Evidence of a Novel Gene from Aeromonas hydrophila Encoding a Putative Siderophore Receptor Involved in Bacterial Growth and Survival
Shaw-Wei D. Tsen
Drug Target Insights 2008:3 31-36
Original research | Published on 18 Mar 2008



Targeting Insulin-Like Growth Factor-1 Signaling into the Central Nervous System for Promoting Myelin Repair
Nadine Wilczak, Jacques De Keyser and Daniel Chesik
Drug Target Insights 2008:3 37-44
Original research | Published on 18 Apr 2008



Therapies to Increase ApoA-I and HDL-Cholesterol Levels
William M. Brown and Fabrizio S. Chiacchia
Drug Target Insights 2008:3 45-54
Original research | Published on 23 Apr 2008



Use of Proteomics Analysis for Molecular Precision Approaches in Cancer Therapy
Yuqiao Shen, Neil N. Senzer and John J. Nemunaitis
Drug Target Insights 2008:3 55-66
Original research | Published on 23 Apr 2008



The Beta3 499–513 Peptide Region is Required for AlphaIIb/ Beta3 Active Complex Formation and Fibrinogen Binding
Virginia Woo-Rasberry and Thomas M. Chiang
Drug Target Insights 2008:3 67-76
Original research | Published on 28 Apr 2008



Memantine: Reality and Potentiality
Rita Moretti, Paola Torre, Cristina Vilotti, Davide Manganaro, Luca Zanet and Rodolfo M. Antonello
Drug Target Insights 2008:3 77-85
Original research | Published on 08 May 2008



Thrombophilia
Maurizio Zangari, Francesca Elice, Guido Tricot and Louis Fink
Drug Target Insights 2008:3 87-97
Original research | Published on 16 Apr 2008



Recent Advancements in Targeted Delivery of Therapeutic Molecules in Neurodegenerative Disease - Spinocerebellar Ataxia - Opportunities and Challenges
Satya Prakash and Meenakshi Malhotra
Drug Target Insights 2008:3 99-117
Original research | Published on 02 May 2008



Live Typhoid Vaccine for IBD-Patients—Well Tolerated and with Possible Therapeutic Effect
Gunnar Nysæter and Arnold Berstad
Drug Target Insights 2008:3 119-123
Original research | Published on 16 May 2008



Study of Alkylglycerol Containing Shark Liver Oil: a Physico Chemical Support for Biological Effect?
Jean-Claude Debouzy, David Crouzier, Bertrand Lefebvre and Vincent Dabouis
Drug Target Insights 2008:3 125-135
Original research | Published on 28 May 2008



The Target of 5-Lipoxygenase is a Novel Strategy over Human Urological Tumors than the Target of Cyclooxygenase-2
Masahide Matsuyama and Rikio Yoshimura
Drug Target Insights 2008:3 137-151

Original research | Published on 13 Jun 2008



The Toxicity of a Chemically Synthesized Peptide Derived from Non-Integrin Platelet Collagen Receptors
Thomas M. Chiang and V. Woo-Rasberry
Drug Target Insights 2008:3 153-159
Original research | Published on 13 Aug 2008



2007:2

Long-term L-Carnitine Administration reduces Erythropoietin Resistance in Chronic Hemodialysis Patients with Thalassemia Minor
Biagio R. Di Iorio, Pasquale Guastaferro, Nicola Cillo, Emanuele Cucciniello and Vincenzo Bellizzi
Drug Target Insights 2007:2 1-7
Original research | Published on 24 Jan 2007



Cyclophilin and Viruses: Cyclophilin as a Cofactor for Viral Infection and Possible Anti-Viral Target
Koichi Watashi and Kunitada Shimotohno
Drug Target Insights 2007:2 9-18
Original research | Published on 05 Feb 2007



Effect of Ribavirin Alone or Combined with Silymarin on Carbon Tetrachloride Induced Hepatic Damage in Rats
Omar M.E. Abdel Salam, Amany A. Sleem, Enayat A. Omara and Nabila S. Hassan
Drug Target Insights 2007:2 19-27
Original research | Published on 07 Feb 2007



Modulation of Visceral Nociception, Inflammation and Gastric Mucosal Injury by Cinnarizine
Omar M.E. Abdel-Salam
Drug Target Insights 2007:2 29-38
Original research | Published on 12 Feb 2007



The Adaptogens Rhodiola and Schizandra Modify the Response to Immobilization Stress in Rabbits by Suppressing the Increase of Phosphorylated Stress-activated Protein Kinase, Nitric Oxide and Cortisol
Alexander Panossian, Marina Hambardzumyan, Areg Hovhanissyan and Georg Wikman
Drug Target Insights 2007:2 39-54
Original research | Published on 16 Feb 2007



Accelerators of Osteogenesis by Recombinant Human Bone Morphogenetic Protein-2
Yasunori Okubo, Kenji Kusumoto and Kazuhisa Bessho
Drug Target Insights 2007:2 55-60
Original research | Published on 21 Feb 2007



Electrocardiographic Findings in Acutely and Chronically T. cruzi-infected Mice Treated by a Phenyl-Substituted Analogue of Furamidine DB569
Elen M. de Souza, Gabriel M. Oliveira and Maria de Nazaré C. Soeiro
Drug Target Insights 2007:2 61-69
Original research | Published on 05 Mar 2007



Targeting Receptors, Transporters and Site of Absorption to Improve Oral Drug Delivery
J.H. Hamman, P.H. Demana and E.I. Olivier
Drug Target Insights 2007:2 71-81
Original research | Published on 06 Mar 2007



Phospholipase A2 Activates Hemostasis
Thomas W. Stief
Drug Target Insights 2007:2 83-96
Original research | Published on 22 Mar 2007



Cardiovascular Pharmacology of Sinomenine: The Mechanical and Electropharmacological Actions
Seiichiro Nishida and Hiroyasu Satoh
Drugs Target Insights 2007:2 97-104
Original research | Published on 18 Apr 2007



Circulating Vascular Endothelial Growth Factor (VEGF) Levels in Advanced Stage Cancer Patients Compared to Normal Controls and Diabetes Mellitus Patients with Critical Ischemia
Yoka H. Kusumanto, Coby Meijer, Wendy Dam, Nanno H. Mulder and Geke A.P. Hospers
Drug Target Insights 2007:2 105-109
Original research | Published on 18 May 2007



Endothelial Dysfunction, Erectile Dysfunction and Phosphodiesterase 5 Inhibitors. An Update of the Current Data and Future Perspectives
Angelis Konstantinopoulos, Konstantinos Giannitsas, Spiros Raptis and Petros Perimenis
Drug Target Insights 2007:2 111-117
Original research | Published on 29 May 2007



The Relationship of Arginine Deprivation, Argininosuccinate Synthetase and Cell Death in Melanoma
Niramol Savaraj, Chunjing Wu, Marcus Tien Kuo, Min You, Medhi Wangpaichitr, Carlos Robles, Seth Spector and Lynn Feun
Drug Target Insights 2007:2 119-128
Original research | Published on 15 Jun 2007



Trypanothione Reductase: A Viable Chemotherapeutic Target for Antitrypanosomal and Antileishmanial Drug Design
M. Omar F. Khan
Drug Target Insights 2007:2 129-146
Original research | Published on 19 Jun 2007



Polymeric Nanoparticles, Nanospheres and Nanocapsules, for Cutaneous Applications
Sílvia S. Guterres, Marta P. Alves and Adriana R. Pohlmann
Drug Target Insights 2007:2 147-157

Original research | Published on 11 Jul 2007



Targeting Human Immunodeficiency Virus Type 1 Assembly, Maturation and Budding
Johanna Wapling, Seema Srivastava, Miranda Shehu-Xhilaga and Gilda Tachedjian
Drug Target Insights 2007:2 159-182
Original research | Published on 20 Jul 2007



Delivery Systems for In Vivo use of Nucleic Acid Drugs
Resende R.R, Torres H.A.M, Yuahasi K.K, Majumder P and Ulrich H
Drug Target Insights 2007:2 183-196
Original research | Published on 09 Aug 2007



Targeted Brain Tumor Treatment: Current Perspectives
Ningaraj N.S, Salimath B.P, Sankpal U.T, Perera R and Vats T
Drug Target Insights 2007:2 197-207
Original research | Published on 17 Aug 2007



Use and Safety of Anthroposophic Medications for Acute Respiratory and Ear Infections: A Prospective Cohort Study
Harald J. Hamre, Anja Glockmann, Michael Fischer, David S. Riley, Erik Baars and Helmut Kiene
Drug Target Insights 2007:2 209-219
Original research | Published on 14 Sep 2007



Effect of live Salmonella Ty21a in Dextran Sulfate Sodium-induced Colitis
Gunnar Nysoeter, Kari Erichsen, Anne Marita Milde, Eva Colás, Einar Kristoffersen and Arnold Berstad
Drug Target Insights 2007:2 221-228
Original research | Published on 18 Sep 2007



New Insights into the Understanding of Gastrointestinal Dysmotility
Bodil Ohlsson and Sabina Janciauskiene
Drug Target Insights 2007:2 229-237
Original research | Published on 25 Sep 2007



Platelet-Derived Growth Factor as a Therapeutic Target for Systemic Autoimmune Diseases
Hideto Kameda, Miyuki Suzuki and Tsutomu Takeuchi
Drug Target Insights 2007:2 239-247
Original research | Published on 30 Oct 2007



Effects of Ascorbic Acid, Alpha-Tocopherol and Allopurinol on Ischemia-Reperfusion Injury in Rabbit Skeletal Muscle: An Experimental Study
Bilgehan Erkut, Ahmet Özyazıcıoğlu, Bekir Sami Karapolat, Cevdet Uğur Koçoğulları, Sait Keles, Azman Ateş, Cemal Gundogdu, Hikmet Kocak
Drug Target Insights 2007:2 249-258
Original research | Published on 21 Nov 2007



2006:1

Neurogenesis and Alzheimer's Disease
Philippe Taupin
Drug Target Insights 2006:1 1-4
Original research | Published on 19 Oct 2006



Inhibition of Intrinsic Thrombin Generation
Thomas W. Stief
Drug Target Insights 2006:1 5-10
Original research | Published on 23 Oct 2006



Neurogenesis and The Effect of Antidepressants
Philippe Taupin
Drug Target Insights 2006:1 13-17
Original research | Published on 26 Oct 2006



Modification of Monoaminergic Activity by MAO Inhibitors Influences Methamphetamine Actions
Junichi Kitanaka, Nobue Kitanaka and Motohiko Takemura
Drug Target Insights 2006:1 19-28
Original research | Published on 09 Nov 2006



The Way that PEGyl-DSPC Liposomal Doxorubicin Particles Penetrate into Solid Tumor Tissue
Xing Qing Pan, Susie Jones and Karen Cox
Drug Target Insights 2006:1 29-34
Original research | Published on 12 Dec 2006





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