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Nutrition and Metabolic Insights

Synopsis: An open access, peer reviewed electronic journal that covers nutrition and metabolism.


Indexing: Indexed by CAS. Pubmed indexing for NIH-funded research.

Processing time: Decision in 2 weeks for 90% of papers.

Visibility: Most popular article read 500+ times.

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About this journal

ISSN: 1178-6388


Aims and scope:

Nutrition and Metabolic Insights is a peer-reviewed, open-access online journal focused on all aspects of nutrition and metabolism. This encompasses nutrition, including the biochemistry of metabolism, exercise and associated physical processes and also includes clinical articles that relate to metabolism, such as obesity, lipidemias and diabetes. It includes research at the molecular, cellular and organismal levels.

Other areas of interest include gene-nutrient interactions, the effects of hormones, models of metabolic function, macronutrient interactions, outcomes of changes in diet, and pathophysiology.

Editorial standards and procedures:

Submissions, excluding editorials, letters to the editor and dedications, will be peer reviewed by two reviewers.  Reviewers are required to provide fair, balanced and constructive reports.  

Under our Fairness in Peer Review Policy authors may appeal against reviewers' recommendations which are ill-founded, unobjective or unfair.  Appeals are considered by the Editor in Chief or Associate Editor.

Papers are not sent to peer reviewers following submission of a revised manuscript. Editorial decisions on re-submitted papers are based on the author's response to the initial peer review report.

Indexing:

This journal is indexed by:

  • CAS

National Institutes of Health Public Access Policy compliant:

As of April 7 2008, the US NIH Public Access Policy requires that all peer reviewed articles resulting from research carried out with NIH funding be deposited in the Pubmed Central archive.

If you are an NIH employee or grantee Libertas Academica will ensure that you comply with the policy by depositing your paper at Pubmed Central on your behalf. 



Editor in Chief's call for papers
 
 
 


Femoral Cortical Bone Mineral Density and Biomechanical Properties in Sheep Consuming an Acidifying Diet

Authors: Eileen S. Hackett, Jennifer M. MacLeay, Mike Green, R. Mark Enns, Carola L. Pechey, Clifford M. Les and A. Simon Turner
Publication Date: 10 Dec 2008
Nutrition and Metabolic Insights 2009:2 11-16

Eileen S. Hackett1, Jennifer M. MacLeay1, Mike Green1, R. Mark Enns2, Carola L. Pechey3, Clifford M. Les3 and A. Simon Turner1

1Small Ruminant Comparative Orthopaedic Laboratory, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523, U.S.A. 2Department of Animal Science, College of Agricultural Sciences, Colorado State University, Fort Collins, Colorado 80523, U.S.A. 3Bone and Joint Center, Henry Ford Hospital, Detroit MI 48202, U.S.A. Source of funding: Colorado State University NASA Research Seed Grant.

Abstract

Dietary acidity is a likely contributor to the development of osteoporosis. Dietary acidosis in an ovine model has effects on trabecular bone that have been previously shown to mimic human osteoporosis. Effects on cortical bone using this model have not been investigated. The objective of this study was to examine the effects of dietary acidosis on cortical bone mineral density and material properties. Skeletally mature ovariectomized (OVX) sheep consumed either a normal diet (ND) or a metabolic acidosis diet (MA) for 6 or 12 months. Whole femoral and cortical bone beam BMD was determined using dual energy x-ray absorptiometry (DEXA). Beams were then subjected to three point flexure monotonically to failure to determine strength and modulus and then ashed to determine percent mineralization. Femoral BMD in adult OVX ND 6 mo sheep was significantly greater than those in the non-OVX ND group. The BMD in the MA groups was lower than the control non-OVX ND group. Cortical beams had significantly decreased modulus in all MA and OVX groups when compared with the non-OVX ND group and a tendency towards decreased strength in all groups with significance only in the OVX ND 6 mo sheep. Percent mineralization increased in MA and OVX groups when compared to the non-OVX ND group and was significantly increased in the OVX ND 6 mo and OVX MA 12 mo groups. A significant correlation was seen between BMD of the beam and breaking strength and modulus. Dietary acidity impacts cortical bone and results in reduced material properties that may contribute to failure.



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