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Clinical Medicine: Gastroenterology

Synopsis: An open access, peer reviewed electronic journal that covers diagnosis, management and prevention of gastroenterological conditions.


Indexing: 5 major databases. Pubmed indexing for NIH-funded research.

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About this journal

ISSN: 1178-119X


Aims and scope:

Clinical Medicine: Gastroenterology is an international, open access, peer reviewed journal which considers manuscripts on all aspects of the diagnosis, management and prevention of gastroenterological disorders, in addition to related genetic, pathophysiological and epidemiological topics.

Editorial standards and procedures:

Submissions, excluding editorials, letters to the editor and dedications, will be peer reviewed by two reviewers.  Reviewers are required to provide fair, balanced and constructive reports.  

Under our Fairness in Peer Review Policy authors may appeal against reviewers' recommendations which are ill-founded, unobjective or unfair.  Appeals are considered by the Editor in Chief or Associate Editor.

Papers are not sent to peer reviewers following submission of a revised manuscript. Editorial decisions on re-submitted papers are based on the author's response to the initial peer review report.

Indexing:

This journal is indexed by the following services:

  • Google Scholar
  • DOAJ
  • CAS
  • SCOPUS
  • Embase

National Institutes of Health Public Access Policy compliant:

As of April 7 2008, the US NIH Public Access Policy requires that all peer reviewed articles resulting from research carried out with NIH funding be deposited in the Pubmed Central archive.

If you are an NIH employee or grantee Libertas Academica will ensure that you comply with the policy by depositing your paper at Pubmed Central on your behalf. 



Editor in Chief's call for papers
 
 
 


Effects of Seal Oil on Meal-Induced Symptoms and Gastric Accommodation in Patients with Subjective Food Hypersensitivity: A Pilot Study

Authors: Kine Gregersen, Ragna A. Lind, Tormod Bjørkkjær, Livar Frøyland, Arnold Berstad and Gülen Arslan Lied
Publication Date: 05 Nov 2008
Clinical Medicine: Gastroenterology 2008:1 33-41

Kine Gregersen1,2, Ragna A. Lind2, Tormod Bjørkkjær1,3, Livar Frøyland1, Arnold Berstad2 and Gülen Arslan Lied2

1National Institute of Nutrition and Seafood Research (NIFES), PO Box 2029 Nordnes, N-5817 Bergen, Norway. 2Institute of Medicine, Haukeland University Hospital, University of Bergen, N-5021 Bergen, Norway. 3Department of Biomedicine, University of Bergen, N-5009 Bergen, Norway.

Abstract

Background:  Food hypersensitivity is a prevalent condition with poorly characterized underlying mechanisms. In the present pilot study we investigated effects of seal oil and soy oil on meal-induced symptoms and gastric accommodation in patients with subjective food hypersensitivity (FH). Single dose experiment: On three consecutive days, 10 mL of seal oil, soy oil, or saline were randomly administered into the duodenum of 10 patients with subjective FH and 10 healthy volunteers through a nasoduodenal feeding tube 10–20 minutes before the ingestion of a test meal. Short-term treatment study: 24 patients with subjective FH were randomly allocated to 10 days’ treatment with either 10 mL of seal or soy oil, self-administrated through an indwelling nasoduodenal feeding tube, 3 times daily. In both experiments meal-induced abdominal symptoms and gastric accommodation were measured by visual analogue scales and external ultrasound respectively.

Results:  Symptoms and gastric accommodation were not significantly influenced by single doses of seal or soy oil. When given daily for 10 days, seal oil, but not soy oil, reduced total symptom scores significantly (P = 0.03). The symptomatic improvement was not associated with improvements in gastric accommodation.

Conclusion:  Daily administration of seal oil may benefit patients with subjective FH. The beneficial effect of seal oil in patients with subjective FH cannot be ascribed to improved gastric accommodation.

Categories: Gastroenterology


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