Annamaria Molino¹, Monica Giovannini², Rocco Micciolo³, Alessandra Auriemma¹, Elena Fiorio¹, Antonio Santo¹ and Gian Luigi Cetto¹

¹Department of Medical Oncology, University of Verona, Verona, Italy. ²Department of Medical Oncology, San Raffaele Hospital, Milan, Italy. ³Institute of Statistics, University of Trento, Trento, Italy.

Abstract

In 125 early breast cancer patients who underwent multiple bone marrow aspirates, there was no significant difference in terms of disease-free and overall survival after a median follow-up of 163 months between the patients with or without micrometastasis at the time of primary surgery. However, when the time-dependent evolution of the bone marrow aspirates was taken into account, some evidence for a longer disease-free and overall survival was found for the patients with negative bone marrow.

Discussion
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