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Publication Date: 16 Feb 2012
Type: Case report
Journal: Clinical Medicine Insights: Case Reports
Citation: Clinical Medicine Insights: Case Reports 2012:5 13-17
doi: 10.4137/CCRep.S8790
We report a patient with psoriatic arthritis (PsA) who was successfully treated with adalimumab even while under hemodialysis therapy for associated chronic renal failure. Flow cytometry of circulating lymphocytes revealed an obvious decrease in both Th1 and Th17 cells after starting adalimumab. The latter returned to the pretreatment level in the course of adalimumab therapy, while the former did not. Adalimumab is a potent therapeutic option for PsA patients with chronic renal failure on hemodialysis, and Th1 in peripheral blood may reflect the disease activity.
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