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Clinical Medicine: Circulatory, Respiratory and Pulmonary Medicine

Synopsis: An open access, peer reviewed electronic journal that covers circulatory, respiratory and pulmonary medicine.


Indexing: 5 major databases. Pubmed indexing for NIH-funded research.

Processing time: Decision in 2 weeks for 90% of papers.

Visibility: Most popular article read 900+ times.

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About this journal

ISSN: 1178-1157


Aims and scope:

Clinical Medicine: Circulatory, Respiratory and Pulmonary Medicine is an international, open access, peer reviewed journal which considers manuscripts on all aspects of circulatory, respiratory or pulmonary medicine. The journal welcomes articles on all aspects of the prevention, diagnosis and management of all associated disorders in addition to related genetic, pathophysiological and epidemiological topics.

The following topics are of specific, but not exhaustive, interest:

  • Lung diseases, including asthma, chronic obstructive pulmonary disease, cystic fibrosis, infectious diseases, interstitial lung diseases and lung tumors
  • Genetics
  • Lung development
  • Occupational and environmental factors
  • Pulmonary circulation
  • Pulmonary pharmacology and therapeutics
  • Respiratory critical care
  • Respiratory immunology
  • Respiratory physiology
  • Sleep
  • Circulation

Editorial standards and procedures:

Submissions, excluding editorials, letters to the editor and dedications, will be peer reviewed by two reviewers.  Reviewers are required to provide fair, balanced and constructive reports.  

Under our Fairness in Peer Review Policy authors may appeal against reviewers' recommendations which are ill-founded, unobjective or unfair.  Appeals are considered by the Editor in Chief or Associate Editor.

Papers are not sent to peer reviewers following submission of a revised manuscript. Editorial decisions on re-submitted papers are based on the author's response to the initial peer review report.

Indexing:

This journal is indexed by the following services:

  • Google Scholar
  • CAS
  • DOAJ
  • SCOPUS
  • Embase

SPARC Europe Seal award winner:

This journal has been awarded a SPARC Europe Seal. The Seal is an initiative of SPARC Europe (Scholarly Publishing and Academic Resources Coalition) and the Directory of Open Access Journals (DOAJ) which is awarded to journals applying a Creative Commons CC-BY copyright license and that make journal metadata accessible to DOAJ.  

Amongst other important services DOAJ makes metadata OAI-compliant.  This in turn enhances the visibility of papers and allows OAI-harvesters to include the details of journal articles in their services. We encourage readers to make use of this valuable resource.  The DOAJ search page is available here.

National Institutes of Health Public Access Policy compliant:

As of April 7 2008, the US NIH Public Access Policy requires that all peer reviewed articles resulting from research carried out with NIH funding be deposited in the Pubmed Central archive.

If you are an NIH employee or grantee Libertas Academica will ensure that you comply with the policy by depositing your paper at Pubmed Central on your behalf. 



Editor in Chief's call for papers
 
 
 


The Unpredictable Effect of Changing Cardiac Output on Hypoxemia after Acute Pulmonary Thromboembolism

Authors: John Y. C. Tsang, Wayne J. E. Lamm, Blazej Neradilek, Nayak L. Polissar and Michael P. Hlastala
Publication Date: 06 Jun 2008
Clinical Medicine: Circulatory, Respiratory and Pulmonary Medicine 2008:2 73-84

John Y. C. Tsang1, Wayne J. E. Lamm2, Blazej Neradilek3, Nayak L. Polissar3 and Michael P. Hlastala2

1James Hogg iCAPTURE Research Laboratory, Division of Critical Care Medicine, Department of Medicine, University of British Columbia, Vancouver, B.C., Canada. 2Departments of Physiology and Biophysics and of Medicine, University of Washington, Seattle, WA 98195.  3The Mountain-Whisper-Light Statistical Consulting, Seattle, WA 98112.

Abstract

Previous studies reported that the degree of hypoxemia following acute pulmonary thromboembolism (APTE) was highly variable and that its mechanism was mainly due to the creation of many high and low ventilation/perfusion (V/Q) units, as a result of the heterogeneous regional blood flow (Q) caused by embolic obstruction. We studied the effect of changing cardiac output (Qt) on gas exchange after APTE in 5 embolized piglets (23 ± 3 Kg), using Dobutamine intermittently at approximately 20 µg/kg/min for 120 minutes. The distribution of ventilation (V) and perfusion (Q) at various times was mapped using fluorescent microspheres in 941 ± 60 lung regions. After APTE, increase in Qt by Dobutamine improved venous oxygen tension (PvO2) but arterial PaO2 did not change consistently. On the other hand, cluster analysis showed that the V/Q ratio of most lung regions was lowered due to increases in Q at the same time. We concluded that the effect of changing cardiac output on gas exchange following APTE was affected by the simultaneous and varying balance between the changing V/Q mismatch and the concomitantly changing PvO2, which might explain the unpredictability of PaO2 in the clinical setting.



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