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Microbiology Insights

Synopsis: An open access, peer reviewed electronic journal that covers microbiology.


Indexing: 4 major databases. Pubmed indexing for NIH-funded research.

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About this journal

ISSN: 1178-6361


Aims and scope:

Microbiology Insights is a peer-reviewed, open access journal which encompasses all aspects of the study of microbiology. Studies on all aspects of both prokaryotic and eukaryotic microorganisms and viruses are welcome. Areas such as functionality, infectious disease, food-borne pathogens, drug resistance and antimicrobials, industrial applications and more are also incorporated in this journal. Microorganisms are of increasing importance today, in terms of subjects of study as a way of understanding more complex organisms and processes, as an industrial and medical tool, and also a threat. Open access online journals are more accessible and publish rapidly, allowing greater dissemination of knowledge in this crucial field.

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Submissions, excluding editorials, letters to the editor and dedications, will be peer reviewed by two reviewers.  Reviewers are required to provide fair, balanced and constructive reports.  

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As of April 7 2008, the US NIH Public Access Policy requires that all peer reviewed articles resulting from research carried out with NIH funding be deposited in the Pubmed Central archive.

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Preliminary Study and Improve the Production of Metabolites with Antifungal Activity by A Bacillus Sp Strain IBA 33

Authors: María Antonieta Gordillo, Antonio Roberto Navarro, Lidia María Benitez, Marta Inés Torres de Plaza and Maria Cristina Maldonado
Publication Date: 08 Apr 2009
Microbiology Insights 2009:2 15-24

María Antonieta Gordillo1, Antonio Roberto Navarro1, Lidia María Benitez2, Marta Inés Torres de Plaza2 and Maria Cristina Maldonado1

1Instituto de Biotecnología, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 465, San Miguel de Tucumán, (4000), Argentina. 2Cátedra de Matemática, Facultad de Ciencias Naturales e Instituto Miguel Lillo, Universidad Nacional de Tucumán, Miguel Lillo 201, San Miguel de Tucumán (4000), Argentina.

Abstract

Bacillus sp strain IBA 33 metabolites, isolated from decaying lemon fruits, were evaluated for the control of pathogenic and non-pathogenic fungi (Penicillium digitatum, Geotrichum candidum, Penicillium expansum, Aspergillus clavatus, Aspergillus flavus, Aspergillus niger, and Fusarium moniliforme). These metabolites were recovered from Landy medium (LM) without aminoacids. In order to optimize metabolites production the LM was modified by adding different concentrations and sources of amino acids and carbohydrates at different culture conditions.

Bacillus sp strain IBA 33 metabolites efficacy to control fungi were evaluated with in vitro and in vivo assays. A. flavus growth inhibition was 52% with the metabolites of Bacillus sp strain IBA 33 recovered from LM (MBLM) in vitro assays. MBLM supplemented with 0.5% glutamic acid, inhibited the growth of P. digitatum, G. candidum, A. clavatus, A. niger and F. moniliforme by 65%, 88.44%, 84%, 34% and 92% respectively. The highest inhibition of P. expansum was 45% with MBLM supplemented with 0.5% aspartic acid. Similar results were obtained in vivo assays. These results showed that Bacillus sp strain IBA 33 metabolites specificity against fungi depended on the composition of the LM.

Categories: Microbiology


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