Posted Wed, Sep, 25,2013
Published today in Virology: Research and Treatment is a new review by Katarzyna Kaczmarek, Ayana Morales and Andrew J. Henderson. Read more about this paper below:
Title
T Cell Transcription Factors and Their Impact on HIV Expression
Abstract
By targeting CD4+ effector T cells, HIV has a dramatic impact on the depletion, expansion and function of the different polarized T cell subsets. The maturation of T cell lineages is in part driven by intrinsic transcription factors that potentially influence how efficiently HIV replicates. In this review, we explore whether transcription factors that are required for polarizing T cells influence HIV replication. In particular, we examine provirus transcription as well as the establishment and maintenance of HIV latency. Furthermore, it is suggested these factors may provide novel cell-specific therapeutic strategies for targeting the HIV latent reservoir.
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Biomarker Insights Paper Endorsed by Editor in ChiefWed 07 Oct, 2015
Interview with Professor Jamie DaviesHaving just published in a Libertas Academica journal (Evolutionary Bioinformatics) for the first time, I can attest that I was impressed by the process. Every stage from submission to typesetting and correspondence on matters relating to publishing was simple and efficient. In addition to this, regular updates of the status of the manuscript (with clear explanation of the status) enabled the process to be transparent and informative. I would not hesitate to use Libertas Academica ...
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