Posted Wed, Feb, 20,2013
Published today in Gene Expression to Genetical Genomics is a new short report by Frida Mesel Casanova, Rubens Tomio Honda, Monica Stropa Ferreira-Nozawa, Paulo Henrique Rocha Aride and Sérgio Ricardo Nozawa. Read more about this paper below:
Title
Effects of Copper and Cadmium Exposure on mRNA Expression of Catalase, Glutamine Synthetase, Cytochrome P450 and Heat Shock Protein 70 in Tambaqui Fish (Colossoma Macropomum)
Abstract
In this work the authors evaluated the expression of cat, glu, cypP450, hsp70 and 18S RNA in Colossoma macropomum following exposure to copper and cadmium by semi-quantitative RT-PCR and quantitative qRT-PCR. In RT-PCR and qRT-PCR hsp70 expression was highest after exposure to copper for 3 hours (h). glu expression increased after exposure to cadmium, regardless of time. cat expression increased after the first hour of exposure to both metals, and decreased after 3 hs. cyp450 expression was higher when compared to controls in exposed fish regardless of metal and exposure time. cyp450 expression after exposure to copper for 3 h was twice that recorded after 1 h. In the presence of cadmium, cyp450 expression was higher in the animals exposed for 1 h and lower at 3 h. Therefore, toxicology tests and biomonitoring based on molecular markers should focus on a set of molecular and/or environmental parameters, rather than isolated markers.
Click here to learn more about the article, download it and comment
Posted in: Articles Published
News Categories
Thu 08 Oct, 2015
Published This Week (5th - 9th October)Thu 08 Oct, 2015
Biomarker Insights Paper Endorsed by Editor in ChiefWed 07 Oct, 2015
Interview with Professor Jamie DaviesMy experience in publishing my paper in this journal was great. The process was non-complicated and friendly. The editorial team was cooperative and responded promptly and efficiently to my queries. The peer reviewers were professional and fair. Their comments and recommendations added value to my paper. I consider publishing my future research in this journal and recommend it to my colleagues.
Facebook Google+ Twitter
Pinterest Tumblr YouTube