This research profile is on Clinical Medicine: Endocrinology and Diabetes author Dr Hiro Koshiyama. Clinical Medicine: Endocrinology and Diabetes is an open access journal published by Libertas Academica. Dr Hiro Koshiyama is the author of Diabetes Mellitus as Dysfunction of Interactions Among all Organs: “Ominous Orchestra of Organs”.

Editor in Chief Dr Victor Gault has recently issued a call for papers.

Primary research focus:

Clinical endocrinology and diabetes.

Notable developments:

We first demonstrated the IMT reduction after thiazolidinedione (TZD), which led to many papers about antiatherogenic actions of TZD.

Research collaborators:

Drs Nobuya Inagaki and Yutaka Seino:

• Koshiyama H, Taniguchi A, Tanaka K, Kagimoto S, Fujioka Y, Hirata K, Nakamura Y, Iwakura A, Hara K, Yamamoto T, Kuroe A, Ohya M, FujimotoS, Hamamoto Y, Honjo S, Ikeda H, Nabe K, Tsuda K, Inagaki N, Seino Y, Kume N. Effects of pitavastatin on lipid profiles and high-sensitivity CRP in Japanese subjects with hypercholesterolemia :Kansai Investigation of Statin for Hyperlipidemic Intervention in Metabolism and Endocrinology (KISHIMEN) Investigators. Journal of Atherosclerosis and Thrombosis 2008; 15(6): 345-35. [Pubmed]

Reasons for working in this area:

After I entered Prof Hiroo Imura's Lab in 1984.

View of open access publishing:

Open journal is very good for discussion.

Notable recent papers:

• Koshiyama H, Ogawa Y, Tanaka K, Tanaka I. Diabetes mellitus as dysfunction of interactions among all organs: “ominous orchestra of organs”. Clinical Medicine: Endocrinology and Diabetes 2008; 1:1-6. [Journal]

• Nabe K, Nomura K, Ikeda H, Honjo S, Wada Y, Kimura T, Aoyama T, Hamamoto Y, Koshiyama H. Depression is one component of metabolic syndrome. Medical Hypotheses Research 2008;4(2):79-83. [Journal]

• Ikeda H, Nakamura Y, Minamikawa J, Honjo S, Hamamoto Y, Wada Y, Nabe K, Koshiyama H. Comparison of Effects of Amlodipine and Angiotensin Receptor Blockers on the Intima-media Thickness of Carotid Arterial Wall (AAA Study: Amlodipine vs ARB in Atherosclerosis Study) Diabetes Res Clin Pract 2009; 83:117-118.

• Ikeda H, Honjo S, Hamamoto Y, Wada Y, Nabe K, Koshiyama H. Olmesartan reduced microalbuminuria in Japanese subjects with type 2 diabetes. (letter). Diabetes Res Clin Pract 2009; 83: 50-53. [Pubmed]

• Kimura T, Ikeda H, Fujikawa J, Nomura K, Aoyama T, Nabe K, Hamamoto Y, Honjo S, Koshiyama H. Usefulness of serum cystatin C as a marker of diabetic nephropathy in Japanese subjects with type 2 diabetes. Diabetes Res Clin Pract 2009 83(2):e58-61. [Journal]

• Handbook of Endocrinology & Metabolism, 3rd ed. [Amazon (Japanese)]

Further information about Dr Koshiyama:

• Center for Endocrinology and Diabetes

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