Publication Date: 07 Oct 2013
Type: Case report
Journal: Clinical Medicine Insights: Oncology
Citation: Clinical Medicine Insights: Oncology 2013:7 257-262
Primary synovial sarcoma (SS) of the kidney is a rare neoplasm and its presenting features are similar to other common renal tumors, making early diagnosis difficult. To date, few cases have been reported in the literature. Primary renal SSs can exist in either a monophasic or a biphasic pattern, the former being more common and tending to have a better prognosis than the biphasic variant. Herein we describe a case of primary renal SS that was diagnosed based on histopathology and immunohistochemistry after radical nephrectomy. Fusion gene product analysis was also done by FISH and RT-PCR. Patient follow-up and literature review are presented, focused on systemic therapy. We highlight that these tumors should be correctly diagnosed as clinical results and specific treatment are distinct from primary epithelial renal cell carcinoma. Adjuvant chemotherapy should be tailored for each patient in the management of disease, although its role still remains unclear.
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The team at Libertas Academica stands above the pack as publishers of academic journals. My recent article in Clinical Medicine Insights: Oncology was handled very professionally throughout the process. They have my highest regards.
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