Once-Daily MMX Mesalamine in the Management of Ulcerative Colitis

Wojciech Blonski; Anna M. Buchner; Gary R. Lichtenstein

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Clinical Medicine Insights: Gastroenterology

Once-Daily MMX Mesalamine in the Management of Ulcerative Colitis

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Wojciech Blonski, Anna M. Buchner and Gary R. Lichtenstein

Clinical Medicine Insights: Gastroenterology 2011:4 7-13

Review

Published on 25 May 2011

DOI: 10.4137/CGast.S4276

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Abstract

Mesalamine (5-ASA) has been the mainstay therapy of mild to moderate active ulcerative colitis both as an induction and maintenance treatment. Multimatrix system (MMX) 5-ASA is a recently developed formulation of 5-ASA allowing for slow and gradual release of 5-ASA throughout the entire colon. This review article discusses the structure, pharmacokinetics, efficacy and safety of this new 5-ASA formulation.

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