Dr Otsuki is the author of Immunological changes in mesothelioma patients and their experimental detection which was recently published in Clinical Medicine: Circulatory, Respiratory and Pulmonary Medicine.

The Editor in Chief of Clinical Medicine: Circulatory, Respiratory and Pulmonary Medicine recently issued a call for papers.

Dr Otsuki is a member of our favorite author program. Under the program authors are eligible to receive: prioritised peer review, prioritised author PDF, and an article processing fee discount. All former authors are eligible to join the favorite author program.

What is the primary focus of your research?

Immunological effects of silica/asbestos.

What are the most exciting developments arising from current research in your area?

The discovery of regulatory T cell anf Th17 cell.

Who are your main collaborators? Please describe your work with them

Dr. Takashi Kishimoto; Prof. Takashi Nakano.

How did you come to be working in your research area?

 

My former boss was working on it.

What articles and/or books have you published recently?

• Nishimura Y, Miura Y, Maeda M, KUmagai N, Murakami S, Hayashi H, Fukuoka K, Nakano T, Otsuki T. Impairment in cytotoxicity and expression of NK-cell activating receptors on human NK cells following exposure to asbestos fibers. Int J Immunopathol Pharmacol 2009 Jul-Sep;22(3):579-90

• Nishimura Y, Maeda M, Kumagai N, Hayashi H, Miura Y, Otsuki T. Decrease in phosphorylation of ERK following decreased expression of NK-cell activating receptors in human NK cell line exposed to asbestos. Int J Immunopathol Pharmacol (in press)

• Hayashi H, Maeda M, Murakami S, Kumagai N, Chen Y, Hatayama T, Katoh M, Miyahara N, Yamamoto S, Yoshida Y, Nishimura Y, Kusaka M, Fujimoto W, Otsuki T. Soluble interleukin-2 receptor as an indicator of immunological disturbance found in silicosis patients Int J Imminopathol Pharmacol 2009 Jan-Mar;22(1):53-62

• Takahashi K, Otsuki T, Mase M, Kawado T, Kotani M, Nishimura Y, Maeda M, Murakami S, Kumagai N, Hayashi H, Chen Y, Shirahama T, Miura Y, Morimoto K. Two weeks of abidance in negatively-charged air conditions causes alteration of natural killer cell function. Int J Immunopathol Pharmacol 22(2); 333-342, 2009

• Murakami S-i, Otsuki T, Maeda M, Miura Y, Morii S, Kiyokane K, Hayakawa S-i, Maeda A, Imakawa T, Harada S, Handa T, Nishimura Y, Murakami S, Kumagai N, Hayashi H, Chen Y, Suemori S-i, Fukushima Y, Nishida S,Fukushima K. Effects of Vitamin D receptor (VDR) gene polymorphism on low-resistance training using exercise machines (“Power rehabilitation”) as rehabilitation program. Int J Mol Med. 2009 Jan;23(1):81-8

• Otsuki T. Biological effects of fibrous and particulated substances and related areas: foreword. (Special Features: Biological effects of fibrous and particulated substances and related areas). Environ Health Prev Med214-215; 2009

• Murakami S, Nishimura Y, Maeda M, Kumagai N, Hayashi H, Chen Y, Kusaka K, Kishimoto T, Otsuki t. Cytokine alteration and speculated immunological pathophysiology in silicosis and asbestos-related diseases. Environ Health Prev Med 14(4): 216-222, 2009

More information

• Kawasaki Medical School, Dept of Hygiene

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