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Lung Function, Insulin and Metabolic Syndrome

Posted Tue, Mar, 25,2014

Published today in Japanese Clinical Medicine is a new original research article by Yayoi Yamamoto, Junko Oya, Tomoko Nakagami and Yasuko Uchigata.  Read more about this paper below:

Title

Association Between Lung Function and Metabolic Syndrome Independent of Insulin in Japanese Men and Women

Abstract

Purpose: We examined the cross-sectional association between lung function and metabolic syndrome (MetS), independent of fasting immunoreactive insulin (F-IRI).

Methods: A total of 3,072 middle-aged, apparently healthy subjects who participated in a general health check-up were included. Lung function, which was expressed as forced vital capacity (%FVC predicted) or forced expiratory volume in 1 second (FEV1% predicted) was examined. Multivariable logistic regression analysis was performed to assess the association between lung function and MetS.

Results: Men with the lowest quartile of FVC% predicted, or those with the lowest quartile of FEV1% predicted, had a 3.5-fold or 2.6-fold increased risk of MetS, respectively, compared with those with the highest quartile of FVC% predicted or FEV1% predicted. F-IRI had a positive, significant, and independent association with MetS in both sexes.

Conclusion: Impaired lung function increased the risk of MetS, independent of F-IRI and smoking in men, but not in women.

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