Posted Tue, Nov, 19,2013
Published today in Clinical Medicine Insights: Blood Disorders is a new case report by Karlos Z. Oregel, Jeremy Ramdial and Stefan Glück. Read more about this paper below:
Title
Nonsteroidal Anti-inflammatory Drug Induced Thrombotic Thrombocytopenic Purpura
Abstract
A 21-year-old male presented to the emergency department after a 5-day history of recurrent vomiting and decreased urine output. History revealed ingestion of ibuprofen. During the diagnostic workup, the following was identified: white blood cell count 13.4 (×10(3)/mcL), hemoglobin 11.9 (×10(6)/mcL) with an MCV of 73 fL, hematocrit 34% and platelets were 31,000/mcL, sodium of 130 mmol/L, potassium of 5.1 mmol/L, chloride of 83 mmol/L, bicarbonate of 21 mmol/L, blood urea nitrogen of 184 mg/dL and creatinine of 19.1 mg/dL. He was later diagnosed with thrombotic thrombocytopenic purpura (TTP) based on the fact that he presented with most components of the TTP pentad (except for fever), which included altered mental status, acute kidney injury, thrombocytopenia, and evidence of red cell fragmentation and his ADAMTS13 level was found to be less than 10% prior to therapy. The patient then received plasma exchange, oral corticosteroids, and hemodialysis, which led to a full recovery of platelet count and renal function.
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Biomarker Insights Paper Endorsed by Editor in ChiefWed 07 Oct, 2015
Interview with Professor Jamie DaviesI had a great experience publishing my case report in this journal. The submission to editorial decision time was very short, and in addition there were frequent updates by email regarding the status of the manuscript. I thought the editors were very friendly and supportive. I would recommend this journal to anyone wishing to publish his/her research in a quality journal with a decent article processing speed. I also appreciate the support given by the ...
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