Posted Mon, Sep, 16,2013
Published today in International Journal of Tryptophan Research is a new review article by Simon P. Jones, Gilles J. Guillemin and Bruce J. Brew. Read more about this paper below:
Title
The Kynurenine Pathway in Stem Cell Biology
Abstract
The kynurenine pathway (KP) is the main catabolic pathway of the essential amino acid tryptophan. The KP has been identified to play a critical role in regulating immune responses in a variety of experimental settings. It is also known to be involved in several neuroinflammatory diseases including Huntington’s disease, amyotrophic lateral sclerosis, and Alzheimer’s disease. This review considers the current understanding of the role of the KP in stem cell biology. Both of these fundamental areas of cell biology have independently been the focus of a burgeoning research interest in recent years. A systematic review of how the two interact has not yet been conducted. Several inflammatory and infectious diseases in which the KP has been implicated include those for which stem cell therapies are being actively explored at a clinical level. Therefore, it is highly relevant to consider the evidence showing that the KP influences stem cell biology and impacts the functional behavior of progenitor cells.
Click here to learn more about the article, download it and comment
Posted in: Articles Published
News Categories
Thu 08 Oct, 2015
Published This Week (5th - 9th October)Thu 08 Oct, 2015
Biomarker Insights Paper Endorsed by Editor in ChiefWed 07 Oct, 2015
Interview with Professor Jamie DaviesOur experience publishing in Clinical Medicine Insights: Oncology was the easiest and most user-friendly interface we have encountered. The staff were very attentive to us and kept us posted at every step of the process. It was rewarding to have our article appear in press within weeks, compared to months at other journals.
Facebook Google+ Twitter
Pinterest Tumblr YouTube