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Live Birth from Previously Vitrified Oocytes, After Trophectoderm Biopsy

Posted Wed, Sep, 11,2013

Published today in Clinical Medicine Insights: Reproductive Health is a new case report by Jamie A. Grifo, Brooke Hodes-Wertz, Hsiao Ling Lee, Esmeralda Ampeloquio, Melicia Clarke-Williams, Alexis Adler, Santiago Munné and Alan S. Berkeley.  Read more about this paper below:

Title

Live Birth from Previously Vitrified Oocytes, After Trophectoderm Biopsy, Revitrification, and Transfer of a Euploid Blastocyst

Abstract

Our objective is to describe a successful live birth from oocyte vitrification followed by thaw, fertilization, blastocyst culture, trophectoderm biopsy, vitrification, and subsequent thaw. Fifteen mature oocytes were frozen from a patient with uterine factor infertility. Thirteen oocytes survived the thaw, and five underwent trophectoderm biopsy and were refrozen. Three euploid embryos were obtained. A single euploid embryo was transferred in the second thaw cycle to a known recipient leading to the delivery of a normal male infant. This case report is proof of the concept that preimplantation screening and diagnosis is an option for fertility preservation patients.

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