Posted Thu, Sep, 05,2013
Published today in Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders is a new case report article by Ross A. Hauser, MD and Amos Orlofsky. Read more about this paper below:
Title
Regenerative Injection Therapy with Whole Bone Marrow Aspirate for Degenerative Joint Disease: A Case Series
Abstract
Regenerative therapeutic strategies for joint diseases usually employ either enriched concentrates of bone marrow-derived stem cells, chondrogenic preparations such as platelet-rich plasma, or irritant solutions such as hyperosmotic dextrose. In this case series, we describe our experience with a simple, cost-effective regenerative treatment using direct injection of unfractionated whole bone marrow (WBM) into osteoarthritic joints in combination with hyperosmotic dextrose. Seven patients with hip, knee or ankle osteoarthritis (OA) received two to seven treatments over a period of two to twelve months. Patient-reported assessments were collected in interviews and by questionnaire. All patients reported improvements with respect to pain, as well as gains in functionality and quality of life. Three patients, including two whose progress under other therapy had plateaued or reversed, achieved complete or near-complete symptomatic relief, and two additional patients achieved resumption of vigorous exercise. These preliminary findings suggest that OA treatment with WBM injection merits further investigation.
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Interview with Professor Jamie DaviesThis is the second time I have submitted a paper to Palliative Care: Research and Treatment for possible publication. In both instances, my experience with Libertas Academica was very good from submission to acceptance. The peer reviewers' comments were insightful, very constructive, and extremely helpful. The author interface was user-friendly. The publishing process was fast and convenient. I highly recommend this journal.
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