Posted Tue, Aug, 13,2013
Published today in Clinical Medicine Insights: Oncology is a new review article by Fuad El Rassi and Martha Arellano. Read more about this paper below:
Title
Update on Optimal Management of Acute Myeloid Leukemia
Abstract
Acute myeloid leukemia (AML) represents a malignant accumulation of immature myeloid cells in the marrow, presenting with impaired hematopoiesis and its attendant complications, including bleeding, infection, and organ infiltration. Chromosomal abnormalities remain the most powerful predictors of AML prognosis and help to identify a subgroup with favorable prognosis. However, the majority of AML patients who are not in the favorable category succumb to the disease. Therefore, better efforts to identify those patients who may benefit from more aggressive and investigational therapeutic approaches are needed. Newer molecular markers aim at better characterizing the large group of intermediate-risk patients and to identify newer targets for therapy. A group that has seen little improvement over the years is the older AML group, usually defined as age ≥60. Efforts to develop less intensive but equally efficacious therapy for this vulnerable population are underway.
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Thu 08 Oct, 2015
Published This Week (5th - 9th October)Thu 08 Oct, 2015
Biomarker Insights Paper Endorsed by Editor in ChiefWed 07 Oct, 2015
Interview with Professor Jamie DaviesI have had the honor to work with the professional team at Bioinformatics and Biology Insights. The reviewers' recommendations were very interesting and I am satisfied of the article quality. I encourage scientists to submit their work to Libertas Academica.
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