Posted Mon, Jul, 29,2013
Published today in Genetics & Epigenetics is a new review article by Cong-jun Li. Read more about this paper below:
Title
DNA Demethylation Pathways: Recent Insights
Abstract
DNA methylation is a major epigenetic regulatory mechanism for gene expression and cell differentiation. Until recently, it was still unclear how unmethylated regions in mammalian genomes are protected from de novo methylation and whether or not active demethylating activity is involved. Even the role of molecules and the mechanisms underlying the processes of active demethylation itself is blurred. Emerging sequencing technologies have led to recent insights into the dynamic distribution of DNA methylation during development and the role of this epigenetic mark within a distinct genome context, such as the promoters, exons, or imprinted control regions. This review summarizes recent insights on the dynamic nature of DNA methylation and demethylation, as well as the mechanisms regulating active DNA demethylation in mammalian cells, which have been fundamental research interests in the field of epigenomics.
Click here to learn more about the article, download it and comment
Posted in: Articles Published
News Categories
Thu 08 Oct, 2015
Published This Week (5th - 9th October)Thu 08 Oct, 2015
Biomarker Insights Paper Endorsed by Editor in ChiefWed 07 Oct, 2015
Interview with Professor Jamie DaviesI thank Libertas for the guidance, speed and encouragement they provided from my first submission until publication. I appreciate the patience and support of everyone I communicated with. Your services are user-friendly. I intend to submit more articles to your journals.
Facebook Google+ Twitter
Pinterest Tumblr YouTube