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Unique Relationship of Anti-GluR Antibody-Positive Encephalitis

Posted Mon, Jun, 24,2013

Published today in Clinical Medicine Insights: Case Reports is a new case report article by Kosuke Matsuzono, Tomoko Kurata, Shoko Deguchi, Toru Yamashita, Kentaro Deguchi, Yoshio Ikeda and Koji Abe.  Read more about this paper below:

Title

Two Unique Cases with Anti-GluR Antibody-Positive Encephalitis

Abstract

We report two cases of anti-glutamic acid receptor (anti-GluR) antibody-positive encephalitis in males with symptoms such as Parkinsonism, urinary retention, and paralytic ileus. Although non-herpetic encephalitis typically shows magnetic resonance imaging (MRI) lesions in the limbic system during early stages, the present cases showed MRI lesions during later stages in the bilateral claustrum and pons. In both cases, anti-GluRε2 and δ2 antibodies were later shown to be positive in the cerebrospinal fluid but negative in the serum. Although early detection of anti-GluR antibodies is essential, early treatment may be significantly more important.

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