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Evolving Pharmacotherapies for Metastatic Melanoma

Posted Fri, Jun, 21,2013

Published today in Clinical Medicine Insights: Oncology is a new review by April K.S. Salama.  Read more about this paper below:

Title

Evolving Pharmacotherapies for the Treatment of Metastatic Melanoma

Abstract

Metastatic melanoma remains a difficult disease to treat, and long term survivors are rare. Over the past few years, however, breakthroughs in both immunotherapy as well as targeted agents have had a tremendous impact on patients diagnosed with this disease. This review summarizes recent advances in systemic therapies for melanoma, including immune modulators directed against cytotoxic T lymphocyte associated antigen-4 (CTLA-4) and programmed death-1 (PD-1), as well as a number of targeted agents. These approaches hold great promise as the landscape of therapeutic options for advanced melanoma continues to evolve.

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