Posted Mon, May, 27,2013
Published today in Bioinformatics and Biology Insights is a new original research article by Markus A. Grohme, Brahim Mali, Weronika Welnicz, Stephanie Michel, Ralph O. Schill and Marcus Frohme. Read more about this paper below:
Title
The Aquaporin Channel Repertoire of the Tardigrade Milnesium tardigradum
Abstract
Limno-terrestrial tardigrades are small invertebrates that are subjected to periodic drought of their micro-environment. They have evolved to cope with these unfavorable conditions by anhydrobiosis, an ametabolic state of low cellular water. During drying and rehydration, tardigrades go through drastic changes in cellular water content. By our transcriptome sequencing effort of the limno-terrestrial tardigrade Milnesium tardigradum and by a combination of cloning and targeted sequence assembly, we identified transcripts encoding eleven putative aquaporins. Analysis of these sequences proposed 2 classical aquaporins, 8 aquaglyceroporins and a single potentially intracellular unorthodox aquaporin. Using quantitative real-time PCR we analyzed aquaporin transcript expression in the anhydrobiotic context. We have identified additional unorthodox aquaporins in various insect genomes and have identified a novel common conserved structural feature in these proteins. Analysis of the genomic organization of insect aquaporin genes revealed several conserved gene clusters.
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Interview with Professor Jamie DaviesAs an open access journal with an international audience, Air, Soil and Water Research has a tremendous worldwide impact. Peer reviewing process is essential to maintain the high standard of quality of published papers, and I have thoroughly enjoyed my participation as a reviewer for Air, Soil and Water Research. The online review system is very easy and simply to use. I am looking forward to peer reviewing additional articles in the future. ...
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