Posted Thu, Mar, 07,2013
Published today in Infectious Diseases: Research and Treatment is a new original research article by Ballah Akawu Denue, Mohammed Bashir Alkali, Ali Usman Abjah, Ibrahim Musa Kida, Babajide Ajayi and Bala Zira Fate. Read more about this paper below:
Title
Changes in Lipid Profiles and Other Biochemical Parameters in HIV-1 Infected Patients Newly Commenced on HAART Regimen
Abstract
Abnormalities of lipid metabolism are common in human immunodeficiency virus (HIV)-infected patients and tend to be accentuated in those receiving antiretroviral therapy, particularly with protease inhibitors (PIs). However, there is a dearth of information on serum lipid profiles and biochemical parameters among treatment-naive HIV-positive patients in our environment. We found that after 24 months of highly active antiretroviral therapy (HAART), there was a significant increase in serum lipids. After 24 months of HAART, renal impairment was associated with a low increase in mean HDL and a high increase in triglycerides (TG). In conclusion, abnormality of serum lipid is common and showed female preponderance among treatment-naive HIV patients in our environment. Patients with HIV infection on HAART should be screened for lipid disorders given their high prevalence as observed in this study, because of its potential for morbidity and mortality in patients on HAART.
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Thu 08 Oct, 2015
Published This Week (5th - 9th October)Thu 08 Oct, 2015
Biomarker Insights Paper Endorsed by Editor in ChiefWed 07 Oct, 2015
Interview with Professor Jamie DaviesDrug Target Insight offers a rapid scientific evaluation of submitted manuscripts. The editorial staff is extremely helpful in the guidance through the process. By recruitment of several references, the review process has the chance to be more fair and objective compared with when only a single referee is used. I can strongly recommend to publish research articles in the journal.
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