Close
Help




JOURNAL

Clinical Medicine Insights: Gastroenterology

Is ESR Important for Predicting Post-ERCP Pancreatitis?

Submit a Paper


Clinical Medicine Insights: Gastroenterology 2015:8 23-27

Original Research

Published on 05 May 2015

DOI: 10.4137/CGast.S18938


Further metadata provided in PDF



Sign up for email alerts to receive notifications of new articles published in Clinical Medicine Insights: Gastroenterology

Abstract

Background: Pancreatitis remains the most common complication of endoscopic retrograde cholangiopancreatography (ERCP), resulting in substantial morbidity and occasional mortality. There are notable controversies and conflicting reports about risk factors of post-ERCP pancreatitis (PEP).

Aim: To evaluate the potential risk factors for PEP at a referral tertiary center, as a sample of the Iranian population.

Materials and methods: Baseline characteristics and clinical as well as paraclinical information of 780 patients undergoing diagnostic and therapeutic ERCP at Taleghani hospital in Tehran between 2008 and 2012 were reviewed. Data were collected prior to the ERCP, at the time of the procedure, and 24–72 hours after discharge. PEP was diagnosed according to consensus criteria.

Results: Of the 780 patients who underwent diagnostic ERCP, pancreatitis developed in 26 patients (3.3%). In the multivariable risk model, significant risk factors with adjusted odds ratios (ORs) were age <65 years (OR = 10.647, P = 0.023) and erythrocyte sedimentation rate (ESR) >30 (OR = 6.414, P < 0.001). Female gender, history of recurrent pancreatitis, pre-ERCP hyperamylasemia, and difficult or failed cannulation could not predict PEP. There was no significant difference in the rate of PEP in wire-guided cannulation versus biliary cannulation using a sphincterotome and contrast injection as the conventional method.

Conclusions: Performing ERCP may be safer in the elderly. Patients with high ESR may be at greater risk of PEP, which warrants close observation of these patients for signs of pancreatitis after ERCP.



Downloads

PDF  (751.57 KB PDF FORMAT)

RIS citation   (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)

BibTex citation   (BIBDESK, LATEX)

XML

PMC HTML


Sharing


What Your Colleagues Say About Clinical Medicine Insights: Gastroenterology
I had a really positive experience publishing in Clinical Medicine Insights: Gastroenterology.  The submission process is easy and friendly.  The review process is very accurate with a considerable quantity of reviewers who give helpful and reasonable suggestions.  The staff are professional and gives prompt email responses.  I recommend colleagues to consider publishing with Libertas Academica.
Dr Vincenzo Neri (University of Foggia, Foggia, Italy)
More Testimonials

Quick Links


New article and journal news notification services
Email Alerts RSS Feeds
Facebook Google+ Twitter
Pinterest Tumblr YouTube