Evolution of Cellular Inclusions in Bietti’s Crystalline Dystrophy

Emiko Furusato; J. Douglas Cameron; Chi-Chao Chan

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Ophthalmology and Eye Diseases

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Evolution of Cellular Inclusions in Bietti’s Crystalline Dystrophy

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Authors: Emiko Furusato, J. Douglas Cameron and Chi-Chao Chan

Publication Date: 09 Mar 2010

Type: Review

Journal: Ophthalmology and Eye Diseases

Citation: Ophthalmology and Eye Diseases 2010:2 9-15

doi: 10.4137/OED.S2821

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Abstract

Bietti’s crystalline dystrophy (BCD) consists of small, yellow-white, glistening intraretinal crystals in the posterior pole, tapetoretinal degeneration with atrophy of the retinal pigment epithelium (RPE) and “sclerosis” of the choroid; in addition, sparking yellow crystals in the superficial marginal cornea are also found in many patients. BCD is inherited as an autosomal-recessive trait (4q35-tel) and usually has its onset in the third decade of life. This review focuses on the ultrastructure of cellular crystals and lipid inclusions of BCD.

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