A Case of Fahr’s Disease Presenting as Chorea Successfully Treated by the Use of Quetiapine
Syoichiro Kono1, Yasuhiro Manabe1, Tomotaka Tanaka1, Daiki Fujii1, Yasuko Sakai1, Hisashi Narai1, Nobuhiko Omori1 and Koji Abe2
1Department of Neurology, National Hospital organization okayama Medical Center, okayama, Japan. 2Department of Neurology, Graduate school of Medicine, Dentistry and pharmaceutical sciences, okayama University, okayama, Japan.
Abstract
We report a case of 30-year-old man presenting chorea in his legs. A brain computed tomography (CT) scan showed bilateral symmetric calcifications in the basal ganglia, thalamus, cerebellum and subcortical white matter. Laboratory studies showed no abnormalities of serum calcium, phosphate, PTH, lactic acid, pyruvic acid and cerebrospinal fluid. Under the diagnosis of Fahr’s disease (FD), we treated with quetiapine (75 mg/day), which completely abolished his symptoms and he showed no other side effect. Our experience suggests that quetiapine is well tolerated in FD patients and effectively treats chorea without extrapyramidal movement.
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