Close
Help




JOURNAL

Clinical Medicine Reviews in Vascular Health

Valsartan and Amlodipine: Safety and Efficacy in Stroke Prevention

Submit a Paper


Clinical Medicine Reviews in Vascular Health 2010:2

Review

Published on 15 Jul 2010

DOI: 10.4137/CMRVH.S5204


Further metadata provided in PDF



Sign up for email alerts to receive notifications of new articles published in Clinical Medicine Reviews in Vascular Health

Abstract

Stroke is one of the leading causes of death and disability worldwide. Controlling hypertension is known to be the most important treatment in preventing stroke. Reduction of blood pressure (BP) even below the normal range continues to reduce stroke risk. However, there are also thought to be blood pressure-independent effects of antihypertensive treatments, which differ between antihypertensive classes. Calcium channel blocker, amlodipine, and angiotensin receptor blocker, valsartan, represent the two antihypertensive drugs with supportive evidence for the prevention of stroke. Amlodipne and valsartan have favorable effects on stroke outcome as monotherapy, particularly in patients with high cardiovascular risk. There has been no study in which evaluated the effectiveness of the combination of these two agents, however, the combination of amlodipine and valsartan is well tolerated and the large BP reductions with this combination therapy would suggest that this might be an effective approach for stroke prevention.



Downloads

RIS citation   (ENDNOTE, REFERENCE MANAGER, PROCITE, REFWORKS)

BibTex citation   (BIBDESK, LATEX)


Sharing


What Your Colleagues Say About Clinical Medicine Reviews in Vascular Health
Publishing in Clinical Medicine Reviews in Vascular Health was a pleasant experience. The process was fast and fair. The staff were very professional and we were well informed of the progress of the manuscript.
Dr Abd A Tahrani MD (Birmingham Heartlands Hospital, University of Birmingham, UK)
More Testimonials

Quick Links


New article and journal news notification services
Email Alerts RSS Feeds
Facebook Google+ Twitter
Pinterest Tumblr YouTube