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Clinical Medicine Reviews in Vascular Health

The Prevention of Atherothrombotic Events in Adults with Acute Coronary Syndromes

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Clinical Medicine Reviews in Vascular Health 2011:3 117-139

Review

Published on 01 Nov 2011

DOI: 10.4137/CMRVH.S6639


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Abstract

The term acute coronary syndrome is used to describe a range of conditions that share a common underlying pathology of interrupted blood flow and subsequent damage to the myocardium. Acute coronary events are unpredictable and can rapidly become life-threatening, largely as a result of clot formation, and one of the primary treatment aims is to limit thrombosis. Such events are a major cause of hospitalization and death worldwide and thus the impact of advances in thrombocardiology is enormous. Acute coronary syndromes can be difficult to diagnose, and a successful clinical outcome depends on accurate assessment of individual risk which is then used to determine the treatment strategy. Recent advances fall in to two main areas: firstly the improvement in understanding of the clinical markers that allow more accurate risk stratification and, secondly, the development of new anti-thrombotic drugs. This review considers current approaches for the management of acute coronary syndromes, highlighting recent advances.



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Publishing in Clinical Medicine Reviews in Vascular Health was a pleasant experience. The process was fast and fair. The staff were very professional and we were well informed of the progress of the manuscript.
Dr Abd A Tahrani MD (Birmingham Heartlands Hospital, University of Birmingham, UK)
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