Targeting DNA Damage and Repair by Curcumin
Authors: Zhenyu Ji
Publication Date: 16 Feb 2010
Breast Cancer: Basic and Clinical Research 2010:4 1-3
Zhenyu Ji
Wellman Center for Photomedicine and the Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, 02114, USA.
Abstract
Curcumin is a compound with anti-tumor effects in a tolerable dose. A recent paper by Rowe et al described that curcumin induced DNA damage in triple negative breast cancer cells and regulated BRCA1 protein expression and modification. Related research and potential use of curcumin will be discussed in this article.
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