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Sigma Factors for Cyanobacterial Transcription

Authors: Sousuke Imamura and Munehiko Asayama
Publication Date: 22 Apr 2009
Gene Regulation and Systems Biology 2009:3 65-87

Sousuke Imamura and Munehiko Asayama

Laboratory of Molecular Genetics, School of Agriculture, Ibaraki University, 3-21-1 Ami, Inashiki, Ibaraki 300-0393, Japan.

Abstract

Cyanobacteria are photosynthesizing microorganisms that can be used as a model for analyzing gene expression. The expression of genes involves transcription and translation. Transcription is performed by the RNA polymerase (RNAP) holoenzyme, comprising a core enzyme and a sigma (σ) factor which confers promoter selectivity. The unique structure, expression, and function of cyanobacterial σ factors (and RNAP core subunits) are summarized here based on studies, reported previously. The types of promoter recognized by the σ factors are also discussed with regard to transcriptional regulation.

Categories: Gene expression